메뉴 건너뛰기




Volumn 295, Issue 1, 2008, Pages

Muscarinic receptor M1 and phosphodiesterase 1 are key determinants in pulmonary vascular dysfunction following perinatal hypoxia in mice

Author keywords

Acetylcholine; Endothelial nitric oxide synthase; Muscarinic receptors; Phosphodiesterases; Pulmonary artery

Indexed keywords

CALCIMYCIN; CALCIUM; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MESSENGER RNA; MUSCARINIC M1 RECEPTOR; NITRIC OXIDE; PHOSPHODIESTERASE I; VINPOCETINE; ACETYLCHOLINE; VASODILATOR AGENT;

EID: 49049122102     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00264.2007     Document Type: Article
Times cited : (20)

References (76)
  • 1
    • 57049127287 scopus 로고    scopus 로고
    • Abman SH, Kinsella JP, Parker TA, Storme L, Le Cras TD. Physiologic Roles of Nitric Oxide in the Perinatal Pulmonary Circulation, edited by Weir EK, Archer SL, Reeves JT. Armonk, NY: Futura, 2000, p. 239-260.
    • Abman SH, Kinsella JP, Parker TA, Storme L, Le Cras TD. Physiologic Roles of Nitric Oxide in the Perinatal Pulmonary Circulation, edited by Weir EK, Archer SL, Reeves JT. Armonk, NY: Futura, 2000, p. 239-260.
  • 2
    • 0024454868 scopus 로고
    • Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta
    • Ahn HS, Crim W, Romano M, Sybertz E, Pitts B. Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta. Biochem Pharmacol 38: 3331-3339, 1989.
    • (1989) Biochem Pharmacol , vol.38 , pp. 3331-3339
    • Ahn, H.S.1    Crim, W.2    Romano, M.3    Sybertz, E.4    Pitts, B.5
  • 3
    • 0028237728 scopus 로고
    • Pharmacological characterization of muscarinic receptors mediating acetylcholine-induced contraction and relaxation in rabbit intrapulmonary arteries
    • Altiere RJ, Travis DC, Roberts J, Thompson DC. Pharmacological characterization of muscarinic receptors mediating acetylcholine-induced contraction and relaxation in rabbit intrapulmonary arteries. J Pharmacol Exp Ther 270: 269-276, 1994.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 269-276
    • Altiere, R.J.1    Travis, D.C.2    Roberts, J.3    Thompson, D.C.4
  • 4
    • 0034650064 scopus 로고    scopus 로고
    • In utero programming of cardiovascular disease
    • Barker DJ. In utero programming of cardiovascular disease. Theriogenology 53: 555-574, 2000.
    • (2000) Theriogenology , vol.53 , pp. 555-574
    • Barker, D.J.1
  • 5
    • 0029039835 scopus 로고
    • Regulation of pulmonary vascular tone
    • Barnes PJ, Liu SF. Regulation of pulmonary vascular tone. Pharmacol Rev 47: 87-131, 1995.
    • (1995) Pharmacol Rev , vol.47 , pp. 87-131
    • Barnes, P.J.1    Liu, S.F.2
  • 7
    • 0037633870 scopus 로고    scopus 로고
    • Dietary protein restriction in pregnancy induces hypertension and vascular defects in rat male offspring
    • Brawley L, Itoh S, Torrens C, Barker A, Bertram C, Poston L, Hanson M. Dietary protein restriction in pregnancy induces hypertension and vascular defects in rat male offspring. Pediatr Res 54: 83-90, 2003.
    • (2003) Pediatr Res , vol.54 , pp. 83-90
    • Brawley, L.1    Itoh, S.2    Torrens, C.3    Barker, A.4    Bertram, C.5    Poston, L.6    Hanson, M.7
  • 8
    • 0034705534 scopus 로고    scopus 로고
    • The role of the sodium-calcium exchanger for calcium extrusion in coronary arteries
    • Budel S, Beny JL. The role of the sodium-calcium exchanger for calcium extrusion in coronary arteries. Life Sci 67: 549-557, 2000.
