-
1
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: from genes to environment
-
Farazi P.A., and DePinho R.A. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat. Rev. Cancer 6 (2006) 674-687
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 674-687
-
-
Farazi, P.A.1
DePinho, R.A.2
-
2
-
-
0036699940
-
Molecular pathogenesis of human hepatocellular carcinoma
-
Thorgeirsson S.S., and Grisham J.W. Molecular pathogenesis of human hepatocellular carcinoma. Nat. Genet. 31 (2002) 339-346
-
(2002)
Nat. Genet.
, vol.31
, pp. 339-346
-
-
Thorgeirsson, S.S.1
Grisham, J.W.2
-
3
-
-
46949106325
-
Mutations in the carboxyl terminus of the X protein of Hepatitis B Virus regulate Wnt-5a expression in hepatoma Huh7 cells: cDNA microarray and proteomic analyses
-
10.1093/carcin/bgn111
-
Liu X.H., Wang L., Zhang S.H., Lin J., Zhang S.M., Feitelson M.A., Gao H.J., and Zhu M.H. Mutations in the carboxyl terminus of the X protein of Hepatitis B Virus regulate Wnt-5a expression in hepatoma Huh7 cells: cDNA microarray and proteomic analyses. Carcinogenesis (2008) 10.1093/carcin/bgn111
-
(2008)
Carcinogenesis
-
-
Liu, X.H.1
Wang, L.2
Zhang, S.H.3
Lin, J.4
Zhang, S.M.5
Feitelson, M.A.6
Gao, H.J.7
Zhu, M.H.8
-
4
-
-
4444222917
-
cDNA microarray analysis of early gene expression profiles associated with hepatitis B virus X protein-mediated hepatocarcinogenesis
-
Ng R.K., Lau C.Y., Lee S.M., Tsui S.K., Fung K.P., and Waye M.M. cDNA microarray analysis of early gene expression profiles associated with hepatitis B virus X protein-mediated hepatocarcinogenesis. Biochem. Biophys. Res. Commun. 322 (2004) 827-835
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.322
, pp. 827-835
-
-
Ng, R.K.1
Lau, C.Y.2
Lee, S.M.3
Tsui, S.K.4
Fung, K.P.5
Waye, M.M.6
-
5
-
-
0025907983
-
HBx gene of hepatitis B virus induces liver cancer in transgenic mice
-
Kim C.M., Koike K., Saito I., Miyamura T., and Jay G. HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 351 (1991) 317-320
-
(1991)
Nature
, vol.351
, pp. 317-320
-
-
Kim, C.M.1
Koike, K.2
Saito, I.3
Miyamura, T.4
Jay, G.5
-
6
-
-
0033058294
-
Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein
-
Yu D.Y., Moon H.B., Son J.K., Jeong S., Yu S.L., Yoon H., Han Y.M., Lee C.S., Park J.S., Lee C.H., Hyun B.H., Murakami S., and Lee K.K. Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein. J. Hepatol. 31 (1999) 123-132
-
(1999)
J. Hepatol.
, vol.31
, pp. 123-132
-
-
Yu, D.Y.1
Moon, H.B.2
Son, J.K.3
Jeong, S.4
Yu, S.L.5
Yoon, H.6
Han, Y.M.7
Lee, C.S.8
Park, J.S.9
Lee, C.H.10
Hyun, B.H.11
Murakami, S.12
Lee, K.K.13
-
7
-
-
0031949796
-
Properties of tumour suppressor p53 in murine hepatocyte lines transformed by hepatitis B virus X protein
-
Schaefer S., Seifer M., Grimmsmann T., Fink L., Wenderhold S., Hohne M.W., and Gerlich W.H. Properties of tumour suppressor p53 in murine hepatocyte lines transformed by hepatitis B virus X protein. J. Gen. Virol. 79 Pt. 4 (1998) 767-777
-
(1998)
J. Gen. Virol.
, vol.79
, Issue.PART 4
, pp. 767-777
-
-
Schaefer, S.1
Seifer, M.2
Grimmsmann, T.3
Fink, L.4
Wenderhold, S.5
Hohne, M.W.6
Gerlich, W.H.7
-
8
-
-
0033593214
-
Differential immediate early gene expression in conditional hepatitis B virus pX-transforming versus nontransforming hepatocyte cell lines
-
Tarn C., Bilodeau M.L., Hullinger R.L., and Andrisani O.M. Differential immediate early gene expression in conditional hepatitis B virus pX-transforming versus nontransforming hepatocyte cell lines. J. Biol. Chem. 274 (1999) 2327-2336
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2327-2336
-
-
Tarn, C.1
Bilodeau, M.L.2
Hullinger, R.L.3
Andrisani, O.M.4
-
9
-
-
0032529463
-
Hepatitis B virus X protein transcription activation domains are neither required nor sufficient for cell transformation
-
Gottlob K., Pagano S., Levrero M., and Graessmann A. Hepatitis B virus X protein transcription activation domains are neither required nor sufficient for cell transformation. Cancer Res. 58 (1998) 3566-3570
-
(1998)
Cancer Res.
