메뉴 건너뛰기




Volumn 31, Issue 8, 2008, Pages 1119-1126

Hypocretin receptor expression in canine and murine narcolepsy models and in hypocretin-ligand deficient human narcolepsy

Author keywords

Cataplexy; Dog; Human; Hypocretin orexin; Hypocretin orexin receptors; Mice; Narcolepsy; RT PCR

Indexed keywords

OREXIN 1 RECEPTOR; OREXIN 2 RECEPTOR;

EID: 48949095544     PISSN: 01618105     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (41)

References (20)
  • 1
    • 0030955520 scopus 로고    scopus 로고
    • Pharmacological aspects of human and canine narcolepsy
    • Nishino S, Mignot E. Pharmacological aspects of human and canine narcolepsy. Prog Neurobiol 1997;52:27-78.
    • (1997) Prog Neurobiol , vol.52 , pp. 27-78
    • Nishino, S.1    Mignot, E.2
  • 3
    • 0033529520 scopus 로고    scopus 로고
    • The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
    • Lin L, Faraco J, Li R, et al. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell 1999;98:365-76.
    • (1999) Cell , vol.98 , pp. 365-376
    • Lin, L.1    Faraco, J.2    Li, R.3
  • 4
    • 0034984017 scopus 로고    scopus 로고
    • Hypocretin levels in sporadic and familial cases of canine narcolepsy
    • Ripley B, Fujiki N, Okura M, Mignot E, Nishino S. Hypocretin levels in sporadic and familial cases of canine narcolepsy. Neurobiol Dis 2001;8:525-34.
    • (2001) Neurobiol Dis , vol.8 , pp. 525-534
    • Ripley, B.1    Fujiki, N.2    Okura, M.3    Mignot, E.4    Nishino, S.5
  • 5
    • 0034992322 scopus 로고    scopus 로고
    • Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity
    • Hara J, Beuckmann CT, Nambu T, et al. Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity. Neuron 2001;30:345-54.
    • (2001) Neuron , vol.30 , pp. 345-354
    • Hara, J.1    Beuckmann, C.T.2    Nambu, T.3
  • 6
    • 0033588184 scopus 로고    scopus 로고
    • Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
    • Chemelli RM, Willie JT, Sinton CM, et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 1999;98:437-51.
    • (1999) Cell , vol.98 , pp. 437-451
    • Chemelli, R.M.1    Willie, J.T.2    Sinton, C.M.3
  • 8
    • 0033826856 scopus 로고    scopus 로고
    • A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
    • Peyron C, Faraco J, Rogers W, et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 2000;6:991-7.
    • (2000) Nat Med , vol.6 , pp. 991-997
    • Peyron, C.1    Faraco, J.2    Rogers, W.3
  • 9
    • 0033710848 scopus 로고    scopus 로고
    • Reduced number of hypocretin neurons in human narcolepsy
    • Thannickal TC, Moore RY, Nienhuis R, et al. Reduced number of hypocretin neurons in human narcolepsy. Neuron 2000;27:469-74.
    • (2000) Neuron , vol.27 , pp. 469-474
    • Thannickal, T.C.1    Moore, R.Y.2    Nienhuis, R.3
  • 10
    • 24944518715 scopus 로고    scopus 로고
    • Concomitant loss of dynorphin, NARP, and orexin in narcolepsy
    • Crocker A, Espana RA, Papadopoulou M, et al. Concomitant loss of dynorphin, NARP, and orexin in narcolepsy. Neurology 2005;65:1184-8.
    • (2005) Neurology , vol.65 , pp. 1184-1188
    • Crocker, A.1    Espana, R.A.2    Papadopoulou, M.3
  • 12
    • 1842584959 scopus 로고    scopus 로고
    • Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice
    • Mieda M, Willie JT, Hara J, Sinton CM, Sakurai T, Yanagisawa M. Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice. Proc Natl Acad Sci U S A 2004;101:4649-54.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4649-4654
    • Mieda, M.1    Willie, J.T.2    Hara, J.3    Sinton, C.M.4    Sakurai, T.5    Yanagisawa, M.6
