Development of a gastrointestinal tract microscale cell culture analog to predict drug transport

MCB Molecular and Cellular Biomechanics

Volumn 5, Issue 2, 2008, Pages 119-132

  McAuliffe, Gretchen J ^a   Chang, Jung Yun ^b   Glahn, Raymond P ^c   Shuler, Michael L ^a  

^a Cornell University   (United States)

^b Korea Food and Drug Administration   (South Korea)

^c U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL MEMBRANES; CELLS; CYTOLOGY; MODELS; PHYSIOLOGICAL MODELS; PROJECT MANAGEMENT;

DRUG TRANSPORTS; GASTROINTESTINAL TRACTS; GI TRACTS; IN VITRO; IN-VIVO; INTESTINAL EPITHELIAL CELLS; MICROPOROUS MEMBRANES; PHARMACOKINETIC MODELS; PHYSIOLOGICALLY; TOXIC EFFECTS;

CELL CULTURE;

ANALGESIC AGENT; CYTOCHROME P450 1A2; CYTOCHROME P450 2E1; PARACETAMOL;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL LINE; CULTURE TECHNIQUE; CYTOLOGY; EVALUATION; GASTROINTESTINAL TRACT; HUMAN; INSTRUMENTATION; INTESTINE ABSORPTION; METABOLISM; METHODOLOGY; MICROFLUIDIC ANALYSIS; RAT; TRANSPORT AT THE CELLULAR LEVEL;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; BIOLOGICAL TRANSPORT; CELL CULTURE TECHNIQUES; CELL LINE; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2E1; GASTROINTESTINAL TRACT; HUMANS; INTESTINAL ABSORPTION; MICROFLUIDIC ANALYTICAL TECHNIQUES; MODELS, BIOLOGICAL; RATS;

EID: 49049114566     PISSN: 15565297     EISSN: 15565300     Source Type: Journal    
DOI: None     Document Type: Article

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