Mechanism of interrupted saccades in patients with late-onset Tay-Sachs disease

Progress in Brain Research

Volumn 171, Issue , 2008, Pages 567-570

  Optican, Lance M ^a   Rucker, Janet C ^b   Keller, Edward L ^c   Leigh, R John ^d  

^a NATIONAL EYE INSTITUTE   (United States)

^b RUSH MEDICAL COLLEGE   (United States)

^c SMITH KETTLEWELL EYE RESEARCH INSTITUTE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

burst neurons; fastigial nucleus; latch circuit; omnipause neurons

Indexed keywords

BRAIN NERVE CELL; BRAIN STEM; CEREBELLUM CORTEX; CLINICAL ARTICLE; CONTROLLED STUDY; FASTIGIAL NUCLEUS; HUMAN; PRIORITY JOURNAL; REVIEW; SACCADIC EYE MOVEMENT; TAY SACHS DISEASE;

EID: 49349113485     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(08)00681-X     Document Type: Chapter

References (4)

1. Chern J., Beutler E., Kuhl W., Gilbert F., Mellman W.J., and Croce C.M. Characterization of heteropolymeric hexosaminidase A in human X mouse hybrid cells. Proc. Natl. Acad. Sci. U.S.A. 73 10 (1976) 3637-3640
2. Keller E.L., and Missal M. Shared brainstem pathways for saccades and smooth-pursuit eye movements. Ann. N.Y. Acad. Sci. 1004 (2003) 29-39
3. Optican L.M., and Quaia C. Distributed model of collicular and cerebellar function during saccades. Ann. N.Y. Acad. Sci. 956 (2002) 164-177
4. Rucker J.C., Shapiro B.E., Han Y.H., Kumar A.N., Garbutt S., Keller E.L., and Leigh R.J. Neuro-ophthalmology of late-onset Tay-Sachs disease (LOTS). Neurology 63 10 (2004) 1918-1926