Predicting positive and negative treatment responses to stimulants with brain spect imaging

Journal of Psychoactive Drugs

Volumn 40, Issue 2, 2008, Pages 131-138

  Amen, Daniel G ^a   Hanks, Chris ^b   Prunella, Jill ^b  

^a Amen Clinics Inc   (United States)

^b Institute for the Study of ADHD   (United States)

Author keywords

ADHD; CNS stimulant; Neuroimaging; SPECT; Treatment response

Indexed keywords

CENTRAL STIMULANT AGENT; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M;

ADULT; ANXIETY; ARTICLE; ATTENTION DEFICIT DISORDER; BRAIN BLOOD FLOW; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; OUTCOME ASSESSMENT; PREDICTION; PREFRONTAL CORTEX; SENSITIVITY AND SPECIFICITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TREATMENT OUTCOME;

EID: 49149131587     PISSN: 02791072     EISSN: 21599777     Source Type: Journal    
DOI: 10.1080/02791072.2008.10400622     Document Type: Article

References (29)

1. Biederman, J.; Quinn, D.; Weiss, M.; Markabi, S.; Weidenman, M.; Edson, K.; Karlsson, G.; Pohlmann, H. & Wigal, S. 2003. Efficacy and safety of Ritalin LA, a new, once daily, extended-release dosage form of methylphenidate, in children with attention deficit hyperactivity disorder. Paediatric Drugs 5 (12): 833-41.
2. Bruera, E.; Driver, L.; Barnes, E.A.; Willey, J.; Shen, L.; Palmer, J.L. & Escalante, C. 2003. Patient-controlled methylphenidate for the managementof fatigue in patients with advanced cancer, a preliminary report. Journal of Clinical Oncology 21: 4439-43.
3. Challman, T.D. & Lipsky, J.J. 2000. Methylphenidate: its pharmacology and uses. Mayo Clinic Proceedings 75 (7): 711-21.
4. Cherland, E. & Fitzpatrick, R. 1999. Psychotic side effects of psychostimulants: A 5-year review. Canadian Journal of Psychiatry 44: 811-13.
5. Conca, A.; Swoboda, E.; Konig, P.; Koppi, S.; Beraus, W.; Kunz, A.; Fritzche, H. & Weiss, P. 2000. Clinical impacts of single transcranial magnetic stimulation (sTMS) as an add-on therapy in severely depressed patients under SSRI treatment. Human Psychopharmacology 15 (6): 429-38.
6. Fletcher, J.M.; Shaywitz, B.A. & Shaywitz, S.E. 1994. Attention as a process and as a disorder. In: G.R. Lyon (Ed.) Frames ofReferencefor the Assessment of Learning Disabilities, New Views on Measurement Issues. Baltimore, MD: Paul H Brookes.
7. Goforth, H.W.; Konopka, L.; Primeau, M.; Ruth, A.; O'Donnell, K.; Patel, R.; Poprawski, T.; Shirazi, P. & Rao, M. 2004. Quantitative electroencephalography in frontotemporal dementia with methylphenidate response, a case study. Clinical EEG Neuroscience 35: 108-11.
8. Greenhill, L.L.; Pliszka, S.; Dulcan, M.K.; Bernet, W.; Arnold, V.; Beitchman, J.; Benson, R.S.; Bukstein, O.; Kinlan, J.; McClellan, J.; Rue, D.; Shaw, J.A. & Stock, S. 2002. Practice parameters for the use of stimulant medications in the treatment of children, adolescents, and adults. Journal of the American Academy of Child and Adolescent Psychiatry 41 (Suppl 2): 26S-49S.
9. Gualtieri, C.T. & Evans, R.W. 1988. Stimulant treatment for the neurobehavioral sequelae of traumatic brain injury. Brain Injury 2: 273-90.
10. Jadad, A.R.; Boyle, M.; Cunningham, C.; Kim, M. & Schachar, R. 1999. Treatment of Attention-Deficit/Hyperactivity Disorder. Evidence Report/Technology Assessment No. ll. Rockville, Md: Agency for Healthcare Research and Quality.
11. Kajs-Wyllie, M. 2002. Ritalin revisited: Does it really help in neurological injury? Journal of Neuroscience Nursing 34 (6): 303-13.
12. Kittur, S. & Hauser, P. 1999. Improvement of sleep and behavior by methylphenidate in Alzheimer’s disease. American Journal of Psychiatry 156: 1116-7.
