Chromosomal instability in fallopian tube precursor lesions of serous carcinoma and frequent monoclonality of synchronous ovarian and fallopian tube mucosal serous carcinoma

Gynecologic Oncology

Volumn 110, Issue 3, 2008, Pages 408-417

  Salvador, Shannon ^a   Rempel, Allan ^a   Soslow, Robert A ^b   Gilks, Blake ^a   Huntsman, David ^a,c   Miller, Dianne ^d  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c VANCOUVER COASTAL HEALTH RESEARCH INSTITUTE   (Canada)

^d VANCOUVER COASTAL HEALTH   (Canada)

Author keywords

Fallopian tube carcinoma; O">rigin of disease; Ovarian carcinoma; Pelvic serous carcinoma

Indexed keywords

KI 67 ANTIGEN; PROTEIN P53;

ARTICLE; CANCER DIAGNOSIS; CANCER GROWTH; CANCER RISK; CANCER STAGING; CELL STRUCTURE; CHROMOSOMAL INSTABILITY; CHROMOSOME NUMBER; CLINICAL ARTICLE; DYSPLASIA; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INVASIVE CARCINOMA; MUCINOUS CARCINOMA; OVARY CARCINOMA; PRIORITY JOURNAL; SALPINGECTOMY; UTERINE TUBE TUMOR;

CHROMOSOMAL INSTABILITY; CYSTADENOCARCINOMA, SEROUS; FALLOPIAN TUBE NEOPLASMS; FEMALE; GENE DOSAGE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KI-67 ANTIGEN; NEOPLASM STAGING; NEOPLASMS, MULTIPLE PRIMARY; OVARIAN NEOPLASMS; OVARIECTOMY; PRECANCEROUS CONDITIONS; PROSPECTIVE STUDIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 49149112132     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2008.05.010     Document Type: Article

References (42)

