-
1
-
-
0035896642
-
Hepcidin, A urinary antimicrobial peptide synthesized in the liver
-
Park CH, Valore EV, Waring AJ & Ganz T, Hepcidin, A urinary antimicrobial peptide synthesized in the liver. J Biol Chem, 2001; 276: 7806-10.
-
(2001)
J Biol Chem
, vol.276
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
Ganz, T.4
-
2
-
-
0034284595
-
LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity
-
Krause A, Neitz S, Magert HJ & al, LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. FEBS Lett, 2000; 480: 147-50.
-
(2000)
FEBS Lett
, vol.480
, pp. 147-150
-
-
Krause, A.1
Neitz, S.2
HJ, M.3
-
3
-
-
0035902605
-
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
-
Nicolas G, Bennoun M, Devaux I & al, Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA, 2001; 98: 8780-5.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8780-8785
-
-
Nicolas, G.1
Bennoun, M.2
Devaux, I.3
-
4
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is oevrexpressed during iron overload
-
Pigeon C, Ilyin G, Courselaud B & al, A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is oevrexpressed during iron overload. J Biol Chem, 2001; 276: 7811-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
-
5
-
-
0037007064
-
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
-
Nicolas G, Bennoun M, Porteu A & al, Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci USA, 2002; 99: 4596-601.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4596-4601
-
-
Nicolas, G.1
Bennoun, M.2
Porteu, A.3
-
6
-
-
13544252463
-
Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia
-
Rivera S, Liu L, Nemeth E & al, Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood, 2005; 105: 1797-802.
-
(2005)
Blood
, vol.105
, pp. 1797-1802
-
-
Rivera, S.1
Liu, L.2
Nemeth, E.3
-
7
-
-
19544386871
-
Hepcidin in iron disorders
-
Papanikolau G, Tzilianos M, Christakis JI & al, Hepcidin in iron disorders. Blood, 2005; 105: 4103-5.
-
(2005)
Blood
, vol.105
, pp. 4103-4105
-
-
Papanikolau, G.1
Tzilianos, M.2
JI, C.3
-
8
-
-
53849104983
-
Meauring serum hepcidin concentrations. Nature Clin Pract
-
Kemna EHJM, Tjalsma H, Wetzels JF & Swinkels DW, Meauring serum hepcidin concentrations. Nature Clin Pract Gastroenterol Hepatol, 2004; 1: 39-45.
-
(2004)
Gastroenterol Hepatol
, vol.1
, pp. 39-45
-
-
Kemna, E.H.J.M.1
Tjalsma, H.2
Wetzels, J.F.3
Swinkels, D.W.4
-
9
-
-
0038662619
-
Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein
-
Nemeth E, Valore EV, Territo M & al, Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood, 2003; 101: 2461-3.
-
(2003)
Blood
, vol.101
, pp. 2461-2463
-
-
Nemeth, E.1
Valore, E.V.2
Territo, M.3
-
10
-
-
24144459870
-
Identification of an intestinal heme transporter
-
Shayeghi M, Latunde-Dada GO, Oakhill JS & al, Identification of an intestinal heme transporter. Cell, 2005; 122: 789-801.
-
(2005)
Cell
, vol.122
, pp. 789-801
-
-
Shayeghi, M.1
Latunde-Dada, G.O.2
JS, O.3
-
11
-
-
13444252281
-
Iron release from macrophages after erythro-phagocytosis is up-regulated by ferroportin 1 over expression and down-regulated by hepcidin
-
Knutson MD, Oukka M, Koss LM & al, Iron release from macrophages after erythro-phagocytosis is up-regulated by ferroportin 1 over expression and down-regulated by hepcidin. Proc Natl Acad Sci USA, 2005; 102: 1324-8.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1324-1328
-
-
Knutson, M.D.1
Oukka, M.2
LM, K.3
-
12
-
-
0037131264
-
Regulation of reticuloendothelial iron transporter MTP1 (Slc11a3) by inflammation
-
Yang Y, Liu X-b, Quinones M & al, Regulation of reticuloendothelial iron transporter MTP1 (Slc11a3) by inflammation. J Biol Chem, 2002; 277: 39786-91.
-
(2002)
J Biol Chem
, vol.277
, pp. 39786-39791
-
-
Yang, Y.1
Liu, X.-B.2
Quinones, M.3
-
13
-
-
0033861745
-
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
-
McKie AT, Marciani P, Rolfs A & al, A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell, 2000; 5: 299-309.
