Efficient mining of myxobacterial metabolite profiles enabled by liquid chromatography-electrospray ionisation-time-of-flight mass spectrometry and compound-based principal component analysis

Analytica Chimica Acta

Volumn 624, Issue 1, 2008, Pages 97-106

  Krug, Daniel ^a   Zurek, Gabriela ^b   Schneider, Birgit ^b   Garcia, Ronald ^a   Müller, Rolf ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b BRUKER DALTONIK GMBH   (Germany)

Author keywords

High resolution mass spectrometry; Myxobacteria; Natural products; Principal component analysis; Secondary metabolites

Indexed keywords

ARSENIC COMPOUNDS; BIOMOLECULES; BODY FLUIDS; CHLORINE COMPOUNDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; FINANCIAL DATA PROCESSING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION OF LIQUIDS; ISOTOPES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLITES; MINING; RAW MATERIALS; SENSITIVITY ANALYSIS; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS;

BIOLOGICAL ACTIVITIES; DATA-SETS; ELECTRO SPRAYING; HIGH CONFIDENCE; HIGH RESOLUTIONS; HIGH-RESOLUTION MASS SPECTROMETRY; ISOTOPIC PATTERNS; MASS DATA; MASS POSITION; METABOLITE PROFILING; METABOLOMES; MOLECULAR FORMULAE; MYXOBACTERIA; NATURAL PRODUCTS; NOVEL COMPOUNDS; PRINCIPAL COMPONENT ANALYSIS (PCA); PRINCIPAL COMPONENTS; PRIORITIZATION; RAPID IDENTIFICATION; SECONDARY METABOLITES; STATISTICAL TOOLS; TARGET SCREENING; TIME-OF FLIGHT MASS SPECTROMETRY; TOF MEASUREMENTS;

PRINCIPAL COMPONENT ANALYSIS;

NATURAL PRODUCT;

ACCURACY; ARTICLE; BIOLOGICAL ACTIVITY; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MEASUREMENT; METABOLITE; MYXOCOCCALES; MYXOCOCCUS; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; TIME OF FLIGHT MASS SPECTROMETRY;

BIOLOGICAL PRODUCTS; CHROMATOGRAPHY, LIQUID; MYXOCOCCUS; PRINCIPAL COMPONENT ANALYSIS; QUALITY CONTROL; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

MYXOCOCCALES; MYXOCOCCUS; PROKARYOTA;

EID: 48949091007     PISSN: 00032670     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aca.2008.06.036     Document Type: Article

References (32)

