Rapid analytical method development using multiparallel microfluidic high-performance liquid chromatography in support of pharmaceutical process research

Journal of Liquid Chromatography and Related Technologies

Volumn 31, Issue 15, 2008, Pages 2296-2304

  Sajonz, Peter ^a   Schafer, Wes ^a   Leonard, William R ^a   Gong, Xiaoyi ^a   Shultz, Scott ^a   Rosner, Thorsten ^a   Sun, Yongkui ^a   Welch, Christopher J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Asymmetric hydrogenation; Catalyst screening; Chromatography; High throughput; HPLC; Microfluidic; Multiparallel; Normal phase

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; DRUG PRODUCTS; ELECTRON BEAM LITHOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HYDROGENATION; LIQUID CHROMATOGRAPHY; NANOFLUIDICS;

ANALYTICAL METHODS; ASYMMETRIC HYDROGENATION; CATALYST SCREENING; CATALYTIC HYDROGENATIONS; CHROMATOGRAPHY; ENANTIOSELECTIVE; HIGH THROUGHPUT; HIGH THROUGHPUT SCREENING; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH-THROUGHPUT EXPERIMENTATION; HPLC; METHOD DEVELOPMENT; MICROFLUIDIC; MULTIPARALLEL; NORMAL PHASE; PHARMACEUTICAL INTERMEDIATES; PROCESS DEVELOPMENTS; REAL-WORLD;

THROUGHPUT;

ANALYTIC METHOD; ARTICLE; CATALYSIS; ENANTIOSELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; HYDROGENATION; MICROFLUIDIC ANALYSIS;

EID: 49449088961     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070802281653     Document Type: Article

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