Non-infectious causes of elevated procalcitonin and C-reactive protein serum levels in pediatric patients with hematologic and oncologic disorders

Supportive Care in Cancer

Volumn 16, Issue 9, 2008, Pages 1035-1040

  Dornbusch, Hans Jürgen ^a   Strenger, Volker ^a   Sovinz, Petra ^a   Lackner, Herwig ^a   Schwinger, Wolfgang ^a   Kerbl, Reinhold ^b   Urban, Christian ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b General Hospital of Leoben   (Austria)

Author keywords

CRP; Granulocyte transfusion; GvHD; Interleukin 2; Procalcitonin; T cell antibodies

Indexed keywords

ALEMTUZUMAB; C REACTIVE PROTEIN; INTERLEUKIN 2; PROCALCITONIN; T LYMPHOCYTE ANTIBODY;

ACUTE GRAFT VERSUS HOST DISEASE; ACUTE LYMPHOCYTIC LEUKEMIA; ACUTE MYELOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; CANCER IMMUNOTHERAPY; CHILD; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DISEASE MARKER; FEMALE; FEVER; GRAM NEGATIVE INFECTION; GRANULOCYTE TRANSFUSION; HEMATOLOGIC DISEASE; HUMAN; IMMUNE DEFICIENCY; INFANT; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; SEPSIS;

ADOLESCENT; ADULT; AGE FACTORS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CALCITONIN; CHILD; CHILD WELFARE; CHILD, PRESCHOOL; FEMALE; GRAFT VS HOST DISEASE; HEMATOLOGIC DISEASES; HEMATOLOGIC NEOPLASMS; HUMANS; INFANT; INTERLEUKIN-2; MALE; PROSPECTIVE STUDIES; PROTEIN PRECURSORS; TUMOR MARKERS, BIOLOGICAL;

EID: 49349107808     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00520-007-0381-1     Document Type: Article

References (28)

