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Volumn 16, Issue 16, 2008, Pages 7552-7560

Structure-activity relationship studies on a novel class of antiproliferative agents derived from Lavendustin A. Part I: Ring A modifications

(2) Nussbaumer, Peter a Winiski, Anthony P a

a Novartis Institutes for Biomedical Research (Austria)

Author keywords

Antiproliferative; Inhibitors; Structure activity relationship; Tubulin

Indexed keywords

5 [2 (2 ACETYL 5 METHOXYPHENYL)ETHYL] 2 HYDROXYBENZOIC ACID METHYL ESTER; 5 [2 (2 ETHOXY 5 METHOXYPHENYL)ETHYL] 2 HYDROXYBENZOIC ACID METHYL ESTER; 5 [2 (2 ETHYL 5 METHOXYPHENYL)ETHYL] 2 HYDROXYBENZOIC ACID METHYL ESTER; 5 [2 (2,5 DIACETOXYPHENYL)ETHYL] 2 HYDROXYBENZOIC ACID METHYL ESTER; 5 [2 (3,4,5 TRIMETHOXYPHENYL)ETHYL] 2 HYDROXYBENZOIC ACID METHYL ESTER; 5 [2 (5 ACETYL 2 METHOXYPHENYL)ETHYL] 2 HYDROXYBENZOIC ACID METHYL ESTER; 5 [2 (5 DIMETHYLAMINO 2 METHOXYPHENYL)ETHYL] 2 HYDROXYBENZOIC ACID METHYL ESTER; ANTIMITOTIC AGENT; LAVENDUSTIN A; LAVENDUSTIN A DERIVATIVE; SDZ LAP 977; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CELL PROLIFERATION; DRUG ACTIVITY; DRUG EFFICACY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROGENATION; IN VITRO STUDY; POLYMERIZATION; STRUCTURE ACTIVITY RELATION; WITTIG REACTION;

BINDING SITES; CELL GROWTH PROCESSES; CELL LINE; COLCHICINE; HUMANS; KERATINOCYTES; MICROSCOPY, FLUORESCENCE; MICROTUBULES; MITOSIS; PHENOLS; PROTEIN KINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

EID: 49149113872 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2008.07.039 Document Type: Article

Times cited : (2)

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