Effects of GM-CSF gene transfer using silica-nanoparticles as a vehicle on white blood cell production in dogs

Experimental Hematology

Volumn 36, Issue 7, 2008, Pages 807-815

  Choi, Eun Wha ^a,b   Shin, Il Seob ^b   Chae, Young Jin ^b   Koo, Hye Cheong ^a,b   Lee, Jong Hwa ^b   Chung, Tae Ho ^b   Park, Yong Ho ^a,b   Kim, Dae Yong ^a,b   Hwang, Cheol Yong ^a,b   Lee, Chang Woo ^b   Youn, Hwa Young ^a,b  

^a KRF Zoonotic Disease Priority Research Institute

^b Konkuk University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; NANOPARTICLE; NEUTRALIZING ANTIBODY; SILICON DIOXIDE;

ADENYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARE LYMPHOCYTE SYNDROME; BONE MARROW SUPPRESSION; CONTROLLED STUDY; CYTOMEGALOVIRUS; FLOW CYTOMETRY; GENE CONSTRUCT; GENE SEQUENCE; GENE TARGETING; GENE TRANSFER; IN VIVO STUDY; LEUKOCYTE; LEUKOCYTE DIFFERENTIAL COUNT; LEUKOPENIA; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIMIAN VIRUS 40;

ACUTE DISEASE; ANIMALS; DOGS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; GRANULOCYTES; HISTOCOMPATIBILITY ANTIGENS CLASS II; LEUKOCYTES, MONONUCLEAR; LEUKOPENIA; NANOPARTICLES; SILICON DIOXIDE;

CANIS FAMILIARIS; CYTOMEGALOVIRUS; SIMIAN VIRUS 40;

EID: 48949111897     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2008.01.007     Document Type: Article

References (20)

1. Ogilvie G.K., Obradovich J.E., Cooper M.F., Walters L.M., Salman M.D., and Boone T.C. Use of recombinant canine granulocyte colony-stimulating factor to decrease myelosuppression associated with the administration of mitoxantrone in the dog. J Vet Intern Med 6 (1992) 44-47
2. Quesniaux V.F.J., and Jones T.C. Granulocyte-macrophage colony stimulating factor. In: Thomson A.W. (Ed). The Cytokine Handbook. 3rd ed. (1998), Academic Press, London 637-659
3. Shin I.S., Nam M.J., Park S.J., Youn H.Y., and Han H.R. Cloning of canine GM-CSF and SCF genes. J Vet Sci. 2 (2001) 159-166
4. Makrides S.C. Strategies for achieving high-level expression of genes in Escherichia coli. Microbiol Rev. 60 (1996) 512-538
5. Choi J.H., Keum K.C., and Lee S.Y. Production of recombinant proteins by high cell density culture of Escherichia coli. Chem Eng Sci. 61 (2006) 876-885
6. Choi E.W., Shin I.S., Youn H.Y., et al. Gene therapy using non-viral peptide vector in a canine systemic lupus erythematosus model. Vet Immunol Immunopathol 103 (2005) 223-233
7. Bharali D.J., Klejbor I., Stachowiak E.K., et al. Organically modified silica-nanoparticles: a nonviral vector for in vivo gene delivery and expression in the brain. Proc Natl Acad Sci U S A 102 (2005) 11539-11544
8. Choi E.W., Shin I.S., Bhang D.H., et al. Hormonal change and cytokine mRNA expression in peripheral blood mononuclear cells during the development of canine autoimmune thyroiditis. Clin Exp Immunol 146 (2006) 101-108
9. Tangney M., Casey G., Larkin J.O., et al. Non-viral in vivo immune gene therapy of cancer: combined strategies for treatment of systemic disease. Cancer Immunol Immunother 55 (2006) 1443-1450
10. Mishu L., Callahan G., Allebban Z., et al. Effects of recombinant canine granulocyte colony-stimulating factor on white blood cell production in clinically normal and neutropenic dogs. J Am Vet Med Assoc. 200 (1992) 1957-1964
11. Ulich T.R., del Castillo J., McNiece I., Watson L., Yin S.M., and Andresen J. Hematologic effects of recombinant murine granulocyte-macrophage colony-stimulating factor on the peripheral blood and bone marrow. Am J Pathol 137 (1990) 369-376
12. Kim J.S., Yoon T.J., Yu K.N., et al. Toxicity and tissue distribution of magnetic nanoparticles in mice. Toxicol Sci. 89 (2006) 338-347
13. Cartmell T., Southgate T., Rees G.S., Castro M.G., Lowenstein P.R., and Luheshi G.N. Interleukin-1 mediates a rapid inflammatory response after injection of adenoviral vectors into the brain. J Neurosci 19 (1999) 1517-1523
14. Lloyd A.R., and Oppenheim J.J. Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response. Immunol Today 13 (1992) 169-172
15. Gosselin E.J., Wardwell K., Rigby W.F., and Guyre P.M. Induction of MHC class II on human polymorphonuclear neutrophils by granulocyte/macrophage colony-stimulating factor, IFN-gamma, and IL-3. J Immunol 151 (1993) 1482-1490
16. Okuda K., Neely B.C., and David C.S. Expression of H-2 and Ia antigens on mouse peritoneal neutrophils. Transplantation 28 (1979) 354-356
17. Fitzgerald J.E., Sonis S.T., Rodrick M.L., and Wilson R.E. Interaction of Ia antigen-bearing polymorphonuclear leukocytes and murine splenocytes. Inflammation 7 (1983) 25-33
18. Gangi E., Vasu C., Cheatem D., and Prabhakar B.S. IL-10-producing CD4+CD25+ regulatory T cells play a critical role in granulocyte-macrophage colony-stimulating factor-induced suppression of experimental autoimmune thyroiditis. J Immunol 174 (2005) 7006-7013
19. Keller P., and Smalling R. Granulocyte colony stimulating factor: animal studies for risk assessment. Int Rev Exp Pathol 34 (1993) 173-188
20. Antman K.S., Griffin J.D., Elias A., et al. Effect of recombinant human granulocyte-macrophage colony-stimulating factor on chemotherapy-induced myelosuppression. N Engl J Med 319 (1988) 593-598