    • (2000) Life Sci , vol.67 , pp. 549-557
    • Budel, S.1    Beny, J.L.2
  • 9
    • 0027492948 scopus 로고
    • Loss of endothelium-dependent relaxation in proximal pulmonary arteries from rats exposed to chronic hypoxia: Effects of in vivo and in vitro supplementation with L-arginine
    • Carville C, Raffestin B, Eddahibi S, Blouquit Y, Adnot S. Loss of endothelium-dependent relaxation in proximal pulmonary arteries from rats exposed to chronic hypoxia: effects of in vivo and in vitro supplementation with L-arginine. J Cardiovasc Pharmacol 22: 889-896, 1993.
    • (1993) J Cardiovasc Pharmacol , vol.22 , pp. 889-896
    • Carville, C.1    Raffestin, B.2    Eddahibi, S.3    Blouquit, Y.4    Adnot, S.5
  • 10
    • 0025959706 scopus 로고
    • Influence of hypobaric hypoxia in infancy on the subsequent development of vasoconstrictive pulmonary vascular disease in the Wistar albino rat
    • Caslin A, Heath D, Smith P. Influence of hypobaric hypoxia in infancy on the subsequent development of vasoconstrictive pulmonary vascular disease in the Wistar albino rat. J Pathol 163: 133-141, 1991.
    • (1991) J Pathol , vol.163 , pp. 133-141
    • Caslin, A.1    Heath, D.2    Smith, P.3
  • 11
    • 0027208248 scopus 로고
    • Muscarinic receptors-characterization, coupling and function
    • Caulfield MP. Muscarinic receptors-characterization, coupling and function. Pharmacol Ther 58: 319-379, 1993.
    • (1993) Pharmacol Ther , vol.58 , pp. 319-379
    • Caulfield, M.P.1
  • 13
    • 11144279295 scopus 로고    scopus 로고
    • Regulation of pulmonary venous tone in response to muscarinic receptor activation
    • Ding X, Murray PA. Regulation of pulmonary venous tone in response to muscarinic receptor activation. Am J Physiol Lung Cell Mol Physiol 288: L131-L140, 2005.
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288
    • Ding, X.1    Murray, P.A.2
  • 17
    • 33748421398 scopus 로고    scopus 로고
    • Endothelial dysfunction: A multifaceted disorder (The Wiggers Award Lecture)
    • Feletou M, Vanhoutte PM. Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture). Am J Physiol Heart Circ Physiol 291: H985-H1002, 2006.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Feletou, M.1    Vanhoutte, P.M.2
  • 18
    • 0031969359 scopus 로고    scopus 로고
    • Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs
    • Fike CD, Kaplowitz MR, Thomas CJ, Nelin LD. Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs. Am J Physiol Lung Cell Mol Physiol 274: L517-L526, 1998.
    • (1998) Am J Physiol Lung Cell Mol Physiol , vol.274
    • Fike, C.D.1    Kaplowitz, M.R.2    Thomas, C.J.3    Nelin, L.D.4
  • 20
    • 0036893519 scopus 로고    scopus 로고
    • Pulmonary hypertension in TNF-α-overexpressing mice is associated with decreased VEGF gene expression
    • Fujita M, Mason RJ, Cool C, Shannon JM, Hara N, Fagan KA. Pulmonary hypertension in TNF-α-overexpressing mice is associated with decreased VEGF gene expression. J Appl Physiol 93: 2162-2170, 2002.
    • (2002) J Appl Physiol , vol.93 , pp. 2162-2170
    • Fujita, M.1    Mason, R.J.2    Cool, C.3    Shannon, J.M.4    Hara, N.5    Fagan, K.A.6
  • 22
    • 33847713292 scopus 로고    scopus 로고
    • Role of Rho kinases in PKG-mediated relaxation of pulmonary arteries of fetal lambs exposed to chronic high altitude hypoxia
    • Gao Y, Portugal AD, Negash S, Zhou W, Longo LD, Usha Raj J. Role of Rho kinases in PKG-mediated relaxation of pulmonary arteries of fetal lambs exposed to chronic high altitude hypoxia. Am J Physiol Lung Cell Mol Physiol 292: L678-L684, 2007.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292
    • Gao, Y.1    Portugal, A.D.2    Negash, S.3    Zhou, W.4    Longo, L.D.5    Usha Raj, J.6
  • 23
    • 0031774268 scopus 로고    scopus 로고
    • Heterogeneity in endothelium-derived nitric oxide-mediated relaxation of different sized pulmonary arteries of newborn lambs
    • Gao Y, Tolsa JF, Raj JU. Heterogeneity in endothelium-derived nitric oxide-mediated relaxation of different sized pulmonary arteries of newborn lambs. Pediatr Res 44: 723-729, 1998.
