MDCT angiography of the pulmonary arteries: Intravascular contrast enhancement does not depend on iodine concentration when injecting equal amounts of iodine at standardized iodine delivery rates

European Radiology

Volumn 18, Issue 8, 2008, Pages 1690-1695

  Keil, S ^a   Plumhans, C ^a   Behrendt, F F ^a   Das, M ^a   Stanzel, S ^a   Muhlenbruch G ^a   Seidensticker, P ^b   Knackstedt, C ^a   Mahnken, A H ^a   Gunther R W ^a   Wildberger, J E ^a,c  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b BAYER PHARMA AG   (Germany)

^c Helios Klinikum   (Germany)

Author keywords

Contrast material concentration; Pulmonary embolism; Pulmonary multi detector row CT angiography

Indexed keywords

IODINE; IOPROMIDE;

ADULT; ARTICLE; ASCENDING AORTA; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; CONCENTRATION RESPONSE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DESCENDING AORTA; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; DRUG TRANSPORT; FEMALE; FLOW RATE; HUMAN; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MULTIDETECTOR COMPUTED TOMOGRAPHIC ANGIOGRAPHY; PRIORITY JOURNAL; PULMONARY ARTERY;

ANGIOGRAPHY; CONTRAST MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INJECTIONS, INTRA-ARTERIAL; IOHEXOL; MALE; MIDDLE AGED; PULMONARY ARTERY; PULMONARY EMBOLISM; RADIOGRAPHIC IMAGE ENHANCEMENT; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 48949116196     PISSN: 09387994     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00330-008-0942-9     Document Type: Article

References (25)

1. Winer-Muram HT, Rydberg J, Johnson MS, Tarver RD, Williams MD, Shah H, Namyslowski J, Conces D, Jennings SG, Ying J, Trerotola SO, Kopecky KK (2004) Suspected acute pulmonary embolism: Evaluation with multi-detector row CT versus digital subtraction pulmonary arteriography. Radiology 233:806-815
2. Patel S, Kazerooni EA, Cascade PN (2003) Pulmonary embolism: optimization of small pulmonary artery visualization at multi-detector row CT. Radiology 227:455-460
3. Schoepf UJ, Costelo P (2004) CT Angiography for diagnosis of Pulmonary Embolism: State of the Art. Radiology 230:329-337
4. Schoellnast H, Deutschmann AH, Fritz GA, Schaffler GJ, Tillich M (2005) MDCT angiography of the pulmonary arteries: Influence of iodine flow concentration on vessel attenuation and visualization. Am J Roentgenol 184:1935-1939
5. Jones SE, Wittram C (2005) The indeterminate CT pulmonary angiogram: imaging characteristics and patient clinical outcome. Radiology 237:329-337
6. Arakawa H, Kohno T, Hiki T, Kaji Y (2007) CT pulmonary angiography and CT venography: Factors associated with vessel enhancement. Am J Roentgenol 189:156-161
7. Bae KT, Tao C, Gürel S, Hong C, Zhu F, Gebke TA, Milite M, Hildebolt CF (2007) Effect of patient weight and scanning duration on contrast enhancement during pulmonary multidetector CT angiography. Radiology 242:582-589
8. Schoellnast H, Deutschmann HA, Berghold A, Fritz GA, Schaffler GJ, Tillich M (2006) MDCT angiography of the pulmonary arteries: Influence of body weight, body mass index, and scan length at different iodine flow rates. Am J Roentgenol 187:1074-1078
9. Hartmann IJ, Lo RT, Bakker J, de Monye W, van Waes PF, Pattynama PM (2002) Optimal scan delay in spiral CT for the diagnosis of acute pulmonary embolism. J Comput Assist Tomogr 26:21-25
10. Lee CH, Goo JM, Lee HJ, Kim KG, Im JG, Bae KT (2007) Determination of optimal timing window for pulmonary artery MDCT angiography. Am J Roentgenol 188:313-317
11. Yankelevitz DF, Shaham D, Shah A, Rademacker J, Henschke CI (1998) Optimization of contrast delivery for pulmonary CT angiography. Clin Imaging 22:398-403
12. Han JK, Kim AY, Lee KY, Seo JB, Kim TK, Choi BI, Lhee CS, Han MC (2000) Factors influencing vascular and hepatic enhancement at CT: Experimental study on injection protocol using a canine model. J Comput Assist Tomogr 24:400-406
13. Awai K, Takada K, Onishi H, Hori S (2002) Aortic and hepatic enhancement and tumor-to-liver contrast: Analysis of the effect of different concentrations of contrast material at multi-detector row helical CT. Radiology 224:757-763
14. Awai K, Inoue M, Yagyu Y, Watanabe M, Sano T, Nin S, Koike R, Nishimura Y, Yamashita Y (2004) Moderate versus high concentration of contrast material for aortic and hepatic enhancement and tumor-to-liver contrast at multi-detector row CT. Radiology 233:682-688
15. Cademartiri F, de Monye C, Pugliese F, Mollet NR, Runza G, van der Lugt A, Midiri M, de Feyter PJ, Lagalla R, Krestin GP (2006) High iodine concentration contrast material for non-invasive multislice computed tomography coronary angiography: Iopromide 370 versus iomeprol 400. Invest Radiol 41:349-353
16. Setty BN, Sahani DV, Ouellette-Piazzo K, Hahn PF, Shepard JA (2006) Comparison of enhancement, image quality, cost, and adverse reactions using 2 different contrast medium concentrations for routine chest CT on 16-slice MDCT. J Comput Assist Tomogr 30:818-822
17. Rist C, Nikolaou K, Kirchin MA, van Gessel R, Bae KT, von Ziegler F, Knez A, Wintersperger BJ, Reiser MF, Becker CR (2006) Contrast bolus optimization for cardiac 16-slice computed tomography: Comparison of contrast medium formulations containing 300 and 400 milligrams of iodine per millilitre. Invest Radiol 41:460-467
18. Fleischmann D (2003) Use of high-concentration contrast media in multiple-detector-row CT: Principles and rationale. Eur Radiol 13(Suppl5):M14-M20
19. Fleischmann D (2003) High-concentration contrast media in MDCT angiography: Principles and rationale. Eur Radiol 13(Suppl3):N39-N43
20. Sandstede JJ, Werner A, Kaupert C, Roth A, Jenett M, Harz C, Hahn D (2006) A prospective study comparing different iodine concentrations for triphasic multidetector row CT of the upper abdomen. Eur J Radiol 60:95-99
21. Haage P, Schmitz-Rode T, Hübner D, Piroth W, Günther RW (2000) Reduction of contrast material dose and artifacts by a saline flush using a double power injector in helical CT of the thorax. Am J Roentgenol 174:1049-1053
22. Federle MP, Chang PJ, Confer S, Ozgun B (1998) Frequency and effects of extravasation of ionic and nonionic CT contrast media during rapid bolus injection. Radiology 206:637-640
23. Platt JF, Reige KA, Ellis JH (1999) Aortic enhancement during abdominal CT angiography: Correlation with test injections, flow rates, and patient demographics. Am J Roentgenol 172:53-56
24. Bae KT, Heiken JP, Brink JA (1998) Aortic and hepatic contrast medium enhancement at CT. Part II. Effect of reduced cardiac output in a porcine model. Radiology 207:657-662
25. Wildberger JE, Mahnken AH, Sinha AM, Stargardt A, Haage P, Schaller S, Gunther RW (2002) A differentiated approach to the diagnosis of pulmonary embolism and deep venous thrombosis using multi-slice CT. Rofo 174:301-307