1. Rosenblatt K.A., Weiss N.S., and Schwartz S.M. Incidence of malignant fallopian tube tumors. Gynecol Oncol 35 2 (1989) 236-239
2. Alvarado-Cabrero I., Young R.H., Vamvakas E.C., and Scully R.E. Carcinoma of the fallopian tube: a clinicopathological study of 105 cases with observations on staging and prognostic factors. Gynecol Oncol 72 3 (1999) 367-379
3. Hu C.Y., Taylor M.L., and Hertig A. Primary carcinoma of the fallopian tube. Am J Obstet Gynecol 59 1 (1950) 58-67
4. Sedlis A. Primary carcinoma of the fallopian tube. Obstet Gynecol Surv 16 (1961) 209-226
5. Yoonessi M. Carcinoma of the fallopian tube. Obstet Gynecol Surv 34 4 (1979) 257-270
6. Benedet J.L., Bender H., Jones III H., Ngan H.Y., and Pecorelli S. FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO Committee on Gynecologic Oncology. Int J Gynaecol Obstet 70 2 (2000) 209-262
7. Doran A. Tumours of the ovary, fallopian tube, and broad ligament (1884), Smith, Elder, & Co., London
8. Woolas R., Jacobs I., Davies A.P., Leake J., Brown C., Grudzinskas J.G., et al. What is the true incidence of primary fallopian tube carcinoma?. Int J Gynecol Cancer 4 6 (1994) 384-388
9. Clayton N.L., Jaaback K.S., and Hirschowitz L. Primary fallopian tube carcinoma - the experience of a UK cancer centre and a review of the literature. J Obstet Gynaecol 25 7 (2005) 694-702
10. Powell C.B., Kenley E., Chen L.M., Crawford B., McLennan J., Zaloudek C., et al. Risk-reducing salpingo-oophorectomy in BRCA mutation carriers: role of serial sectioning in the detection of occult malignancy. J Clin Oncol 23 1 (2005) 127-132
11. Medeiros F., Muto M.G., Lee Y., Elvin J.A., Callahan M.J., Feltmate C., et al. The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome. Am J Surg Pathol 30 2 (2006) 230-236
12. Finch A., Shaw P., Rosen B., Murphy J., Narod S.A., and Colgan T.J. Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers. Gynecol Oncol 100 1 (2006) 58-64
13. Piek J.M., van Diest P.J., Zweemer R.P., Jansen J.W., Poort-Keesom R.J., Menko F.H., et al. Dysplastic changes in prophylactically removed Fallopian tubes of women predisposed to developing ovarian cancer. J Pathol 195 4 (2001) 451-456
14. Jarboe E.M.D., Folkins A., Nucci M.R., Kindelberger D., Drapkin R., Miron A., et al. Serous carcinogenesis in the fallopian tube: a descriptive classification. Int J Gynecol Pathol 27 1 (2008) 1-9
15. Alkushi A., Clarke B.A., Akbari M., Makkretsov N., Lim P., Miller D., et al. Identification of prognostically relevant and reproducible subsets of endometrial adenocarcinoma based on clustering analysis of immunostaining data. Mod Pathol 20 11 (2007) 1156-1165
16. Alkushi A., Lim P., Coldman A., Huntsman D., Miller D., and Gilks B. Interpretation of p53 immunoreactivity in endometrial carcinoma: establishing a clinically relevant cut-off level. Int J Gynecol Pathol 23 2 (2004) 129-137
17. Havrilesky L., Darcy M., Hamdan H., Priore R.L., Leon J., Bell J., et al. Prognostic significance of p53 mutation and p53 overexpression in advanced epithelial ovarian cancer: a Gynecologic Oncology Group Study. J Clin Oncol 21 20 (2003) 3814-3825
18. Sneige N., Liu B., Yin G., Gong Y., and Arun B.K. Correlation of cytologic findings and chromosomal instability detected by fluorescence in situ hybridization in breast fine-needle aspiration specimens from women at high risk for breast cancer. Mod Pathol 19 5 (2006) 622-629
19. Al-Hussaini M., Stockman A., Foster H., and McCluggage W.G. WT-1 assists in distinguishing ovarian from uterine serous carcinoma and in distinguishing between serous and endometrioid ovarian carcinoma. Histopathology 44 2 (2004) 109-115
20. Fleming J.S., Beaugie C.R., Haviv I., Chenevix-Trench G., and Tan O.L. Incessant ovulation, inflammation and epithelial ovarian carcinogenesis: revisiting old hypotheses. Mol Cell Endocrinol 247 1-2 (2006) 4-21
21. Cramer D.W., and Welch W.R. Determinants of ovarian cancer risk. II. Inferences regarding pathogenesis. J Natl Cancer Inst 71 4 (1983) 717-721
