Use of cyclohexanedimethanol as a nonflammable organic solvent for industrial scale reversed phase chromatography

Journal of Chromatography A

Volumn 1202, Issue 1, 2008, Pages 107-110

  Hunter, Alan K ^a   Hoeltzli, Sydney D ^a   Johnson, Gary V ^a   Gustafson, Mark E ^a   Ho, Sa V ^a  

^a PFIZER INC   (United States)

Author keywords

Apolipoprotein A IMilano; Cyclohexanedimethanol; Nonflammable; Reversed phase chromatography; Solvent

Indexed keywords

CHEMICALS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; FLUIDS; LITHIUM BATTERIES; ORGANIC COMPOUNDS; SOLVENTS;

APOLIPOPROTEIN A-I (APOA-I); INDUSTRIAL SCALE; NONFLAMMABLE; PILOT SCALE; REVERSED PHASE CHROMATOGRAPHY (RPC);

ORGANIC SOLVENTS;

APOLIPOPROTEIN A; CELL PROTEIN; CYCLOHEXANEDIMETHANOL; INDUSTRIAL CHEMICAL; ORGANIC SOLVENT; WATER;

ARTICLE; ESCHERICHIA COLI; HYPOBARISM; INDUSTRY; PRIORITY JOURNAL; PROTEIN PURIFICATION; REVERSED PHASE LIQUID CHROMATOGRAPHY; VISCOSITY;

APOLIPOPROTEIN A-I; CHROMATOGRAPHY, LIQUID; CYCLOHEXANES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ORGANIC CHEMICALS; RECOMBINANT PROTEINS; SOLVENTS;

EID: 48949114912     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.06.032     Document Type: Article

References (10)

1. Kroeff E.P., Owens R.A., Campbell E.L., Johnson R.D., and Marks H.I. J. Chromatogr. 461 (1989) 45
2. Olson C.V., Reifsnyder D.H., Canova-Davis E., Ling V.T., and Builder S.E. J. Chromatogr. A 675 (1994) 101
3. Reddy P.K., Reddy S.G., Narala V.R., Majee S.S., Konda S., Gunwar S., and Reddy R.C. Prot. Exp. Purif. 52 (2007) 123
4. Fahrner R.L., Lester P.M., Blank G.S., and Reifsnyder D.H. J. Chromatogr. A 830 (1999) 127
5. R.L. Fahrner, D. Reifsnyder, United States Patent # 6,265,542.
6. T.A. Hauser, K.J. Hayenga, United States Patent # 6,966,992.
7. Donovan J.M., Benedek G.B., and Carey M.C. Biochemistry 26 (1987) 8116
8. Calabresi L., Vecchio G., Longhi R., Gianazza E., Palm G., Wadensten H., Hammarstrom A., Olsson A., Karlstrom A., Sejlitz T., Ageland H., Sirtori C.R., and Franceschini G. J. Biol. Chem. 269 (1994) 32168
9. Suurkuusk M., and Hallen D. Eur. J. Biochem. 264 (1999) 183
10. Vitello L.B., and Scanu A.M. J. Biol. Chem. 251 (1976) 1131