    • (1998) Pediatr Res , vol.44 , pp. 723-729
    • Gao, Y.1    Tolsa, J.F.2    Raj, J.U.3
  • 24
    • 0029055964 scopus 로고
    • Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
    • Giaid A, Saleh D. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N Engl J Med 333: 214-221, 1995.
    • (1995) N Engl J Med , vol.333 , pp. 214-221
    • Giaid, A.1    Saleh, D.2
  • 25
    • 4344632905 scopus 로고    scopus 로고
    • Developmental origins of disease paradigm: A mechanistic and evolutionary perspective
    • Gluckman PD, Hanson MA. Developmental origins of disease paradigm: a mechanistic and evolutionary perspective. Pediatr Res 56: 311-317, 2004.
    • (2004) Pediatr Res , vol.56 , pp. 311-317
    • Gluckman, P.D.1    Hanson, M.A.2
  • 26
    • 4544366928 scopus 로고    scopus 로고
    • Living with the past: Evolution, development, and patterns of disease
    • Gluckman PD, Hanson MA. Living with the past: evolution, development, and patterns of disease. Science 305: 1733-1736, 2004.
    • (2004) Science , vol.305 , pp. 1733-1736
    • Gluckman, P.D.1    Hanson, M.A.2
  • 29
    • 0021337094 scopus 로고
    • Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle
    • Hagiwara M, Endo T, Hidaka H. Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle. Biochem Pharmacol 33: 453-457, 1984.
    • (1984) Biochem Pharmacol , vol.33 , pp. 453-457
    • Hagiwara, M.1    Endo, T.2    Hidaka, H.3
  • 30
    • 0025270344 scopus 로고
    • Pulmonary vascular resistance in adult rats exposed to hypoxia in the neonatal period
    • Hakim TS, Mortola JP. Pulmonary vascular resistance in adult rats exposed to hypoxia in the neonatal period. Can J Physiol Pharmacol 68: 419-424, 1990.
    • (1990) Can J Physiol Pharmacol , vol.68 , pp. 419-424
    • Hakim, T.S.1    Mortola, J.P.2
  • 31
    • 0025063574 scopus 로고
    • Perinatal hypoxia increases hypoxic pulmonary vasoconstriction in adult rats recovering from chronic exposure to hypoxia
    • Hampl V, Herget J. Perinatal hypoxia increases hypoxic pulmonary vasoconstriction in adult rats recovering from chronic exposure to hypoxia. Am Rev Respir Dis 142: 619-624, 1990.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 619-624
    • Hampl, V.1    Herget, J.2
  • 32
    • 0029444554 scopus 로고
    • Perinatal lung injury extends in adults the site of hypoxic pulmonary vasoconstriction upstream
    • Herget J, Kuklik V. Perinatal lung injury extends in adults the site of hypoxic pulmonary vasoconstriction upstream. Physiol Res 44: 25-30, 1995.
    • (1995) Physiol Res , vol.44 , pp. 25-30
    • Herget, J.1    Kuklik, V.2
  • 33
  • 35
    • 0033004648 scopus 로고    scopus 로고
    • Maternal food restriction in the second half of pregnancy affects vascular function but not blood pressure of rat female offspring
    • Holemans K, Gerber R, Meurrens K, De Clerck F, Poston L, Van Assche FA. Maternal food restriction in the second half of pregnancy affects vascular function but not blood pressure of rat female offspring. Br J Nutr 81: 73-79, 1999.
    • (1999) Br J Nutr , vol.81 , pp. 73-79
    • Holemans, K.1    Gerber, R.2    Meurrens, K.3    De Clerck, F.4    Poston, L.5    Van Assche, F.A.6
  • 38
    • 0022461711 scopus 로고
    • Activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor from intrapulmonary artery and vein: Stimulation by acetylcholine, bradykinin and arachidonic acid
    • Ignarro LJ, Harbison RG, Wood KS, Kadowitz PJ. Activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor from intrapulmonary artery and vein: stimulation by acetylcholine, bradykinin and arachidonic acid. J Pharmacol Exp Ther 237: 893-900, 1986.