22. Dubeau L. The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: does the emperor have no clothes?. Gynecol Oncol 72 3 (1999) 437-442
23. Crum C.P., Drapkin R., Miron A., Ince T.A., Muto M., Kindelberger D.W., et al. The distal fallopian tube: a new model for pelvic serous carcinogenesis. Curr Opin Obstet Gynecol 19 1 (2007) 3-9
24. Bowen N.J., Logani S., Dickerson E.B., Kapa L.B., Akhtar M., Benigno B.B., et al. Emerging roles for PAX8 in ovarian cancer and endosalpingeal development. Gynecol Oncol 104 2 (2007) 331-337
25. Marquez R.T., Baggerly K.A., Patterson A.P., Liu J., Broaddus R., Frumovitz M., et al. Patterns of gene expression in different histotypes of epithelial ovarian cancer correlate with those in normal fallopian tube, endometrium, and colon. Clin Cancer Res 11 17 (2005) 6116-6126
26. Jansen R.P. Endocrine response in the fallopian tube. Endocr Rev 5 4 (1984) 525-551
27. Piek J.M., Kenemans P., and Verheijen R.H. Intraperitoneal serous adenocarcinoma: a critical appraisal of three hypotheses on its cause. Am J Obstet Gynecol 191 3 (2004) 718-732
28. Kindelberger D.W., Lee Y., Miron A., Hirsch M.S., Feltmate C., Medeiros F., et al. Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationship. Am J Surg Pathol 31 2 (2007) 161-169
29. Young R.H., Gilks C.B., and Scully R.E. Mucinous tumors of the appendix associated with mucinous tumors of the ovary and pseudomyxoma peritonei. A clinicopathological analysis of 22 cases supporting an origin in the appendix. Am J Surg Pathol 15 5 (1991) 415-429
30. Elishaev E., Gilks C.B., Miller D., Srodon M., Kurman R.J., and Ronnett B.M. Synchronous and metachronous endocervical and ovarian neoplasms: evidence supporting interpretation of the ovarian neoplasms as metastatic endocervical adenocarcinomas simulating primary ovarian surface epithelial neoplasms. Am J Surg Pathol 29 3 (2005) 281-294
31. Mok C.H., Tsao S.W., Knapp R.C., Fishbaugh P.M., and Lau C.C. Unifocal origin of advanced human epithelial ovarian cancers. Cancer Res 52 18 (1992) 5119-5122
32. Lee Y., Miron A., Drapkin R., Nucci M.R., Medeiros F., Saleemuddin A., et al. A candidate precursor to serous carcinoma that originates in the distal fallopian tube. J Pathol 211 1 (2007) 26-35
33. Baergen R.N., Warren C.D., Isacson C., and Ellenson L.H. Early uterine serous carcinoma: clonal origin of extrauterine disease. Int J Gynecol Pathol 20 3 (2001) 214-219
34. Muto M.G., Welch W.R., Mok S.C., Bandera C.A., Fishbaugh P.M., Tsao S.W., et al. Evidence for a multifocal origin of papillary serous carcinoma of the peritoneum. Cancer Res 55 3 (1995) 490-492
35. Nishimura M., Wakabayashi M., Hashimoto T., Shibata J., Ueyama H., Ebina M., et al. Papillary serous carcinoma of the peritoneum: analysis of clonality of peritoneal tumors. J Gastroenterol 35 7 (2000) 540-547
36. Chin K., de Solorzano C.O., Knowles D., Jones A., Chou W., Rodriguez E.G., et al. In situ analyses of genome instability in breast cancer. Nat Genet 36 9 (2004) 984-988
37. Press JZ, DeLuca A, Boyd N, Young S, Troussard A, Ridge Y, et al. Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities. Int J Gynaecol Cancer in press.
38. Hilton J.L., Geisler J.P., Rathe J.A., Hattermann-Zogg M.A., DeYoung B., and Buller R.E. Inactivation of BRCA1 and BRCA2 in ovarian cancer. J Natl Cancer Inst 94 18 (2002) 1396-1406
39. Piek J.M., Torrenga B., Hermsen B., Verheijen R.H., Zweemer R.P., Gille J.J., et al. Histopathological characteristics of BRCA1- and BRCA2-associated intraperitoneal cancer: a clinic-based study. Fam Cancer 2 2 (2003) 73-78
40. Leitao Jr. M.M., Boyd J., Hummer A., Olvera N., Arroyo C.D., Venkatraman E., et al. Clinicopathologic analysis of early-stage sporadic ovarian carcinoma. Am J Surg Pathol 28 2 (2004) 147-159
41. Crum C.P., Drapkin R., Kindelberger D., Medeiros F., Miron A., and Lee Y. Lessons from BRCA: the tubal fimbria emerges as an origin for pelvic serous cancer. Clin Med Res 5 1 (2007) 35-44
42. Salvador S, Gilks B, Köbel M, Huntsman D, Rosen B, Miller D. The Fallopian Tube: Primary Site of Most Pelvic High-Grade Serous Carcinomas. Int J Gynaecol Cancer in press.