, vol.58
, pp. 3566-3570
-
-
Gottlob, K.1
Pagano, S.2
Levrero, M.3
Graessmann, A.4
-
10
-
-
0033607041
-
Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx
-
Sirma H., Giannini C., Poussin K., Paterlini P., Kremsdorf D., and Brechot C. Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx. Oncogene 18 (1999) 4848-4859
-
(1999)
Oncogene
, vol.18
, pp. 4848-4859
-
-
Sirma, H.1
Giannini, C.2
Poussin, K.3
Paterlini, P.4
Kremsdorf, D.5
Brechot, C.6
-
11
-
-
30144444237
-
Blocking of G1/S transition and cell death in the regenerating liver of Hepatitis B virus X protein transgenic mice
-
Wu B.K., Li C.C., Chen H.J., Chang J.L., Jeng K.S., Chou C.K., Hsu M.T., and Tsai T.F. Blocking of G1/S transition and cell death in the regenerating liver of Hepatitis B virus X protein transgenic mice. Biochem. Biophys. Res. Commun. 340 (2006) 916-928
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.340
, pp. 916-928
-
-
Wu, B.K.1
Li, C.C.2
Chen, H.J.3
Chang, J.L.4
Jeng, K.S.5
Chou, C.K.6
Hsu, M.T.7
Tsai, T.F.8
-
12
-
-
0035812298
-
Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway
-
Ahn J.Y., Chung E.Y., Kwun H.J., and Jang K.L. Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway. Gene 275 (2001) 163-168
-
(2001)
Gene
, vol.275
, pp. 163-168
-
-
Ahn, J.Y.1
Chung, E.Y.2
Kwun, H.J.3
Jang, K.L.4
-
13
-
-
0032558845
-
p53-Independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro
-
Terradillos O., Pollicino T., Lecoeur H., Tripodi M., Gougeon M.L., Tiollais P., and Buendia M.A. p53-Independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro. Oncogene 17 (1998) 2115-2123
-
(1998)
Oncogene
, vol.17
, pp. 2115-2123
-
-
Terradillos, O.1
Pollicino, T.2
Lecoeur, H.3
Tripodi, M.4
Gougeon, M.L.5
Tiollais, P.6
Buendia, M.A.7
-
14
-
-
0034761676
-
Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression
-
Qiao L., Leach K., McKinstry R., Gilfor D., Yacoub A., Park J.S., Grant S., Hylemon P.B., Fisher P.B., and Dent P. Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression. Hepatology 34 (2001) 906-917
-
(2001)
Hepatology
, vol.34
, pp. 906-917
-
-
Qiao, L.1
Leach, K.2
McKinstry, R.3
Gilfor, D.4
Yacoub, A.5
Park, J.S.6
Grant, S.7
Hylemon, P.B.8
Fisher, P.B.9
Dent, P.10
-
15
-
-
1542720383
-
Expression of mesenchyme-specific gene HMGA2 in squamous cell carcinomas of the oral cavity
-
Miyazawa J., Mitoro A., Kawashiri S., Chada K.K., and Imai K. Expression of mesenchyme-specific gene HMGA2 in squamous cell carcinomas of the oral cavity. Cancer Res. 64 (2004) 2024-2029
-
(2004)
Cancer Res.
, vol.64
, pp. 2024-2029
-
-
Miyazawa, J.1
Mitoro, A.2
Kawashiri, S.3
Chada, K.K.4
Imai, K.5
-
16
-
-
33845920091
-
Hepatitis B virus sensitizes hepatocytes to TRAIL-induced apoptosis through Bax
-
Liang X., Liu Y., Zhang Q., Gao L., Han L., Ma C., Zhang L., Chen Y.H., and Sun W. Hepatitis B virus sensitizes hepatocytes to TRAIL-induced apoptosis through Bax. J. Immunol. 178 (2007) 503-510
-
(2007)
J. Immunol.
, vol.178
, pp. 503-510
-
-
Liang, X.1
Liu, Y.2
Zhang, Q.3
Gao, L.4
Han, L.5
Ma, C.6
Zhang, L.7
Chen, Y.H.8
Sun, W.9
-
17
-
-
41149093028
-
COOH-terminal deletion of HBx gene is a frequent event in HBV-associated hepatocellular carcinoma
-
Liu X.H., Lin J., Zhang S.H., Zhang S.M., Feitelson M.A., Gao H.J., and Zhu M.H. COOH-terminal deletion of HBx gene is a frequent event in HBV-associated hepatocellular carcinoma. World J. Gastroenterol. 14 (2008) 1346-1352
-
(2008)
World J. Gastroenterol.
