Effective inhibition in animals of viral pathogenesis by a ribozyme derived from RNase P catalytic RNA

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 31, 2008, Pages 10919-10924

  Bai, Yong ^a   Trang, Phong ^a   Li, Hongjian ^a   Kim, Kihoon ^a   Zhou, Tianhong ^a   Liu, Fenyong ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antisense; Cytomegalovirus; Gene targeting; Herpesvirus

Indexed keywords

CAPSID PROTEIN; MESSENGER RNA; PLASMID DNA; PROTEIN M1GS; RIBONUCLEASE P; RIBOZYME;

ANIMAL MODEL; ARTICLE; CATALYSIS; CELL GROWTH; CONTROLLED STUDY; CYTOMEGALOVIRUS; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVITY; GENE CONSTRUCT; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; HYDRODYNAMICS BASED TRANSFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; RIBOZYME THERAPY; RNA SEQUENCE; SURVIVAL; VIROGENESIS; VIRUS INFECTION; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS VIRULENCE;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CAPSID PROTEINS; DNA PRIMERS; GENE EXPRESSION REGULATION, VIRAL; GENE TARGETING; MICE; MICE, SCID; MUROMEGALOVIRUS; NIH 3T3 CELLS; RIBONUCLEASE P; RNA, CATALYTIC; VIRUS REPLICATION;

ANIMALIA; CYTOMEGALOVIRUS; HERPESVIRIDAE; MAIZE CHLOROTIC MOTTLE VIRUS; MIRIDAE; MURID HERPESVIRUS 1; MUS;

EID: 49449092136     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0804922105     Document Type: Article

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