  • 13
    • 0043128708 scopus 로고    scopus 로고
    • Pattern of hypocretin (orexin) soma and axon loss, and gliosis, in human narcolepsy
    • Thannickal TC, Siegel JM, Nienhuis R, Moore RY. Pattern of hypocretin (orexin) soma and axon loss, and gliosis, in human narcolepsy. Brain Pathol 2003;13:340-51.
    • (2003) Brain Pathol , vol.13 , pp. 340-351
    • Thannickal, T.C.1    Siegel, J.M.2    Nienhuis, R.3    Moore, R.Y.4
  • 14
    • 1642382070 scopus 로고    scopus 로고
    • Effects of IV and ICV hypocretin-1 (orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin ligand deficient narcoleptic dog
    • Fujiki N, Ripley B, Yoshida Y, Mignot E, Nishino S. Effects of IV and ICV hypocretin-1 (orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin ligand deficient narcoleptic dog. Sleep 2003;6:953-9.
    • (2003) Sleep , vol.6 , pp. 953-959
    • Fujiki, N.1    Ripley, B.2    Yoshida, Y.3    Mignot, E.4    Nishino, S.5
  • 15
    • 0034332572 scopus 로고    scopus 로고
    • Prepro-hypocretin (prepro-orexin) expression is unaffected by short- term sleep deprivation in rats and mice
    • Terao A, Peyron C, Ding J et al. Prepro-hypocretin (prepro-orexin) expression is unaffected by short- term sleep deprivation in rats and mice. Sleep 2000;23:867-74.
    • (2000) Sleep , vol.23 , pp. 867-874
    • Terao, A.1    Peyron, C.2    Ding, J.3
  • 16
    • 20344399217 scopus 로고    scopus 로고
    • American Academy of Sleep Medicine, 2nd ed, diagnostic and coding manual. Westchester, IL: American Academy of Sleep Medicine
    • American Academy of Sleep Medicine. International classification of sleep disorders, 2nd ed.: diagnostic and coding manual. Westchester, IL: American Academy of Sleep Medicine, 2005.
    • (2005) International classification of sleep disorders
  • 17
    • 0035908286 scopus 로고    scopus 로고
    • Differential expression of orexin receptors 1 and 2 in the rat brain
    • Marcus JN, Aschkenasi CJ, Lee CE, et al. Differential expression of orexin receptors 1 and 2 in the rat brain. J Comp Neurol 2001;435:6-25.
    • (2001) J Comp Neurol , vol.435 , pp. 6-25
    • Marcus, J.N.1    Aschkenasi, C.J.2    Lee, C.E.3
  • 18
    • 0032402181 scopus 로고    scopus 로고
    • Neurons containing hypocretin (orexin) project to multiple neuronal systems
    • Peyron C, Tighe DK, van den Pol AN, et al. Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci 1998;18:9996-10015.
    • (1998) J Neurosci , vol.18 , pp. 9996-10015
    • Peyron, C.1    Tighe, D.K.2    van den Pol, A.N.3
  • 19
    • 0036293837 scopus 로고    scopus 로고
    • Hypocretin stimulates [(35)S]GTP gamma S binding in Hcrtr 2-transfected cell lines and in brain homogenate
    • Shiba T, Ozu M, Yoshida Y, Mignot E, Nishino S. Hypocretin stimulates [(35)S]GTP gamma S binding in Hcrtr 2-transfected cell lines and in brain homogenate. Biochem Biophys Res Commun 2002;294:615-20.
    • (2002) Biochem Biophys Res Commun , vol.294 , pp. 615-620
    • Shiba, T.1    Ozu, M.2    Yoshida, Y.3    Mignot, E.4    Nishino, S.5
  • 20
    • 0038724250 scopus 로고    scopus 로고
    • Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: Molecular genetic dissection of Non-REM and REM sleep regulatory processes
    • Willie JT, Chemelli RM, Sinton CM et al. Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes. Neuron 2003; 38: 715-30.
    • (2003) Neuron , vol.38 , pp. 715-730
    • Willie, J.T.1    Chemelli, R.M.2    Sinton, C.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.