    • (1986) J Pharmacol Exp Ther , vol.237 , pp. 893-900
    • Ignarro, L.J.1    Harbison, R.G.2    Wood, K.S.3    Kadowitz, P.J.4
  • 39
    • 33749440087 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptors
    • Ishii M, Kurachi Y. Muscarinic acetylcholine receptors. Curr Pharm Des 12: 3573-3581, 2006.
    • (2006) Curr Pharm Des , vol.12 , pp. 3573-3581
    • Ishii, M.1    Kurachi, Y.2
  • 40
    • 0036084399 scopus 로고    scopus 로고
    • Chronic hypoxia attenuates cGMP-dependent pulmonary vasodilation
    • Jernigan NL, Resta TC. Chronic hypoxia attenuates cGMP-dependent pulmonary vasodilation. Am J Physiol Lung Cell Mol Physiol 282: L1366-L1375, 2002.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.282
    • Jernigan, N.L.1    Resta, T.C.2
  • 42
    • 0024805433 scopus 로고
    • Endothelium-dependent relaxation and cyclic GMP accumulation in rabbit pulmonary artery are selectively impaired by moderate hypoxia
    • Johns RA, Linden JM, Peach MJ. Endothelium-dependent relaxation and cyclic GMP accumulation in rabbit pulmonary artery are selectively impaired by moderate hypoxia. Circ Res 65: 1508-1515, 1989.
    • (1989) Circ Res , vol.65 , pp. 1508-1515
    • Johns, R.A.1    Linden, J.M.2    Peach, M.J.3
  • 43
    • 1542375797 scopus 로고    scopus 로고
    • Effects of perinatal exposure to hypoxia upon the pulmonary circulation of the adult rat
    • Jones RD, Morice AH, Emery CJ. Effects of perinatal exposure to hypoxia upon the pulmonary circulation of the adult rat. Physiol Res 53: 11-17, 2004.
    • (2004) Physiol Res , vol.53 , pp. 11-17
    • Jones, R.D.1    Morice, A.H.2    Emery, C.J.3
  • 44
    • 38049132717 scopus 로고    scopus 로고
    • Sildenafil in hypoxic pulmonary hypertension potentiates a compensatory up-regulation of NO-cGMP signaling
    • Kirsch M, Kemp-Harper B, Weissmann N, Grimminger F, Schmidt HH. Sildenafil in hypoxic pulmonary hypertension potentiates a compensatory up-regulation of NO-cGMP signaling. FASEB J 22: 30-40, 2008.
    • (2008) FASEB J , vol.22 , pp. 30-40
    • Kirsch, M.1    Kemp-Harper, B.2    Weissmann, N.3    Grimminger, F.4    Schmidt, H.H.5
  • 45
    • 33847410021 scopus 로고    scopus 로고
    • The nitric oxide/cGMP signaling pathway in pulmonary hypertension
    • Klinger JR. The nitric oxide/cGMP signaling pathway in pulmonary hypertension. Clin Chest Med 28: 143-167, 2007.
    • (2007) Clin Chest Med , vol.28 , pp. 143-167
    • Klinger, J.R.1
  • 46
    • 0033970502 scopus 로고    scopus 로고
    • Maturational changes in endothelium-derived nitric oxide-mediated relaxation of ovine pulmonary arteries
    • Kolber KA, Gao Y, Raj JU. Maturational changes in endothelium-derived nitric oxide-mediated relaxation of ovine pulmonary arteries. Biol Neonate 77: 123-130, 2000.
    • (2000) Biol Neonate , vol.77 , pp. 123-130
    • Kolber, K.A.1    Gao, Y.2    Raj, J.U.3
  • 48
    • 0030023029 scopus 로고    scopus 로고
    • Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung
    • Le Cras TD, Xue C, Rengasamy A, Johns RA. Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung. Am J Physiol Lung Cell Mol Physiol 270: L164-L170, 1996.
