Chiral ligand 2-(2′-piperidinyl)pyridine: synthesis, resolution and application in asymmetric diethylzinc addition to aldehydes

Tetrahedron Asymmetry

Volumn 19, Issue 13, 2008, Pages 1572-1575

  Cheng, Yan Qin ^a   Bian, Zheng ^a   Kang, Chuan Qing ^a   Guo, Hai Quan ^a   Gao, Lian Xun ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2' PIPERIDINYL)PYRIDINE; ALCOHOL; ALDEHYDE; DIETHYLZINC; PYRIDINE DERIVATIVE; TARTARIC ACID;

ADDITION REACTION; ARTICLE; ASYMMETRIC CATALYSIS; ASYMMETRIC SYNTHESIS; BENZYLATION; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHIRALITY; DEBENZYLATION; ENANTIOMER; ENANTIOSELECTIVITY; HYDROGENATION; NONHUMAN; OPTICAL RESOLUTION; PRIORITY JOURNAL; X RAY ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 48949114888     PISSN: 09574166     EISSN: 1362511X     Source Type: Journal    
DOI: 10.1016/j.tetasy.2008.06.005     Document Type: Article

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36. Enantiomeric excess analysis was determined by HPLC with a Chiralcel-OD column at 254 nm (hexane/iPrOH in the ratio of 97/3, flow 0.5 mL/min; the retention time of (R)-2 was 17.6 min, while that of (S)-2 was 19.5 min).
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