-
(2000)
Mol Cell
, vol.5
, pp. 299-309
-
-
McKie, A.T.1
Marciani, P.2
Rolfs, A.3
-
14
-
-
15044358801
-
Hephaestin-a ferroxidase of cellular iron export
-
Petrak J & Vyoral D, Hephaestin-a ferroxidase of cellular iron export. Int J Biochem Cell Biol, 2005; 37: 1173-8.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 1173-1178
-
-
Petrak, J.1
Vyoral, D.2
-
15
-
-
10844258104
-
Hepcidin regulates iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J & al, Hepcidin regulates iron efflux by binding to ferroportin and inducing its internalization. Science, 2004; 306: 2090-3.
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
-
16
-
-
28444488323
-
The presence of the ion exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and downregulated by hepcidin
-
Delaby C, Pilard N, Goncalves AS & al, The presence of the ion exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and downregulated by hepcidin. Blood, 2005; 106: 3979-84.
-
(2005)
Blood
, vol.106
, pp. 3979-3984
-
-
Delaby, C.1
Pilard, N.2
AS, G.3
-
17
-
-
34548594676
-
Hepcidin and its role in regulating systemic ion metabolism
-
Ganz T, Hepcidin and its role in regulating systemic ion metabolism. Hematology, 2006: 29-35.
-
(2006)
Hematology
, pp. 29-35
-
-
Ganz, T.1
-
18
-
-
0742272103
-
The ferroportin disease
-
Pietrangelo A, The ferroportin disease. Blood cells Mol Dis, 2004; 32: 131-8.
-
(2004)
Blood cells Mol Dis
, vol.32
, pp. 131-138
-
-
Pietrangelo, A.1
-
19
-
-
20844462571
-
In vitro functional analysis of human ferroportin (FPN) and hemochromatosis- associated FPN mutations
-
Schimanski LM, Drakesmith H, Merryweather-Clarke AT & al, In vitro functional analysis of human ferroportin (FPN) and hemochromatosis- associated FPN mutations. Blood, 2005; 105: 4096-4102.
-
(2005)
Blood
, vol.105
, pp. 4096-4102
-
-
Schimanski, L.M.1
Drakesmith, H.2
AT, M.-C.3
-
20
-
-
28444466958
-
Understanding iron homeostasis through genetic analysis of hemochromatosis and related disorders
-
Camaschella C, Understanding iron homeostasis through genetic analysis of hemochromatosis and related disorders. Blood, 2005; 106: 3710-7.
-
(2005)
Blood
, vol.106
, pp. 3710-3717
-
-
Camaschella, C.1
-
21
-
-
33750133047
-
Regulation of iron metabolism by hepcidin
-
Nemeth E & Ganz T, Regulation of iron metabolism by hepcidin. Ann Rev Nutr, 2006; 26: 323-42.
-
(2006)
Ann Rev Nutr
, vol.26
, pp. 323-342
-
-
Nemeth, E.1
Ganz, T.2
-
22
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto A, Papnicolau G, Politou N & al, Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet, 2003; 33: 21-2.
-
(2003)
Nat Genet
, vol.33
, pp. 21-22
-
-
Roetto, A.1
Papnicolau, G.2
Politou, N.3
-
23
-
-
27144459908
-
Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin
-
Lin L, Goldberg YP & Ganz T, Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin. Blood, 2005; 106: 2884-9.
-
(2005)
Blood
, vol.106
, pp. 2884-2889
-
-
Lin, L.1
Goldberg, Y.P.2
Ganz, T.3
-
24
-
-
33745898241
-
Bone morphogenetic proteins 2, 4 and 9 stimulate murine hepcidine 1 expression independently of Hfe, transferring receptor 2 (Tfr2), and IL-6
-
Truksa J, Peng H, Lee P & al, Bone morphogenetic proteins 2, 4 and 9 stimulate murine hepcidine 1 expression independently of Hfe, transferring receptor 2 (Tfr2), and IL-6. Proc Natl Acad Sci USA, 2006; 103: 10289-93.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 10289-10293
-
-
Truksa, J.1
Peng, H.2
Lee, P.3
-
25
-
-
33646370235
-
Bone morphogenetic protein signaling by hemojuvekin regulates hepcidin expression
-
Babitt JL, Huang FW, Wrighting DM & al, Bone morphogenetic protein signaling by hemojuvekin regulates hepcidin expression. Nature Genetics, 2006; 38, 531-9.
-
(2006)
Nature Genetics
, vol.38
, pp. 531-539
-
-
Babitt, J.L.1
Huang, F.W.2
DM, W.3
-
26
-
-
8344235994
-
Hepcidin: Inflammation's iron curtain
-
McGarth Jr H & Rigby PG, Hepcidin: inflammation's iron curtain. Rheumatology, 2004; 43: 1323-5.
