Gliotoxin enhances radiotherapy via inhibition of radiation-induced GADD45a, p38, and NFκB activation

Journal of Cellular Biochemistry

Volumn 104, Issue 6, 2008, Pages 2174-2184

  Hur, Jung Mu ^a   Yun, Hye Jeong ^a   Yang, Soo Hyung ^a   Lee, Woo Yiel ^b   Joe, Min Ho ^a   Kim, Dongho ^a  

^a Korea Atomic Energy Research Institute   (South Korea)

^b Konyang University   (South Korea)

Author keywords

Apoptosis; Gadd45a; Gliotoxin; p38; Radiotherapy

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CASPASE 3; COBALT 60; GLIOTOXIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROTEIN BAX; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GAMMA IRRADIATION; HEPATOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RADIATION DOSE; RADIOSENSITIVITY; WESTERN BLOTTING;

APOPTOSIS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; ENZYME ACTIVATION; GAMMA RAYS; GLIOTOXIN; HUMANS; MODELS, BIOLOGICAL; NF-KAPPA B; NITRIC OXIDE; NUCLEAR PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RADIATION TOLERANCE; REACTIVE OXYGEN SPECIES;

EID: 49049098265     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21776     Document Type: Article

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