Use of short tandem repeat sequences to study Mycobacterium leprae in leprosy patients in Malawi and India

PLoS Neglected Tropical Diseases

Volumn 2, Issue 4, 2008, Pages

  Young, Saroj K ^a   Ponnighaus, Jorg M ^b   Jain, Suman ^c   Lucas, Sebastian ^d   Suneetha, Sujai ^c   Lockwood, Diana N J ^a   Young, Douglas B ^e   Fine, Paul E M ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b KARONGA PREVENTION STUDY   (Malawi)

^c LEPRA Society   (India)

^d ST THOMAS HOSPITAL   (United Kingdom)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENETICS; BACTERIAL TRANSMISSION; BACTERIUM ISOLATE; CLINICAL ARTICLE; CONTROLLED STUDY; EPIDEMIOLOGICAL DATA; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN TISSUE; INDIA; LEPROSY; MALAWI; MYCOBACTERIUM LEPRAE; NERVE BIOPSY; NONHUMAN; REINFECTION; RELAPSE; SHORT TANDEM REPEAT; SKIN BIOPSY; ADULT; CLASSIFICATION; GENETIC POLYMORPHISM; GENETICS; MICROBIOLOGY; MIDDLE AGED; MOLECULAR EVOLUTION; PATHOLOGY; SKIN;

MICROSATELLITE DNA;

ADULT; EVOLUTION, MOLECULAR; GENETIC VARIATION; GENOTYPE; HUMANS; INDIA; LEPROSY; MALAWI; MICROSATELLITE REPEATS; MIDDLE AGED; MYCOBACTERIUM LEPRAE; POLYMORPHISM, GENETIC; SKIN;

EID: 48949118040     PISSN: None     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pntd.0000214     Document Type: Article

References (18)

1. Meima A, Richardus JH, Habbema JD (2004) Trends in leprosy case detection worldwide since 1985. Lepr Rev 75: 19-33.
2. Fine PE (2007) Leprosy: what is being "eliminated"? Bull World Health Organ 85: 2.
3. Cole ST, Eiglmeier K, Parkhill J, James KD, Thomson NR, et al. (2001) Massive gene decay in the leprosy bacillus. Nature 409: 1007-1011.
4. Monot M, Honore N, Garnier T, Araoz R, Coppee JY, et al. (2005) On the origin of leprosy. Science 308: 1040--1042.
5. Young SK, Taylor GM, Jain S, Suneetha LM, Suneetha S, et al. (2004) Microsatellite mapping of Mycobacterium leprae populations in infected humans. J Clin Microbiol 42: 4931-4936.
6. Groathouse NA, Rivoire B, Kim H, Lee H, Cho SN, et al. (2004) Multiple polymorphic loci for molecular typing of strains of Mycobacterium leprae. J Clin Microbiol 42: 1666-1672.
7. Shin YC, Lee H, Lee H, Walsh GP, Kim JD, et al. (2000) Variable numbers of TTC repeats in Mycobacterium leprae DNA from leprosy patients and use in strain differentiation. J Clin Microbiol 38: 4535-4538.
8. Matsuoka M, Zhang L, Budiawan T, Saeki K, Izumi S (2004) Genotyping of Mycobacterium leprae on the basis of the polymorphism of TTC repeats for analysis of leprosy transmission. J Clin Microbiol 42: 741-745.
9. Lavania M, Katoch VM, Singh HB, Das R, Sharma VD, et al. (2005) Genetic polymorphism among Mycobacterium leprae strains from northern India, by using TTC repeats. Indian J Leper 77: 60-65.
10. Weng X, Wang Z, Liu J, Kimura M, Black WCt, et al. (2007) Identification and distribution of Mycobacterium leprae genotypes in a region of high leprosy prevalence in China: a 3-year molecular epidemiological study. J Clin Microbiol 45: 1728-1734.
11. Zhang L, Budiawan T, Matsuoka M (2005) Diversity of potential short tandem repeats in Mycobacterium leprae and application for molecular typing. J Clin Microbiol 43: 5221-5229.
12. Truman R, Fontes AB, De Miranda AB, Suffys P, Gillis T (2004) Genotypic variation and stability of four variable-number tandem repeats and their suitability for discriminating strains of Mycobacterium leprae. J Clin Microbiol 42: 2558-2565.
13. Ponnighaus JM, Fine PE, Maine N, Bliss L, Kalambo M, et al. (1988) The Lepra Evaluation Project (LEP), an epidemiological study of leprosy in northern Malawi. II: Prevalence rates. Lepr Rev 59. 97-112.
14. Ponnighaus JM, Fine PE, Sterne JA, Bliss L, Wilson RJ, et al. (1994) Incidence rates of leprosy in Karonga District, northern Malawi: patterns by age, sex, BCG status and classification. Int J Lepr Other Mycobact Dis 62: 10-23.
15. Karonga Prevention Trial Group (1996) Randomised controlled trial of single BCG, repeated BCG, or combined BCG and killed Mycobacterium leprae vaccine for prevention of leprosy and tuberculosis in Malawi. Lancet 348: 17-24.
16. Ridley DS, Jopling WH (1966) Classification of leprosy according to immunity. A five-group system. Int J Lepr Other Mycobact Dis 34: 255-273.
17. Bouwman AS, Brown TA (2002) Comparison between silica-based methods for the extraction of DNA from human bones from 18th to min 19th century London. Ancient Biomolecules 4: 173-178.
18. Cole ST, Supply P, Honore N (2001) Repetitive sequences in Mycobacterium leprae and their impact on genome plasticity. Lepr Rev 72: 449-461.