13. Koenig, H.G.; Shelp, F.; Goli, V.; Cohen, H.J. & Blazer, D.G. l989. Survival and health care utilization in elderly medical inpatients with major depression. Journal of the American Geriatric Society 37: 599-607.
14. Kugaya, A.; Sanacora, G.; Staley, J.K.; Malison, R.T.; Bozkurt, A.; Khan, S.; Anand, A.; Van Dyck, C.H.; Baldwin, R.M.; Seibyl, J.P.; Cheey, D. & Innis, R.B. 2004. Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors. Biological Psychiatry 56 (7): 497-502.
15. Mai, J.K.; Assheur, J. & Paxinos, G. 1997. Atlas of the Human Brain. San Diego: Academic Press.
16. Mega, M.S.; Dinov, J.D.; Lee, L.; O'Connor, S.M.; Masterman, D.M.; Wilen, B.; Mishkin, F.; Toga, A.W. & Cummings, J.L. 2000 Orbital and dorsolateral frontal perfusion defect associated with behavioral response to cholinesterase inhibitor therapy in Alzheimer's disease. Journal of Neuropsychiatry and Clinical Neuroscience 2 (2): 209-18.
17. Morris, P.L.; Robinson, R.G.; Andrzejewski, P., Samuels, J. & Price, T.R. 1993. Association of depression with 10-year postroke mortality. American Journal of Psychiatry 150: 124-29.
18. Murphy, K. & Barkley, R.A. 1996. Prevalence of DSM-IV symptoms of ADHD in adult licensed drivers: Implications for clinical diagnosis. Journal of Attention Disorders 1: 147-61.
19. Navarro, V.; Gasto, C.; Lomena, F.; Torres, X.; Mateos, J.J.; Portella, M.J.; Masana, G. & Marcos, T.2004.Prognostic value offrontal functional neuroimaging in late-onset severe major depression. British Journal of Psychiatry 184: 306-11.
20. Pollmann, S. 2004. Anterior prefrontal cortex contributions to attention control. Experimental Psychology 51 (4): 270-78.
21. Post, R.M.; Speer, A.M.; Hough, C.J. & Xing, G. 2003 Neurobiology of bipolar illness: Implications for future study and therapeutics. Annals of Clinical Psychiatry 15 (2): 85-94.
22. Rothman, R.B.; Partilla, J.S.; Baumann, M.H.; Dersch, C.M.; Carroll, F.I. & Rice, K.C. 2000. Neurochemical neutralization of methamphetamine with high-affinity nonselective inhibitors of biogenic amine transporters: A pharmacological strategy for treating stimulant abuse. Synapse 35 (3): 223-27.
23. Santosh, P.J. & Taylor, E. 2000. Stimulant drugs. European Child & Adolescent Psychiatry 9: 127-43.
24. Shafritz, KM.; Marchione, K.E.; Gore, J.C.; Shaywitz, S.E. & Shaywitz, B.A. 2004. The effects of methylphenidate on neural systems of attention in Attention Deficit Hyperactivity Disorder. American Journal of Psychiatry 161: 1990-97.
25. Shaw, P.; Gornick, B.S.; Lerch, J.; Addington, A.; Seal, J.; Greenstein, D.; Sharp, W.; Evans, A.; Giedd, J.N.; Castellanos, F.X. & Rapoport, M.D. 2007. Polymorphisms of the dopamine D4 receptor, clinical outcome, and cortical structure in attention-deficit/hyperactivity disorder. Archives of General Psychiatry 648: 921-31.
26. Shaywitz, S.E.; Fletcher, J.M. & Shaywitz, B.A. 1994. Issues in the definition and classification of attention deficit disorder. Topics in Language Disorders 14: l-25.
27. Spinella, M. 2004. Neurobehavioral correlates of impulsivity: Evidence of prefrontal involvement. International Journal of Neuroscience 114 (1): 95-104.
28. Todd, R.D. & Botteron, K.N. 2001. Is attention-deficit/hyperactivity disorder an energy deficiency syndrome? Biological Psychiatry 50 (3): 151-58.
29. Wolraich, M.L.; Hannah, J.N.; Pinnock, T.Y.; Baumgaertel, A. & Brown, J. 1996. Comparison of diagnostic criteria for attention-deficit hyperactivity disorder in a county-wide sample. Journal of the American Academy of Child and Adolescent Psychiatry 35: 319-24.