, vol.14
, pp. 1346-1352
-
-
Liu, X.H.1
Lin, J.2
Zhang, S.H.3
Zhang, S.M.4
Feitelson, M.A.5
Gao, H.J.6
Zhu, M.H.7
-
18
-
-
0042671276
-
Characterisation of hepatitis B virus X protein mutants in tumour and non-tumour liver cells using laser capture microdissection
-
Iavarone M., Trabut J.B., Delpuech O., Carnot F., Colombo M., Kremsdorf D., Brechot C., and Thiers V. Characterisation of hepatitis B virus X protein mutants in tumour and non-tumour liver cells using laser capture microdissection. J. Hepatol. 39 (2003) 253-261
-
(2003)
J. Hepatol.
, vol.39
, pp. 253-261
-
-
Iavarone, M.1
Trabut, J.B.2
Delpuech, O.3
Carnot, F.4
Colombo, M.5
Kremsdorf, D.6
Brechot, C.7
Thiers, V.8
-
19
-
-
22144498137
-
A proteomics analysis of cellular proteins associated with HBV genotype-specific HBX: potential in identification of early diagnostic markers for HCC
-
Tan T.L., and Chen W.N. A proteomics analysis of cellular proteins associated with HBV genotype-specific HBX: potential in identification of early diagnostic markers for HCC. J. Clin. Virol. 33 (2005) 293-298
-
(2005)
J. Clin. Virol.
, vol.33
, pp. 293-298
-
-
Tan, T.L.1
Chen, W.N.2
-
20
-
-
0035502957
-
Biological impact of natural COOH-terminal deletions of hepatitis B virus X protein in hepatocellular carcinoma tissues
-
Tu H., Bonura C., Giannini C., Mouly H., Soussan P., Kew M., Paterlini-Brechot P., Brechot C., and Kremsdorf D. Biological impact of natural COOH-terminal deletions of hepatitis B virus X protein in hepatocellular carcinoma tissues. Cancer Res. 61 (2001) 7803-7810
-
(2001)
Cancer Res.
, vol.61
, pp. 7803-7810
-
-
Tu, H.1
Bonura, C.2
Giannini, C.3
Mouly, H.4
Soussan, P.5
Kew, M.6
Paterlini-Brechot, P.7
Brechot, C.8
Kremsdorf, D.9
-
21
-
-
33646052005
-
Antisense regulation of expression and transactivation functions of the tumorigenic HBx and c-myc genes
-
Hung L., and Kumar V. Antisense regulation of expression and transactivation functions of the tumorigenic HBx and c-myc genes. Biochem. Biophys. Res. Commun. 344 (2006) 293-299
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.344
, pp. 293-299
-
-
Hung, L.1
Kumar, V.2
-
22
-
-
33745220726
-
Nuclear BCL-10 expression is common in lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia and does not correlate with p65 NF-kappaB activation
-
Merzianu M., Jiang L., Lin P., Wang X., Weber D.M., Vadhan-Raj S., Nguyen M.H., Medeiros L.J., and Bueso-Ramos C.E. Nuclear BCL-10 expression is common in lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia and does not correlate with p65 NF-kappaB activation. Mod. Pathol. 19 (2006) 891-898
-
(2006)
Mod. Pathol.
