Identification of drug meglumine interaction products using LC/MS and forced degradation studies

Journal of Liquid Chromatography and Related Technologies

Volumn 31, Issue 15, 2008, Pages 2331-2336

  Qiu, Fenghe ^a   Cobice, Diego ^b   Pennino, Scott ^a   Becher, Mariela ^b   Norwood, Daniel L ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^b Boehringer Ingelheim   (Argentina)

Author keywords

Drug excipient interaction; Forced degradation; LC MS; Meglumine

Indexed keywords

CHEMOTHERAPY; DEGRADATION; DRUG DELIVERY; DRUG DOSAGE; DRUG INTERACTIONS; DRUG PRODUCTS PLANTS; FLOW INTERACTIONS; SULFATE MINERALS; VIRUSES;

ACTIVE PHARMACEUTICAL INGREDIENT; CHE MICAL INTERACTIONS; DEGRADATION PRODUCTS; DRUG FORMULATIONS; DRUG-EXCIPIENT INTERACTION; FORCED DEGRADATION; HEPATITIS C VIRUS; LC/MS; MEGLUMINE; STABILITY STUDIES;

DRUG PRODUCTS;

ANTIVIRUS AGENT; EXCIPIENT; MEGLUMINE;

ARTICLE; CHEMICAL INTERACTION; DRUG DEGRADATION; DRUG FORMULATION; DRUG STABILITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

HEPATITIS C VIRUS;

EID: 49449090674     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070802281802     Document Type: Article

References (5)

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4. Rowe, R.C.; Sheskey, P.J.; Owen S.C., (Ed.), Meglumine, in Handbook of Pharmaceutical Excipients, 5th Ed.; Pharmaceutical Press, 2006; 457 pp.
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