Ocular pharmacokinetic/pharmacodynamic modeling for multiple anti-glaucoma drugs

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 8, 2008, Pages 1590-1595

  Sakanaka, Koji ^a,b   Kawazu, Kouichi ^a   Tomonari, Masahide ^b   Kitahara, Takashi ^b   Nakashima, Mikiro ^c   Nishida, Koyo ^c   Nakamura, Junzo ^c   Sasaki, Hitoshi ^b   Higuchi, Shun ^d  

^a SANTEN PHARMACEUTICAL CO LTD   (Japan)

^b NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NAGASAKI UNIVERSITY   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

Aqueous humor dynamics; Bunazosin; Eye; Pharmacodynamics; Pharmacokinetics; Timolol

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ANTIGLAUCOMA AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BUNAZOSIN; TIMOLOL MALEATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS HUMOR FLOW; ARTICLE; CONTROLLED STUDY; DRUG DISPOSITION; DRUG EFFECT; DRUG ELIMINATION; DRUG INSTILLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; MALE; MATHEMATICAL MODEL; NONHUMAN; PHARMACODYNAMICS; RABBIT; TELEMETRY;

ADRENERGIC ALPHA-ANTAGONISTS; ADRENERGIC BETA-ANTAGONISTS; ALGORITHMS; ANIMALS; AQUEOUS HUMOR; DRUG COMBINATIONS; GLAUCOMA; INTRAOCULAR PRESSURE; MALE; MODELS, STATISTICAL; OCULAR HYPERTENSION; OPHTHALMIC SOLUTIONS; QUINAZOLINES; RABBITS; TELEMETRY; TIMOLOL;

EID: 48849115667     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.1590     Document Type: Article

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