, vol.19
, pp. 891-898
-
-
Merzianu, M.1
Jiang, L.2
Lin, P.3
Wang, X.4
Weber, D.M.5
Vadhan-Raj, S.6
Nguyen, M.H.7
Medeiros, L.J.8
Bueso-Ramos, C.E.9
-
23
-
-
0037427074
-
MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells
-
Wang X., Jin D.Y., Wong H.L., Feng H., Wong Y.C., and Tsao S.W. MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells. Oncogene 22 (2003) 109-116
-
(2003)
Oncogene
, vol.22
, pp. 109-116
-
-
Wang, X.1
Jin, D.Y.2
Wong, H.L.3
Feng, H.4
Wong, Y.C.5
Tsao, S.W.6
-
24
-
-
4344703256
-
Anthocyanins induce cell cycle perturbations and apoptosis in different human cell lines
-
Lazze M.C., Savio M., Pizzala R., Cazzalini O., Perucca P., Scovassi A.I., Stivala L.A., and Bianchi L. Anthocyanins induce cell cycle perturbations and apoptosis in different human cell lines. Carcinogenesis 25 (2004) 1427-1433
-
(2004)
Carcinogenesis
, vol.25
, pp. 1427-1433
-
-
Lazze, M.C.1
Savio, M.2
Pizzala, R.3
Cazzalini, O.4
Perucca, P.5
Scovassi, A.I.6
Stivala, L.A.7
Bianchi, L.8
-
25
-
-
33846948601
-
The hepatitis B virus X protein promotes hepatocellular carcinoma metastasis by upregulation of matrix metalloproteinases
-
Ou D.P., Tao Y.M., Tang F.Q., and Yang L.Y. The hepatitis B virus X protein promotes hepatocellular carcinoma metastasis by upregulation of matrix metalloproteinases. Int. J. Cancer 120 (2007) 1208-1214
-
(2007)
Int. J. Cancer
, vol.120
, pp. 1208-1214
-
-
Ou, D.P.1
Tao, Y.M.2
Tang, F.Q.3
Yang, L.Y.4
-
26
-
-
2442543090
-
Dystrophin Dp71 is required for neurite outgrowth in PC12 cells
-
Acosta R., Montanez C., Fuentes-Mera L., Gonzalez E., Gomez P., Quintero-Mora L., Mornet D., Alvarez-Salas L.M., and Cisneros B. Dystrophin Dp71 is required for neurite outgrowth in PC12 cells. Exp. Cell Res. 296 (2004) 265-275
-
(2004)
Exp. Cell Res.
, vol.296
, pp. 265-275
-
-
Acosta, R.1
Montanez, C.2
Fuentes-Mera, L.3
Gonzalez, E.4
Gomez, P.5
Quintero-Mora, L.6
Mornet, D.7
Alvarez-Salas, L.M.8
Cisneros, B.9
-
27
-
-
0025358757
-
X antigen polypeptides in the sera of hepatitis B virus-infected patients
-
Feitelson M.A., and Clayton M.M. X antigen polypeptides in the sera of hepatitis B virus-infected patients. Virology 177 (1990) 367-371
-
(1990)
Virology
, vol.177
, pp. 367-371
-
-
Feitelson, M.A.1
Clayton, M.M.2
-
28
-
-
0031460372
-
Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis
-
Elmore L.W., Hancock A.R., Chang S.F., Wang X.W., Chang S., Callahan C.P., Geller D.A., Will H., and Harris C.C. Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis. Proc. Natl. Acad. Sci. USA 94 (1997) 14707-14712
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14707-14712
-
-
Elmore, L.W.1
Hancock, A.R.2
Chang, S.F.3
Wang, X.W.4
Chang, S.5
Callahan, C.P.6
Geller, D.A.7
Will, H.8
Harris, C.C.9
-
29
-
-
34249303417
-
Hepatitis B virus integration, fragile sites, and hepatocarcinogenesis
-
Feitelson M.A., and Lee J. Hepatitis B virus integration, fragile sites, and hepatocarcinogenesis. Cancer Lett. 252 (2007) 157-170
-
(2007)
Cancer Lett.
, vol.252
, pp. 157-170
-
-
Feitelson, M.A.1
Lee, J.2
-
30
-
-
2342484993
-
Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene
-
Kwun H.J., and Jang K.L. Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene. Nucleic Acids Res. 32 (2004) 2202-2213
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 2202-2213
-
-
Kwun, H.J.1
Jang, K.L.2
-
31
-
-
37649020435
-
Ubiquitin-dependent and -independent proteasomal degradation of hepatitis B virus X protein
-
Kim J.H., Sohn S.Y., Benedict Yen T.S., and Ahn B.Y. Ubiquitin-dependent and -independent proteasomal degradation of hepatitis B virus X protein. Biochem. Biophys. Res. Commun. 366 (2008) 1036-1042
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.366
, pp. 1036-1042
-
-
Kim, J.H.1
Sohn, S.Y.2
Benedict Yen, T.S.3
Ahn, B.Y.4
-
32
-
-
34547593907
-
Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: factors contributing to hepatocarcinogenesis
-
Chin R., Earnest-Silveira L., Koeberlein B., Franz S., Zentgraf H., Dong X., Gowans E., Bock C.T., and Torresi J. Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: factors contributing to hepatocarcinogenesis. J. Hepatol. 47 (2007) 325-337
-
(2007)
J. Hepatol.
, vol.47
, pp. 325-337
-
-
Chin, R.1
Earnest-Silveira, L.2
Koeberlein, B.3
Franz, S.4
Zentgraf, H.5
Dong, X.6
Gowans, E.7
Bock, C.T.8
Torresi, J.9
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