Cytotoxic effect of root extract of Tiliacora racemosa and oil of Semecarpus anacardium nut in human tumour cells

Phytotherapy Research

Volumn 18, Issue 8, 2004, Pages 595-600

  Chakraborty, Sutapa ^a   Roy, Madhumita ^a   Taraphdar, Amit K ^a   Bhattacharya, R K ^a  

^a CHITTARANJAN NATIONAL CANCER INSTITUTE   (India)

Author keywords

Apoptosis; Caspase activity; Cytotoxicity; DNA fragmentation; S. anacardium; T. racemosa; Tumour cells

Indexed keywords

ALCOHOL; ALKALOID; ARACHIS OIL; DNA FRAGMENT; FLUORESCENT DYE; GENOMIC DNA; PLANT EXTRACT; PROPIDIUM IODIDE; SEMECARPUS ANACARDIUM EXTRACT; TILIACORA RACEMOSA EXTRACT; UNCLASSIFIED DRUG;

ACUTE MYELOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; GEL ELECTROPHORESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYMPHOCYTE; MICROSCOPY; MYELOID LEUKEMIA; PLANT ROOT; TUMOR CELL LINE; TUMOR GROWTH; UTERINE CERVIX CARCINOMA;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FRUIT; HELA CELLS; HL-60 CELLS; HUMANS; K562 CELLS; MEDICINE, AYURVEDIC; PHYTOTHERAPY; PLANT EXTRACTS; PLANT OILS; PLANT ROOTS; PLANTS, MEDICINAL; SEMECARPUS;

ANACARDIUM; SEMECARPUS; SEMECARPUS ANACARDIUM;

EID: 4944232160     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1501     Document Type: Article

References (39)

