Do the benefits of daily inhaled steroid treatment of mild asthma outweigh the risks?

Archives of Disease in Childhood

Volumn 93, Issue 8, 2008, Pages 644-645

  Pedersen, Søren ^a  

^a KOLDING HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; PREDNISOLONE; STEROID; ANTIASTHMATIC AGENT;

ASTHMA; DISEASE SEVERITY; DRUG EFFICACY; GROWTH DISORDER; HUMAN; PRIORITY JOURNAL; RISK BENEFIT ANALYSIS; SHORT SURVEY; STEROID THERAPY; TREATMENT OUTCOME; CHILD; DOSE RESPONSE; DRUG EFFECT; GROWTH; INHALATIONAL DRUG ADMINISTRATION; NOTE; PHYSIOLOGY; PRESCHOOL CHILD; RISK FACTOR;

ADMINISTRATION, INHALATION; ADRENAL CORTEX HORMONES; ANTI-ASTHMATIC AGENTS; ASTHMA; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; GROWTH; HUMANS; PREDNISOLONE; RISK FACTORS; TREATMENT OUTCOME;

EID: 49049115766     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/adc.2007.135145     Document Type: Short Survey

References (16)

1. Turpeinen M, Nikander K, Pelkonen AS, et al. Daily versus as-needed inhaled corticosteroid for mild persistent asthma (The Helsinki early intervention childhood asthma study). Arch Dis Child 2008;93:654- 9.
2. The Childhood Asthma Management Program Research Group. Long-term effects of budesonide or nedocromil in children with asthma. New Engl J Med 2000;243:1054-1063.
3. Chen YZ, Busse WW, Pedersen S, et al. Early intervention of recent onset mild persistent asthma in children aged under 11 yrs: the steroid treatment as regular therapy in early asthma (START) trial. Pediatr Allergy Immunol 2006;17:7-13.
4. Pauwels RA, Pedersen S, Busse WW, et al. Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial. Lancet 2003;361:1071-1076.
5. Ostrom NK, Decotiis BA, Lincourt WR, et al. Comparative efficacy and safety of low-dose fluticasone propionate and montelukast in children with persistent asthma. J Pediatr 2005;147:213-220.
6. Garcia Garcia ML, Wahn U, Gilles L, et al. Montelukast, compared with fluticasone, for control of asthma among 6- to 14-year-old patients with mild asthma: the MOSAIC study. Pediatrics 2005;116:360-369.
7. Zeiger RS, Bird SR, Kaplan MS, et al. Short-term and long-term asthma control in patients with mild persistent asthma receiving montelukast or fluticasone: a randomized controlled trial. Am J Med 2005;118:649-57.
8. Pedersen S. Do inhaled corticosteroids inhibit growth in children? Am J Respir Crit Care Med 2001;164:521-35.
9. Pedersen S. Clinical safety of inhaled corticosteroids for asthma in children: an update of long-term trials. Drug Saf 2006;29:599- 612.
10. Shabu A, Flanagan O, Dineen B, et al. Prevalence of asthma in Galway school children. Ir Med J 2004;100:491-3.
11. Robertson C, Rubinfeld A, Bowes G. Deaths from asthma in Victoria: a 12-month survey. Med J Aust 1990;152:511-7.
12. Becker JM, Rogers J, Rossini G, et al. Asthma deaths during sports: report of a 7-year experience. J Allergy Clin Immunol 2004;113:264-7.
13. Weiss K, Buxton M, Andersson FL, et al. Cost-effectiveness of early intervention with once-daily budesonide in children with mild persistent asthma: results from the START study. Pediatr Allergy Immunol 2006;17:21-7.
14. Carranza R, Edwards L, Lincourt W, et al. The relationship between health-related quality of life, lung function and daily symptoms in patients with persistent asthma. Respir Med 2004;98:1157-65.
15. O'Byrne PM, Pedersen S. Measuring efficacy and safety of different inhaled corticosteroid preparations. J Allergy Clin Immunol 1998;102:879-86.
16. Gustafsson PM, Watson L, Davis KJ, et al. Poor asthma control in children: evidence from epidemiological surveys and implications for clinical practice. Int J Clin Pract 2006;60:321-34.