1. A Aouifi V Piriou O Bastien P Blanc H Bouvier R Evans M Celard F Vandenesch R Rousson JJ Lehot 2000 Usefulness of procalcitonin for diagnosis of infection in cardiac surgical patients Crit Care Med 28 9 3171 3176
2. NM Blijlevens JP Donnelly JF Meis MH De Keizer BE De Pauw 2000 Procalcitonin does not discriminate infection from inflammation after allogeneic bone marrow transplantation Clin Diagn Lab Immunol 7 6 889 892
3. M Christ-Crain D Jaccard-Stolz R Bingisser MM Gencay PR Huber M Tamm B Muller 2004 Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial Lancet 363 9409 600 607
4. M Christ-Crain B Müller 2005 Procalcitonin in bacterial infections-hype, hope, more or less Swiss Med Wkly 135 451 460
5. MG Dehne A Sablotzki A Hoffmann J Muhling FE Dietrich G Hempelmann 2002 Alterations of acute phase reaction and cytokine production in patients following severe burn injury Burns 28 6 535 542
6. HJ Dornbusch R Kerbl H Lackner KH Preisegger W Schwinger A Berghold C Urban 2000 Procalcitonin and C-reactive protein levels at the time of engraftment after stem cell transplantation Acta Chir Austriaca 32 Suppl 170 37
7. HJ Dornbusch V Strenger R Kerbl H Lackner W Schwinger P Sovinz C Urban 2003 Procalcitonin and C-reactive protein do not discriminate between febrile reaction to anti-lymphocyte antibodies and Gram-negative sepsis Bone Marrow Transplant 32 941 945
8. HJ Dornbusch V Strenger R Kerbl H Lackner W Schwinger P Sovinz C Urban 2005 Procalcitonin-a marker of invasive fungal infection Support Care Cancer 13 343 346
9. G Fleischhack I Kambeck D Cipic C Hasan U Bode 2000 Procalcitonin in paediatric cancer patients: its diagnostic relevance is superior to that of C-reactive protein, interleukin-6, interleukin-8, soluble interleukin-2 receptor and soluble tumour necrosis factor receptor II Br J Haematol 111 4 1093 102
10. LO Hansson L Lindquist 1997 C-reactive protein: its role in the diagnosis and follow-up of infectious diseases Curr Opin Infect Dis 10 196 201
11. WR Hayden 1994 Sepsis terminology in pediatrics J Pediatr 124 4 657 658
12. A Jimeno A Garcia-Velasco O del Val E Gonzalez-Billalabeitia S Hernando R Hernandez A Sanchez-Munoz A Lopez-Martin I Duran L Robles H Cortes-Funes L Paz-Ares 2004 Assessment of procalcitonin as a diagnostic and prognostic marker in patients with solid tumors and febrile neutropenia Cancer 100 11 2462 2469
13. E Legouffe C Rodriguez MC Picot B Richard B Klein JF Rossi T Commes 1998 C-reactive protein serum level is a valuable and simple prognostic marker in non-Hodgkin lymphoma Leuk Lymphoma 31 351 357
14. S Mousset S Hermann SA Klein H Bialleck M Duchscherer B Bomke B Wassmann A Boehme D Hoelzer H Martin 2005 Prophylactic and interventional granulocyte transfusions in patients with haematological malignancies and life-threatening infections during neutropenia Ann Hematol 84 11 734 741 electronically prepublished 11 Jun 2005
15. B Müller J White E Nylen R Snider K Becker J Habener 2001 Ubiquitous expression of the calcitonin-1 gene in multiple tissues in response to sepsis J Clin Endocrinol Metab 86 396 404
16. Y Okada H Minakami T Tomomasa M Kato Y Inoue K Kozawa H Kimura A Morikawa 2004 Serum procalcitonin concentration in patients with Kawasaki disease J Infect 48 2 199 205
17. L Persson B Soderquist P Engervall T Vikerfors LO Hansson U Tidefelt 2005 Assessment of systemic inflammation markers to differentiate a stable from a deteriorating course in patients with febrile neutropenia Eur J Haematol 74 4 297 303
18. M Pihusch R Pihusch P Fraunberger V Pihusch R Andreesen HJ Kolb E Holler 2006 Evaluation of C-reactive protein, interleukin-6, and procalcitonin levels in allogeneic hematopoietic stem cell recipients Eur J Haematol 76 2 93 101
19. D Przepiorka D Weisdorf P Martin HG Klingemann P Beatty J Hows ED Thomas 1995 1994 Consensus conference on acute GvHD grading Bone Marrow Transplant 15 6 825 828
20. R Sabat C Hoflich WD Docke M Oppert F Kern B Windrich C Rosenberger J Kaden HD Volk P Reinke 2001 Massive elevation of procalcitonin plasma levels in the absence of infection in kidney transplant patients treated with pan-T-cell antibodies Intensive Care Med 27 6 987 991
21. Y Saijo N Kiyota Y Kawasaki Y Miyazaki J Kashimura M Fukuda R Kishi 2004 Relationship between C-reactive protein and visceral adipose tissue in healthy Japanese subjects Diabetes Obes Metab 6 4 249 258
22. W Schwinger V Klass M Benesch HJ Dornbusch P Sovinz A Moser G Schwanzer C Urban 2005 Feasibility of high-dose interleukin-2 in heavily pretreated pediatric cancer patients Ann Oncol 16 1199 1206
23. L Simon F Gauvin DK Amre P Saint-Louis J Lacroix 2004 Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis Clin Infect Dis 39 206 217
24. NV Sipsas GP Bodey DP Kontoyiannis 2005 Perspectives for the management of febrile neutropenic patients with cancer in the 21st century Cancer 103 6 1103 1113
25. P Toikka K Irjala T Juven R Virkki J Mertsola M Leinonen O Ruuskanen 2000 Serum procalcitonin, C-reactive protein and interleukin-6 for distinguishing bacterial and viral pneumonia in children Pediatr Infect Dis J 19 7 598 602
26. AMC Van Rossum RW Wulkan AM Oudesluys-Murphy 2004 Procalcitonin as an early marker of infection in neonates and children Lancet Infect Dis 4 620 630
27. MG Wing M Thibault J Greenwood RM Smith G Hale J Isaacs H Waldmann PJ Lachmann A Compston 1996 Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FCgammaRIII) and CD11a/CD18 (LFA-1) on NK cells J Clin Invest 98 2819 2826
28. HK Yip CL Hang CY Fang YK Hsieh CH Yang WC Hung CJ Wu 2005 Level of high-sensitivity C-reactive protein is predictive of 30-day outcomes in patients with acute myocardial infarction undergoing primary coronary intervention Chest 127 3 803 808