-
(2004)
Rheumatology
, vol.43
, pp. 1323-1325
-
-
McGarth Jr, H.1
Rigby, P.G.2
-
27
-
-
1842577545
-
Prevalence and outcomes of anemia in cancer: A systematic review of the literature
-
Knight K, Wade S & Balducci L, Prevalence and outcomes of anemia in cancer: a systematic review of the literature. Am J Med, 2004; 116 (Suppl. 7A): 11-16S.
-
(2004)
Am J Med
, vol.116
, Issue.SUPPL. 7A
-
-
Knight, K.1
Wade, S.2
Balducci, L.3
-
28
-
-
85047693999
-
Anemia of inflammation: The cytokine-hepcidine link
-
Andrews NC, Anemia of inflammation: the cytokine-hepcidine link J Clin Invest, 2004; 113: 1251-3.
-
(2004)
J Clin Invest
, vol.113
, pp. 1251-1253
-
-
NC, A.1
-
29
-
-
2342510407
-
IL-6 mediate hypoferremia of inflammation by inducing regulatory hormone hepcidin
-
Nemeth E, Rivera S, Gabayan V & al, IL-6 mediate hypoferremia of inflammation by inducing regulatory hormone hepcidin. J Clin Invest, 2004; 113: 1271-6.
-
(2004)
J Clin Invest
, vol.113
, pp. 1271-1276
-
-
Nemeth, E.1
Rivera, S.2
Gabayan, V.3
-
30
-
-
33751175421
-
Interleukin-6 induces hepcidin expression through STAS3
-
Wrighting DM & Andrews NC, Interleukin-6 induces hepcidin expression through STAS3. Blood, 2006; 108: 3204-9.
-
(2006)
Blood
, vol.108
, pp. 3204-3209
-
-
Wrighting, D.M.1
Andrews, N.C.2
-
31
-
-
53849090507
-
Hepcidin is the principle mediastor of asnemia of inflammation
-
Montreal
-
Rivera S, Hepcidin is the principle mediastor of asnemia of inflammation. Proc Am Coll Chest Physicians Anuual Meeting, 2005, Montreal.
-
(2005)
Proc Am Coll Chest Physicians Anuual Meeting
-
-
Rivera, S.1
-
32
-
-
13844307889
-
Regulation of hepcidine transcription by interleukin-1 and interleukin-6
-
Lee P, Peng H, Gelbart T & al, Regulation of hepcidine transcription by interleukin-1 and interleukin-6. Proc. Natl. Acad. Sci. U.S.A., 2005; 102: 1906-10.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 1906-1910
-
-
Lee, P.1
Peng, H.2
Gelbart, T.3
-
33
-
-
0027978341
-
Effects of recombinant human interlueukin-6 in cancer patients: A phase I-II study
-
van Gameren MM, Willemse PH, Mulder NH & al, Effects of recombinant human interlueukin-6 in cancer patients: a phase I-II study. Blood, 1994; 84: 1434-41.
-
(1994)
Blood
, vol.84
, pp. 1434-1441
-
-
van Gameren, M.M.1
Willemse, P.H.2
NH, M.3
-
34
-
-
0037111732
-
Inappropriate expression of hepcidin is associated with iron refractory anemia: Implications for the anemia of chronic disease
-
Weinstein DA, Roy CN, Fleming M & al, Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood, 2002; 100: 3776-81.
-
(2002)
Blood
, vol.100
, pp. 3776-3781
-
-
Weinstein, D.A.1
Roy, C.N.2
Fleming, M.3
-
35
-
-
1342263728
-
Hepcidin: A molecular link between inflammation and anemia
-
Deicher R & Hörl WH, Hepcidin: a molecular link between inflammation and anemia. Nephrol Dial Transplant, 2004; 19: 521-4.
-
(2004)
Nephrol Dial Transplant
, vol.19
, pp. 521-524
-
-
Deicher, R.1
Hörl, W.H.2
-
36
-
-
0347356639
-
Hepcidin, the recently identified peptide that appears to regulate iron absorption
-
Leong W-I & Lönnerdal B, Hepcidin, the recently identified peptide that appears to regulate iron absorption. J Nutr, 2004; 134: 1-4.
-
(2004)
J Nutr
, vol.134
, pp. 1-4
-
-
Leong, W.-I.1
Lönnerdal, B.2
-
37
-
-
0041672570
-
Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation
-
Ganz T, Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood, 2003; 102: 783-8.
-
(2003)
Blood
, vol.102
, pp. 783-788
-
-
Ganz, T.1
|