Telomeres and race: What can we learn about human biology from health differentials?

Aging Cell

Volumn 7, Issue 4, 2008, Pages 448-450

  Kaufman, Jay S ^a   Cooper, Richard S ^b,c  

^a IL   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c UNIVERSITY OF THE WEST INDIES   (Jamaica)

Author keywords

Epidemiology; Mortality risk; Telomeres

Indexed keywords

RESTRICTION ENDONUCLEASE;

AGING; BODY HEIGHT; BODY MASS; CARDIOVASCULAR DISEASE; CAUCASIAN; DEMOGRAPHY; FAMILY STUDY; GENETIC EPIDEMIOLOGY; HEART DISEASE; HEREDITY; HERITABILITY; HUMAN; LEUKOCYTE; LIFESPAN; MOLECULAR BIOLOGY; NEGRO; POLYMERASE CHAIN REACTION; POPULATION GENETICS; POPULATION RESEARCH; PREDICTION; PRIORITY JOURNAL; RACE DIFFERENCE; REVIEW; SEX DIFFERENCE; SOCIAL ASPECT; TELOMERE; UNITED STATES;

BIOLOGY; CONTINENTAL POPULATION GROUPS; HEALTH; HUMANS; TELOMERE;

EID: 48949118563     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2008.00396.x     Document Type: Review

References (18)

1. Adragna N, Canessa M, Solomon H, Slater E, Tosteson DC (1982) Red cell lithium-sodium countertransport and sodium-potassium cotransport in patients with essential hypertension. Hypertension 4, 795-804.
2. Byrd WM, Clayton LA (2000) An American Health Dilemma. New York: Routledge.
3. Cooper RS, Borke JL (1993) Intracellular ions and hypertension in blacks. In Pathophysiology of Hypertension in Blacks (Fray JCS, Douglas J, eds). Oxford, UK: Oxford University Press, pp. 181-213.
4. Cooper RS, Kaufman JS (1998) Race and hypertension: Science or nescience? Hypertension 32, 813-816.
5. Kaufman JS, Cooper RS (2008) Race in epidemiology: New tools, old problems. Ann Epidemiol 18, 119-123.
6. Demerath EW, Cameron N, Gillman MW, Towne B, Shervogel RM (2004) Telomeres and telomerase in the fetal origins of cardiovascular disease: a review. Human Biol. 76, 127-146.
7. Feldman MW, Lewontin RC (1975) The heritability hang-up. Science 190, 1163-1168.
8. Greenland S, Morgenstern H (2001) Confounding in health research. Annu. Rev. Public Health 22, 189-212.
9. Hunt SC, Chen W, Gardner JP, Kimura M, Srinvasan SR, Eckfeldt JH, Berenson GS, Aviv A (2008) Leukocyte telomeres are longer in African Americans than whites. The NHLBI Family Heart Study and the Bogalusa Heart Study. Aging Cell 7, doi: 10.1111/j.1474-9726.2008.00397.x.
10. Ioannidis JPA, Ntzani EE, Trikalinos TA, Contopoulos-Ioannidis DG (2001) Replication validity of genetic association studies. Nat. Genet. 29, 306-309.
11. Johnson NE (2000) The racial crossover in comorbidity, disability, and mortality. Demography 37, 267-283.
12. Kaplan GA (1999) What is the role of the social environment in understanding inequalities in health? Ann. N.Y Acad. Sci. 896, 116-119.
13. Kaufman JS (2008) Epidemiologic analysis of racial/ethnic disparities: some fundamental issues and a cautionary example. Soc. Sci. Med. 66(8), 1659-1669.
14. Kaufman JS, Cooper RS, McGee D (1997) Socioeconomic status and health in blacks and whites: The problem of residual confounding and the resiliency of race. Epidemiology 6, 621-628.
15. Kimura M, Hjelmborg JVB, Gardner JP, Bathum L, Brimacombe M, Lu X, Christiansen L, Vaupel JW, Aviv A, Christensen K (2008) Short telomeres forecast mortality: Study of leukocytes in elderly Danish twins. Am. J. Epidemiol 167, 799-806.
16. Kington RS, Nickens HW (2001) Racial and ethnic differences in health: recent trends, current patterns, future directions. In America Becoming: Racial Trends and Their Consequences, Vol. II. Commission on Behavioral and Social Sciences and Education, National Research Council (Smelser NJ, Wilson WJ., Mitchell F, eds). Washington, DC: National Academy Press, pp. 253-310.
17. Myrdal G (1962) An American Dilemma: The Negro Problem and Modern Democracy. New York: Harper & Row.
18. Serre D, Montpetit A, ParéG, Engert JC, Yusuf S, Keavney B, Hudson TJ, Anand S (2008) Correction of population stratification in large multi-ethnic association studies. PLo S ONE 3, e1382.