Trypanocidal activity of coumarins and styryl-2-pyrones from Polygala sabulosa A.W. Bennett (Polygalaceae)

Revista Brasileira de Farmacognosia

Volumn 18, Issue 2, 2008, Pages 177-182

  Pizzolatti, Moacir G ^a   Mendes, Beatriz G ^a   Cunha Jr , Anildo ^a   Soldi, Cristian ^a   Koga, Adolfo H ^a   Eger, Iriane ^b   Grisard, Edmundo C ^a   Steindel, Mário ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b UNIVERSIDADE DO VALE DO ITAJAÍ   (Brazil)

Author keywords

6 methoxy 7 prenyloxycoumarin; Polygala sabulosa; Styryl 2 pyrones; Trypanocidal activity; Trypanosoma cruzi

Indexed keywords

EID: 49049101899     PISSN: 0102695X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0102-695X2008000200006     Document Type: Article

References (28)

1. 13NMR of flavonoids. New York: Elsevier science.
2. Barbosa-Filho JM, Nascimento-Junior FA, Tomaz ACA, Athayde-Filho PF, Silva MS, Cunha EVL, Souza MFV, Batista LM, Diniz MFFM 2007. Natural products with antileprotic activity. Rev Bras Farmacogn 17: 141-148.
3. Berger I, Barrientos AC, Cáceres A, Hernández M, Rastrelli L, Passreiter CM, Kubelka W 1998. Plants used in Guatemala for treatment of protozoal infections II. Activity of extracts and fractions of five Guatemalan plants against Trypanosoma cruzi. J Ethnopharmacol 62: 107-115.
4. Bezerra JL, Costa GC, Lopes TC, Carvalho ICDS, Patricio FJ, Sousa SM, Amaral FMM, Rebelo JMM, Guerra RNM, Ribeiro MNS, Nascimento FRF 2006. Avaliação da atividade leishmanicida in vitro de plantas medicinais. Rev Bras Farmacogn 16(Supl): 631-637.
5. Chiari E, Duarte DS, Raslan DS, Saude DA, Perry KSP, Boaventura MAD, Grandi TSM, Stehmann JR, Anjos AMG, Oliveira AB 1996. In vitro screening of Asteraceae plant species against Trypanosoma cruzi. Phytother Res 10: 636-638.
6. Cragg GM, Newman DJ, Snader KM 1997. Natural products in drug discovery and development. J Nat Prod 60: 52-60.
7. Croft SL, Urbina JA, Brun R 1997. Chemotherapy of human Leishmaniasis and Trypanosomiasis. In: Hide G, Mottram, JC, Coombs GH, Holmes PH (org). Trypanosomiasis and Leishmaniasis Biology and Control. Wallingford: CAB International, p. 245-257.
8. 13C NMR. Phytochemistry 20: 761-764.
9. Koga AH 2003. Avaliação da atividade tripanocida de compostas obtidos de plantas. Florianópolis, 72p. Dissertaçã o de Mestrado - Programa de Pós-Graduação em Biotecnologia, Universidade Federal de Santa Catarina.
10. Mafezoli J, Vieira PC, Fernandes JB, Silva MFGF, Albuquerque S 2000. In vitro activity of Rutaceae species against the trypomastigote form of Trypanosoma cruzi. J Ethnopharmacol 73: 335-340.
11. Muelas-Serrano S, Nogal JJ, Martinez-Díaz RA, Escario JA, Martínez-Fernandes AR, Gómez-Barrio A 2000. In vitro screening of American plant extracts on Trypanosoma cruzi and Trichomonas vaginalis. J Ethnopharmacol 71: 101-107.
12. Pizzolatti MG, Luciano C, Delle Monache F 2000. Styryl- and dihydrostyryl-2-pyrone derivatives from Polygala sabulosa. Phytochemistry 55: 819-822.
13. Pizzolatti MG, Koga AH, Grisard EC, Steindel M 2003. Trypanocidal activity of extracts from Brazilian Atlantic Rain Forest plant species. Phytomedicine 10: 422-426.
14. Pizzolatti MG, Cunha Jr A, Pereira WS, Delle Monache F 2004. A new styryl-pyrone derivative from Polygala sabuolosa (Polygalaceae). Biochem Syst Ecol 32: 603-606.
15. Ramirez LE, Lages-Silva E, Pianetti GM, Rabelo RM, Bordin JO, Moraes-Souza H 1995. Prevention of transfusion-associated Chagas disease by sterilization of Trypanosoma cruzi-infected blood with gentian violet, ascorbic acid and light. Transfusion 35: 226-230.
16. Saúde-Guimarães DA, Faria AR 2007. Substâncias da natureza com atividade anti-Trypanosoma cruzi. Rev Bras Farmacogn 17: 455-465.
17. Schinella GR, Tournier HA, Prieto JM, Ríos JL, Buschiazzo H, Zaidenberg A 2002. Inhibition of Trypanosoma cruzi growth by medical plant extracts. Fitoterapia 73: 569-575.
18. Schmuñis GA, Zicker F, Cruz JR, Cuchi P 2001. Safety of blood supply for infectious diseases in Latin American countries, 1994-1997. Am J Trop Med Hyg 65: 924-930.
19. Scio E, Ribeiro A, Alves TMA, Romanha AJ, Souza Filho JD, Cordell GA, Zani CL 2003a. Diterpenes from Alomia myriadenia (Asteraceae) with cytotoxic and trypanocidal activity. Phytochemistry 64: 1125-1131.
20. Scio E, Ribeiro A, Alves TMA, Romanha AJ, Shin YG, Cordell GA, Zani CL 2003b. New bioactive coumarins from Kielmeyera albopunctata. J Nat Prod 66: 634-637.
21. Sepulveda-Boza S, Cassels BK 1996. Plant metabolites active against Trypanosoma cruzi. Planta Med 62: 98-105.
22. 50 values and cell survival. Eur J Clin Chem Clin Biochem 33: 813-823.
23. Silveira D, Wagner H, Chiari E, Lombardi JA, Assunção AC, Oliveira AB, Raslan DS 2005. Biological activity of the aqueous extract of Lychnophora pinaster Mart. Braz J Pharmacogn 15: 294-297.
24. Soejarto DD 1996. Biodiversity prospecting and benefit sharing: perspectives from the field. J Ethnopharmacol 51: 1-15.
25. Tasdemir D, Kaiser M, Brun R, Yardley V, Schmidt TJ, Tosun F, Ruëdi P 2006. Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies. Antimicrob. Agents Chemother. 50: 1352-1364.
26. Weniger B, Robledo S, Arango GJ, Deharo E, Aragón R, Muñoz V, Callapa J, Lobstein A, Anton R 2001. Antiprotozoal activities of Colombian plants. J Ethnopharmacol 78: 193-200.
27. WHO 2002. World Health Organization. Chagas disease. Strategic Direction for Research, TDR. Training in Tropical Disease. Geneva: World Health Organization.
28. Zani CL, Chaves PPG, Queiroz RO, Mendes NM, Oliveira AB, Cardoso JE, Anjos AMG, Grandi TSM 1995. Brine shrimp lethality assay as a prescreening system for anti-Trypanosoma cruzi activity. Phytomedicine 2: 47-50.