    • (1996) Am J Physiol Lung Cell Mol Physiol , vol.270
    • Le Cras, T.D.1    Xue, C.2    Rengasamy, A.3    Johns, R.A.4
  • 49
    • 0034880704 scopus 로고    scopus 로고
    • Upregulation of lung soluble guanylate cyclase during chronic hypoxia is prevented by deletion of eNOS
    • Li D, Laubach VE, Johns RA. Upregulation of lung soluble guanylate cyclase during chronic hypoxia is prevented by deletion of eNOS. Am J Physiol Lung Cell Mol Physiol 281: L369-L376, 2001.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.281
    • Li, D.1    Laubach, V.E.2    Johns, R.A.3
  • 50
    • 0032754248 scopus 로고    scopus 로고
    • Soluble guanylate cyclase gene expression and localization in rat lung after exposure to hypoxia
    • Li D, Zhou N, Johns RA. Soluble guanylate cyclase gene expression and localization in rat lung after exposure to hypoxia. Am J Physiol Lung Cell Mol Physiol 277: L841-L847, 1999.
    • (1999) Am J Physiol Lung Cell Mol Physiol , vol.277
    • Li, D.1    Zhou, N.2    Johns, R.A.3
  • 52
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 329: 2002-2012, 1993.
    • (1993) N Engl J Med , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 53
    • 0025194259 scopus 로고
    • 5-[imino(nitroamino)methyl]-L-ornithine) impairs endothelium-dependent dilations by inhibiting cytosolic nitric oxide synthesis from L-arginine
    • 5-[imino(nitroamino)methyl]-L-ornithine) impairs endothelium-dependent dilations by inhibiting cytosolic nitric oxide synthesis from L-arginine. Naunyn Schmiedebergs Arch Pharmacol 341: 143-147, 1990.
    • (1990) Naunyn Schmiedebergs Arch Pharmacol , vol.341 , pp. 143-147
    • Mulsch, A.1    Busse, R.2
  • 54
    • 0347367306 scopus 로고    scopus 로고
    • Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension
    • Murata T, Sato K, Hori M, Ozaki H, Karaki H. Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension. J Biol Chem 277: 44085-44092, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 44085-44092
    • Murata, T.1    Sato, K.2    Hori, M.3    Ozaki, H.4    Karaki, H.5
  • 55
    • 33846200014 scopus 로고    scopus 로고
    • Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: Role for PDE1
    • Murray F, Patel HH, Suda RY, Zhang S, Thistlethwaite PA, Yuan JX, Insel PA. Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1. Am J Physiol Lung Cell Mol Physiol 292: L294-L303, 2007.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292
    • Murray, F.1    Patel, H.H.2    Suda, R.Y.3    Zhang, S.4    Thistlethwaite, P.A.5    Yuan, J.X.6    Insel, P.A.7
  • 56
    • 35348919542 scopus 로고    scopus 로고
    • Regulation of cGMP-dependent protein kinase-mediated vasodilation by hypoxia-induced reactive species in ovine fetal pulmonary veins
    • Negash S, Gao Y, Zhou W, Liu J, Chinta S, Raj JU. Regulation of cGMP-dependent protein kinase-mediated vasodilation by hypoxia-induced reactive species in ovine fetal pulmonary veins. Am J Physiol Lung Cell Mol Physiol 293: L1012-L1020, 2007.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293
    • Negash, S.1    Gao, Y.2    Zhou, W.3    Liu, J.4    Chinta, S.5    Raj, J.U.6
  • 61
    • 0037385846 scopus 로고    scopus 로고
    • Chronic moderate hypoxia and protein malnutrition both induce growth retardation, but have distinct effects on arterial endothelium-dependent reactivity in the chicken embryo
    • Ruijtenbeek K, Kessels LC, De Mey JG, Blanco CE. Chronic moderate hypoxia and protein malnutrition both induce growth retardation, but have distinct effects on arterial endothelium-dependent reactivity in the chicken embryo. Pediatr Res 53: 573-579, 2003.
    • (2003) Pediatr Res , vol.53 , pp. 573-579
    • Ruijtenbeek, K.1    Kessels, L.C.2    De Mey, J.G.3    Blanco, C.E.4
  • 62
    • 0042859823 scopus 로고    scopus 로고
    • Cyclic GMP phosphodiesterases and regulation of smooth muscle function
    • Rybalkin SD, Yan C, Bornfeldt KE, Beavo JA. Cyclic GMP phosphodiesterases and regulation of smooth muscle function. Circ Res 93: 280-291, 2003.
