Tissue engineering a complete vaginal replacement from a small biopsy of autologous tissue

Transplantation

Volumn 86, Issue 2, 2008, Pages 208-214

  De Philippo, Roger E ^a,b   Bishop, Colin E ^a   Filho, Luiz Freitas ^a,c   Yoo, James J ^a   Atala, Anthony ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Hospital Infantil Darcy Vargas   (Brazil)

Author keywords

Regenerative medicine; Replacement organs; Tissue engineering; Vagina

Indexed keywords

PHENTOLAMINE; PHENYLEPHRINE; COLLAGEN; ELASTIN; POLYMER;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOTRANSPLANTATION; BIOPSY; CELL EXPANSION; CONTROLLED STUDY; ELECTROSTIMULATION; ESOPHAGUS STRICTURE; FEMALE; HISTOLOGY; NONHUMAN; PRIORITY JOURNAL; RABBIT; RADIOGRAPHY; TISSUE ENGINEERING; TISSUE GRAFT; TISSUE REACTION; VAGINA; VAGINA EPITHELIUM; VAGINA RECONSTRUCTION; ANIMAL; BIOMECHANICS; CHEMISTRY; CULTURE TECHNIQUE; CYTOLOGY; IMMUNOHISTOCHEMISTRY; INSTRUMENTATION; METABOLISM; METHODOLOGY; TENSILE STRENGTH; TIME; VAGINA DISEASE;

ANIMALS; BIOMECHANICS; BIOPSY; CELL CULTURE TECHNIQUES; COLLAGEN; ELASTIN; FEMALE; IMMUNOHISTOCHEMISTRY; POLYMERS; RABBITS; TENSILE STRENGTH; TIME FACTORS; TISSUE ENGINEERING; VAGINA; VAGINAL DISEASES;

EID: 49249108895     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31817f1686     Document Type: Article

References (13)

1. Wefer J, Sekido N, Sievert KD, et al. Homologous acellular matrix graft for vaginal repair in rats: A pilot study for a new reconstructive approach. World J Urol 2002; 20: 260.
2. Atala A, Bauer SB, Soker S, et al. Tissue-engineered autologous bladders for patients needing cystoplasty. Lancet 2006; 367: 1241.
3. Hohlfeld J, de Buys Roessingh A, Hirt-Burri N, et al. Tissue engineered fetal skin constructs for paediatric burns. Lancet 2005; 366: 840.
4. Hollander AP, Dickinson SC, Sims TJ, et al. Maturation of tissue engineered cartilage implanted in injured and osteoarthritic human knees. Tissue Eng 2006; 12: 1787.
5. Kershen RT, Fefer SD, Atala A. Tissue-engineered therapies for the treatment of urinary incontinence and vesicoureteral reflux. World J Urol 2000; 18: 51.
6. De Filippo RE, Yoo JJ, Atala A. Engineering of vaginal tissue in vivo. Tissue Eng 2003; 9: 301.
7. Cilento BG, Freeman MR, Schneck FX, et al. Phenotypic and cytoge-netic characterization of human bladder urothelia expanded in vitro. J Urol 1994; 152(2 Pt 2): 665.
8. Horan PK, Slezak SE. Stable cell membrane labelling. Nature 1989; 340: 167.
9. Dahms SE, Piechota HJ, Dahiya R, et al. Composition and biomechani-cal properties of the bladder acellular matrix graft: Comparative analysis in rat, pig and human. Br J Urol 1998; 82: 411.
10. Goh JT. Biomechanical and biochemical assessments for pelvic organ prolapse. Curr Opin Obstet Gynecol 2003; 15: 391.
11. Petros PE, Ulmsten UI. An integral theory of female urinary incontinence. Experimental and clinical considerations. Acta Obstet Gynecol Scand Suppl 1990; 153: 7.
12. Rosso F, Marino G, Giordano A, et al. Smart materials as scaffolds for tissue engineering. J Cell Physiol 2005; 203: 465.
13. Soker S, Machado M, Atala A. Systems for therapeutic angiogenesis in tissue engineering. World J Urol 2000; 18: 10.