Pathways to ANCA production: From differentiation of dendritic cells by proteinase 3 to B lymphocyte maturation in Wegener's granuloma

Clinical Reviews in Allergy and Immunology

Volumn 34, Issue 3, 2008, Pages 300-306

  Csernok, Elena ^a   Moosig, Frank ^a   Gross, Wolgang L ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

ANCA; Proteinase 3; Wegener's granulomatosis

Indexed keywords

MYELOBLASTIN; MYELOPEROXIDASE; NEUTROPHIL CYTOPLASMIC ANTIBODY;

ANCA ASSOCIATED VASCULITIS; APOPTOSIS; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL MATURATION; HUMAN; IN VIVO STUDY; INFECTION; NONHUMAN; PHENOTYPE; REVIEW; WEGENER GRANULOMATOSIS;

ANIMALS; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; APOPTOSIS; B-LYMPHOCYTES; CELL DIFFERENTIATION; DENDRITIC CELLS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFECTION; MYELOBLASTIN; NEUTROPHILS; PEROXIDASE; RECEPTOR, PAR-2; VASCULITIS; WEGENER GRANULOMATOSIS;

EID: 49349106273     PISSN: 10800549     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12016-007-8056-8     Document Type: Review

References (34)

1. WL Gross E Csernok WH Schmitt 1991 Antineutrophil cytoplasmic autoantibodies: immunobiological aspects Klin Wochenschr 69 558 556
2. P Jagiello P Aries L Arning 2005 The PTPN22 620W allele is a risk factor for Wegener's granulomatosis Arthritis Rheum 52 4039 4043
3. YH Lee YH Rho SJ Choi 2007 The PTPN22 C1858T functional polymorphism and autoimmune diseases-a meta-analysis Rheumatology (Oxford) 46 49 56
4. KM Kaufman JA Kelly BJ Herring 2006 Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus Arthritis Rheum 54 2533 2540
5. AB Begovich VE Carlton LA Honigberg 2004 A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis Am J Hum Genet 75 330 337
6. GD Nuyts E Van Vlem A De Vos 1995 Wegener granulomatosis is associated to exposure to silicon compounds: a case-control study Nephrol Dial Transplant 10 1162 1165
7. CA Stegeman JW Tervaert WJ Sluiter 1994 Association of chronic nasal carriage of Staphylococcus aureus and higher relapse rates in Wegener granulomatosis Ann Intern Med 120 12 17
8. H Schultz 2007 From infection to autoimmunity: a new model for induction of ANCA against the bactericidal/permeability increasing protein (BPI) Autoimmun Rev 6 223 227
9. HK Choi P Lamprecht JL Niles 2000 Subacute bacterial endocarditis with positive cytoplasmic antineutrophil cytoplasmic antibodies and anti-proteinase 3 antibodies Arthritis Rheum 43 226 231
10. WF Pendergraft 3rd GA Preston RR Shah 2004 Autoimmunity is triggered by cPR-3(105-201), a protein complementary to human autoantigen proteinase-3 Nat Med 10 72 79
11. A Mueller A Trabandt K Gloeckner-Hofmann 2000 Localized Wegener's granulomatosis: predominance of CD26 and IFN-gamma expression J Pathol 192 113 120
12. J Voswinkel A Mueller JA Kraemer 2006 B lymphocyte maturation in Wegener's granulomatosis: a comparative analysis of VH genes from endonasal lesions Ann Rheum Dis 65 859 864
13. P Lamprecht WL Gross 2007 Current knowledge on cellular interactions in the WG-granuloma Clin Exp Rheumatol 25 S49 S51
14. PH Plotz 2003 The autoantibody repertoire: searching for order Nat Rev Immunol 3 73 78
15. E Csernok M Ai WL Gross D Wicklein 2006 Wegener autoantigen induces maturation of dendritic cells and licenses them for Th1 priming via the protease-activated receptor-2 pathway Blood 107 4440 4448