    • (2003) Circ Res , vol.93 , pp. 280-291
    • Rybalkin, S.D.1    Yan, C.2    Bornfeldt, K.E.3    Beavo, J.A.4
  • 63
    • 0033606527 scopus 로고    scopus 로고
    • Augmented vasoreactivity in adult life associated with perinatal vascular insult
    • Sartori C, Allemann Y, Trueb L, Delabays A, Nicod P, Scherrer U. Augmented vasoreactivity in adult life associated with perinatal vascular insult. Lancet 353: 2205-2207, 1999.
    • (1999) Lancet , vol.353 , pp. 2205-2207
    • Sartori, C.1    Allemann, Y.2    Trueb, L.3    Delabays, A.4    Nicod, P.5    Scherrer, U.6
  • 66
    • 0038637480 scopus 로고    scopus 로고
    • Changes in functional and histological distributions of nitric oxide synthase caused by chronic hypoxia in rat small pulmonary arteries
    • Shirai M, Pearson JT, Shimouchi A, Nagaya N, Tsuchimochi H, Ninomiya I, Mori H. Changes in functional and histological distributions of nitric oxide synthase caused by chronic hypoxia in rat small pulmonary arteries. Br J Pharmacol 139: 899-910, 2003.
    • (2003) Br J Pharmacol , vol.139 , pp. 899-910
    • Shirai, M.1    Pearson, J.T.2    Shimouchi, A.3    Nagaya, N.4    Tsuchimochi, H.5    Ninomiya, I.6    Mori, H.7
  • 68
    • 0034011190 scopus 로고    scopus 로고
    • Brief perinatal hypoxia increases severity of pulmonary hypertension after reexposure to hypoxia in infant rats
    • Tang JR, Le Cras TD, Morris KG Jr, Abman SH. Brief perinatal hypoxia increases severity of pulmonary hypertension after reexposure to hypoxia in infant rats. Am J Physiol Lung Cell Mol Physiol 278: L356-L364, 2000.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.278
    • Tang, J.R.1    Le Cras, T.D.2    Morris Jr, K.G.3    Abman, S.H.4
  • 70
    • 33748129483 scopus 로고    scopus 로고
    • Role of membrane potential in endothelium-dependent relaxation of isolated mouse main pulmonary artery
    • Tolsa JF, Marino M, Peyter AC, Beny JL. Role of membrane potential in endothelium-dependent relaxation of isolated mouse main pulmonary artery. J Cardiovasc Pharmacol 47: 501-507, 2006.
    • (2006) J Cardiovasc Pharmacol , vol.47 , pp. 501-507
    • Tolsa, J.F.1    Marino, M.2    Peyter, A.C.3    Beny, J.L.4
  • 75
    • 19444385248 scopus 로고    scopus 로고
    • Effects of maternal hypoxia or nutrient restriction during pregnancy on endothelial function in adult male rat offspring
    • Williams SJ, Hemmings DG, Mitchell JM, McMillen IC, Davidge ST. Effects of maternal hypoxia or nutrient restriction during pregnancy on endothelial function in adult male rat offspring. J Physiol 565: 125-135, 2005.
    • (2005) J Physiol , vol.565 , pp. 125-135
    • Williams, S.J.1    Hemmings, D.G.2    Mitchell, J.M.3    McMillen, I.C.4    Davidge, S.T.5
  • 76
    • 3242852051 scopus 로고
    • Interaction of hydrolysis-resistant analogs of cyclic GMP with the phosphodiesterase and light-sensitive channel of retinal rod outer segments
    • Zimmerman AL, Yamanaka G, Eckstein F, Baylor DA, Stryer L. Interaction of hydrolysis-resistant analogs of cyclic GMP with the phosphodiesterase and light-sensitive channel of retinal rod outer segments. Proc Natl Acad Sci USA 82: 8813-8817, 1985.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 8813-8817
    • Zimmerman, A.L.1    Yamanaka, G.2    Eckstein, F.3    Baylor, D.A.4    Stryer, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.