1. Bollum FJ. 1968. Filter paper disc technique for assaying radioactive macromolecules. Meth Enzymol 12B: 169-173.
2. Chakrabarty S, Roy M, Hazra B, Bhattacharya RK, 2002. Induction of apoptosis in human cancer cell lines by diospyrin, a plant-derived bisnaphthoquinonoid, and its synthetic derivatives. Cancer Lett 188: 85-93.
3. Chitnis MP, Pathak MK, Kesava Rao KV. 1980. Antitumor activity of the extract of Semecarpus anacardium L. nuts in experimental tumor models. Indian J Exp Biol 18: 6-8.
4. Chopra RN, Nayar SL, Chopra IC. 1956. Glossary of Indian Medicinal Plants. Council of Scientific and Industrial Research: New Delhi.
5. Compton MM. 1992. Biochemical hallmark of apoptosis: internucleosomal degradation of the genome. Cancer Metastasis Rev 11: 105-109.
6. Ferguson LR. 1994. Antimutagens as cancer chemopreventive agents in the diet. Mutat Res 307: 395-410.
7. Gedam PH, Sampathkumaran PS, Sivasamban MA. 1974. Composition of bhilawanol from Semecarpus anacardium. Phytochemistry 13: 513-515.
8. Guha KP, Das PC, Mukherjee B, Mukherjee R, Juneau JP, Bhacca NS. 1976. Structure of tiliamosine: A diphenyl-bisbenzylisoquinoline alkaloid from Tiliacora racemosa. Tetrahedron Lett 26: 4241-4244.
9. Hambree JA, Chang CJ, McLaughlin JL, Pevck G, Cassidy JM. 1978. Anticancer activity of Semecarpus anacardium, 9KB active pentadecylcatechols. Lloydia 41: 441-443.
10. Hermann H, Lorenz H-M, Voll R, Grunke M, Woith W, Kalden JR. 1994. A rapid and simple method for the isolation of apoptotic DNA fragments. Nucl Acid Res 22: 5506-5507.
11. Huang M-T, Ferraro T. 1992. Phenolic compounds in food and cancer. In Phenolic Compounds in Food and their Effects on Health II, Huang M-T, Ho C-T, Lee CY (eds). American Chemical Society: Washington, DC, 8-34.
12. Ishartulla K, Ansari WH, Rahman W, Okigawa M, Kawano N. 1977. Biflavonoids from Semecarpus anacardium Linn. (Anacardiaceae). Indon J Chem 15B: 617-619.
13. Mishra S. 1990. In Avinaba-Bhaisajya-Kalpana-Vijnan. Chaukhamba Surabharati Prakashan: Varanasi, 247-248.
14. Murthy SSN. 1985. Jeediflavanone - a biflavanoid from Semecarpus anacardium. Phytochemistry 24: 1065-1069.
15. Nadkarni KM. 1993. Indian Materia Medica. Popular Prakashan: Bombay, 1119-1125.
16. Nicholson DW, Thornberry NA. 1997. Caspases: killer proteases. Trends Biochem Sci 22: 299-306.
17. Oren M. 1992. The involvement of oncogenes and tumor suppressor genes in the control of apoptosis. Cancer Metastat Rev 11: 141-148.
18. Prakasa Rao NS, Ramachandra Row H, Brown RT. 1973. Phenolic constituents of Semecarpus anacardium. Phytochemistry 12: 671-681.
19. Rastogi RP, Mehrotra BN. 1991. Compendium of Indian Medicinal Plants, Vol 2: Drug Research Perspective 1970-1979. Central Drug Research Institute: Lucknow, 369.
20. Ray AK, Mukhopadhyay G, Mitra SK, et al. 1989. (+)-N-methyltiliamosine: an alkaloid from Tiliacora racemosa. Phytochemistry 28: 675-676.
21. Ray AK, Mukhopadhyay G, Mitra SK, et al. 1990. A diphenylbisbenzylisoquinoline alkaloid from Tiliacora racemosa. Phytochemistry 29: 1020-1022.
22. Reed JC. 1994. Bcl-2 and the regulation of programmed cell death. J Cell Biol 124: 1-6.
23. Roy M, Chakrabarty S, Siddiqi M, Bhattacharya RK. 2002. Induction of apoptosis in tumor cells by natural phenolic compounds. Asian Pacific J Cancer Prev 3: 61-67.
24. Seal T, Mukherjee B. 1997. Pharmacological activities of bisbenzylisoquinoline alkaloids: a review. J Med Arom Plant Sci 19: 32-92.
25. Sharma PV. 1982. In Dravya-Gun-Vignan, Vol II. Chaukhamba Bharati Academi: Varanasi, 161-164.
26. Sharma PV. 1985. In Charak Samhita (critical notes), Vol 3. Chaukhamba Orientalia: Varanasi, 152-153.
27. Sharma PV. 1994. In Cakradatta (A Treatise of Principles and Practices of Ayurvedic Medicine). Chaukhamba Orientalia: Varanasi.
28. Silva GL, Chai H, Gupta MP, et al. 1995. Cytoytoxic biflavonoids from Selaginella wildenowii. Phytochemistry 40: 129-134.
29. Smit HF, Woerdenbag HJ, Singh RH, Meulenbeld GJ, Labadie RP, Zwaving JH. 1995. Ayurvedic herbal drugs with possible cytostatic activity. J Ethnopharmacol 47: 75-84.
30. Srikantha Murthy KR. 1995. In Astanga Hridayam, Vol II. Krishnadas Academy: Varanasi, 464.
31. Starvic B. 1994. Antimutagens and anticarcinogens in food. Food Chem Toxicol 32: 79-90.
32. Sun CM, Syu WJ, Huang YT, Chen CC, Ou JC. 1997. Selective cytotoxicity of ginkgetin from Selaginella inoellendroffii. J Nat Prod 60: 382-384.
33. Surh Y-J. 1998. Cancer chemoprevention by dietary phytochemicals: a mechanistic viewpoint. Cancer J 11: 6-10.
34. Taraphdar AK, Roy M, Bhattacharya RK. 2001. Natural products as inducers of apoptosis: Implication for cancer therapy and prevention. Curr Sci 80: 1387-1396.
35. Thornberry NA. 1997. The caspase family of cysteine proteases. Br Med Bull 53: 478-490.
36. Thornberry NA. 1998. Caspases: key mediators of apoptosis. Chem Biol 5: R97-R103.
37. Thornberry NA, Lazebnick Y. 1998. Caspases: enemies within. Science 281: 1312-1316.
38. Trikamji J. 1941. In Charak Samhita. Chaukhamba Sanskrit Sansthan: Varanasi, 97.
39. Warrier PK, Nambiar VPK, Ramankutty C. 1996. Indian Medicinal Plants, Vol 5 Orient Longman: New Delhi, 98-103.