16. PM Aries P Lamprecht WL Gross 2006 Rituximab in refractory Wegener's granulomatosis: favorable or not? Am J Respir Crit Care Med 173 815 816
17. B Hellmich P Lamprecht WL Gross 2006 Advances in the therapy of Wegener's granulomatosis Curr Opin Rheumatol 18 25 32
18. C Geffriaud-Ricouard LH Noel D Chauveau 1993 Clinical spectrum associated with ANCA of defined antigen specificities in 98 selected patients Clin Nephrol 39 125 136
19. U Schoenermarck P Lamprecht E Csernok 2001 Prevalence and spectrum of rheumatic diseases associated with proteinase 3-antineutrophil cytoplasmic antibodies (ANCA) and myeloperoxidase-ANCA Rheumatology (Oxford) 40 178 184
20. HA Hauer IM Bajema HC van Houwelingen 2002 Renal histology in ANCA-associated vasculitis: differences between diagnostic and serologic subgroups Kidney Int 61 80 89
21. S Michlewska A McColl AG Rossi 2007 Clearance of dying cells and autoimmunity Autoimmunity 40 267 273
22. WD Duan-Porter L Casciola-Rosen A Rosen 2005 Autoantigens: the critical partner in initiating and propagating systemic autoimmunity Ann N Y Acad Sci 1062 127 136
23. HM Gilligan B Bredy HR Brady 1996 Antineutrophil cytoplasmic autoantibodies interact with primary granule constituents on the surface of apoptotic neutrophils in the absence of neutrophil priming J Exp Med 184 2231 2241
24. F Moosig E Csernok G Kumanovics 2000 Opsonization of apoptotic neutrophils by anti-neutrophil cytoplasmic antibodies (ANCA) leads to enhanced uptake by macrophages and increased release of tumour necrosis factor-alpha (TNF-alpha) Clin Exp Immunol 122 499 503
25. L Harper Y Ren J Savill D Adu 2000 Antineutrophil cytoplasmic antibodies induce reactive oxygen-dependent dysregulation of primed neutrophil apoptosis and clearance by macrophages Am J Pathol 157 211 220
26. R Kettritz J Scheumann Y Xu 2002 TNF-alpha-accelerated apoptosis abrogates ANCA-mediated neutrophil respiratory burst by a caspase-dependent mechanism Kidney Int 61 502 515
27. YC Patry DC Trewick M Gregoire 2001 Rats injected with syngenic rat apoptotic neutrophils develop antineutrophil cytoplasmic antibodies J Am Soc Nephrol 12 1764 1768
28. CG Kallenberg P Heeringa CA Stegeman 2006 Mechanisms of disease: pathogenesis and treatment of ANCA-associated vasculitides Nat Clin Pract Rheumatol 2 661 670
29. 2 in myeloperoxidase- immunized rats leads to necrotizing vasculitis in the lungs and gut Am J Pathol 151 131 140
30. JM Harper S Thiru CM Lockwood 1998 Myeloperoxidase autoantibodies distinguish vasculitis mediated by anti-neutrophil cytoplasm antibodies from immune complex disease in MRL/Mp-lpr/lpr mice: a spontaneous model for human microscopic angiitis Eur J Immunol 28 2217 2226
31. Y Tomer B Gilburd M Blank 1995 Characterization of biologically active antineutrophil cytoplasmic antibodies induced in mice. Pathogenetic role in experimental vasculitis Arthritis Rheum 38 1375 1381
32. O Wiesner RD Litwiller AM Hummel 2005 Differences between human proteinase 3 and neutrophil elastase and their murine homologues are relevant for murine model experiments FEBS Lett 579 5305 5312
33. H Xiao P Heeringa P Hu 2002 Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice J Clin Invest 110 955 963
34. MA Little CL Smyth R Yadav L Ambrose HT Coock S Nourshargh CD Pusey 2005 Antineutrophil cytoplasm antibodies directed against myeloperoxidase augment leukocyte-microvascular interactions in vivo Blood 106 86 2050 2058