1. Baker D.D., Chu M., Oza U., and Rajgarhia V. Nat. Prod. Rep. 24 (2007) 1225-1244
2. Grabley S., and Thiericke R. The impact of natural products on drug discovery. In: Grabley S., and Thiericke R. (Eds). Drug Discovery from Nature (1999), Springer, Berlin 3-37
3. Koehn F.E., and Carter G.T. Nat. Rev. Drug Discov. 4 (2005) 206-220
4. Baltz R.H. J. Ind. Microbiol. Biotechnol. 33 (2006) 507-513
5. Clardy J., Fischbach M.A., and Walsh C.T. Nat. Biotechnol. 24 (2006) 1541-1550
6. Reichenbach H. J. Ind. Microbiol. Biotechnol. 27 (2001) 149-156
7. Gerth K., Pradella S., Perlova O., Beyer S., and Müller R. J. Biotechnol. 106 (2003) 233-253
8. Reichenbach H., and Höfle G. Myxobacteria as producers of secondary metabolites. In: Grabley S., and Thiericke R. (Eds). Drug Discovery from Nature (1999), Springer, Berlin 149-179
9. Höfle G., and Reichenbach H. Epothilone, a myxobacterial metabolite with promising antitumor activity. In: Cragg G.M., Kingston D.G., and Newman D.J. (Eds). Anticancer Agents from Natural Products (2005), Taylor & Francis, Boca Raton 413-450
10. Bode H.B., and Müller R. Angew. Chem. Int. Ed. 44 (2005) 6828-6846
11. Meiser P., Bode H.B., and Müller R. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 19128-19133
12. Dettmer K., Aronov P.A., and Hammock B.D. Mass Spectrom. Rev. 26 (2007) 51-78
13. Smedsgaard J., and Nielsen J. J. Exp. Bot. 56 (2005) 273-286
14. Villas-Boas S.G., Mas S., Akesson M., Smedsgaard J., and Nielsen J. Mass Spectrom. Rev. 24 (2005) 613-646
15. Smith C.A., Want E.J., O'Maille G., Abagyan R., and Siuzdak G. Anal. Chem. 78 (2006) 779-787
16. Trygg J., Holmes E., and Lundstedt T. J. Proteome Res. 6 (2007) 469-479
17. Lavine B.K. Clustering and classification of analytical data. In: Meyers R.A. (Ed). Encyclopedia of Analytical Chemistry: Applications, Theory, and Instrumentation (2000), Wiley & Sons, New York 1-20
18. Plumb R.S., Stumpf C.L., Granger J.H., Castro-Perez J., Haselden J.N., and Dear G.J. Rapid Commun. Mass Spectrom. 17 (2003) 2632-2638
19. Idborg-Bjorkman H., Edlund P.O., Kvalheim O.M., Schuppe-Koistinen I., and Jacobsson S.P. Anal. Chem. 75 (2003) 4784-4792
20. Stolt R., Torgrip R.J.O., Lindberg J., Csenki L., Kolmert J., Schuppe-Koistinen I., and Jacobsson S.P. Anal. Chem. 78 (2006) 975-983
21. Aberg K.M., Torgrip R.J.O., Kolmert J., Schuppe-Koistinen I., and Lindberg J. J. Chromatogr. A 1192 (2008) 139-146
22. Sturm M., Bertsch A., Gropl C., Hildebrandt A., Hussong R., Lange E., Pfeifer N., Schulz-Trieglaff O., Zerck A., Reinert K., and Kohlbacher O. BMC Bioinform. 9 (2008) 163-173
23. Reichenbach H., and Dworkin M. The Myxobacteria. In: Balows A., Trüper H.G., Dworkin M., Harder W., and Schleifer K.H. (Eds). The Procaryotes (1992), Springer-Verlag, New York 3416-3487
24. Krug D., Zurek G., Revermann O., Vos M., Velicer G.J., and Müller R. Appl. Environ. Microbiol. 74 (2008) 3058-3068
25. Simunovic V., Zapp J., Rachid S., Krug D., Meiser P., and Müller R. ChemBioChem 7 (2006) 1206-1220
26. Ojanperä S., Pelander A., Pelzing M., Krebs I., Vuori E., and Ojanperä I. Rapid Commun. Mass Spectrom. 20 (2006) 1161-1167
27. Want E.J., Cravatt B.F., and Siuzdak G. ChemBioChem 6 (2005) 1941-1951
28. D. Krug, G. Zurek, B. Schneider, C. Bässmann, R. Müller, in: A. Matheson (Ed.), The Applications Book March 2007, LC-GC Europe, Advanstar Communications, Chester, 2007, pp. 41-42.
29. Trowitzsch-Kienast W., Forche E., Wray V., Reichenbach H., Jurkiewicz E., Hunsmann G., and Höfle G. Liebigs Ann. Chem. 16 (1992) 659-664
30. Schneiker S., Perlova O., Kaiser O., Gerth K., Alici A., Altmeyer M.O., Bartels D., Bekel T., Beyer S., Bode E., Bode H.B., Bolten C.J., Choudhuri J.V., Doss S., Elnakady Y.A., Frank B., Gaigalat L., Goesmann A., Groeger C., Gross F., Jelsbak L., Jelsbak L., Kalinowski J., Kegler C., Knauber T., Konietzny S., Kopp M., Krause L., Krug D., Linke B., Mahmud T., Martinez-Arias R., McHardy A.C., Merai M., Meyer F., Mormann S., Munoz-Dorado J., Perez J., Pradella S., Rachid S., Raddatz G., Rosenau F., Ruckert C., Sasse F., Scharfe M., Schuster S.C., Suen G., Treuner-Lange A., Velicer G.J., Vorholter F.J., Weissman K.J., Welch R.D., Wenzel S.C., Whitworth D.E., Wilhelm S., Wittmann C., Blöcker H., Pühler A., and Müller R. Nat. Biotechnol. 25 (2007) 1281-1289
31. Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S., Eisen J., Ronning C.M., Barbazuk W.B., Blanchard M., Field C., Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R., Miller N., Shvartsbeyn A., Sullivan S.A., Vaudin M., Wiegand R., and Kaplan H.B. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 15200-15205
32. Schley C., Altmeyer M.O., Swart R., Müller R., and Huber C.G. J. Proteome Res. 5 (2006) 2760-2768