The terminal sialic acid of glycoconjugates on the surface of intestinal epithelial cells activates excystation of Cryptosporidium parvum

Infection and Immunity

Volumn 76, Issue 8, 2008, Pages 3735-3741

  Choudhry, Naheed ^a   Bajaj Elliott, Mona ^b   McDonald, Vincent ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOCONJUGATE; LECTIN; SIALIC ACID; SIALIDASE; TRYPSIN; N ACETYLNEURAMINIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL ACTIVATION; CELL STRAIN; CELL STRAIN CACO 2; CMT93 CELL STRAIN; CRYPTOSPORIDIOSIS; CRYPTOSPORIDIUM PARVUM; DISEASE TRANSMISSION; HCT8 CELL STRAIN; INFESTATION; INTESTINE CELL; INTESTINE EPITHELIUM CELL; NONHUMAN; OOCYTE; PRIORITY JOURNAL; SPOROZOITE; ANIMAL; CELL LINE; CHEMISTRY; EPITHELIUM CELL; HUMAN; INTESTINE MUCOSA; METABOLISM; OOCYST; PARASITOLOGY; PHYSIOLOGY;

ANIMALS; CELL LINE; CRYPTOSPORIDIUM PARVUM; EPITHELIAL CELLS; GLYCOCONJUGATES; HUMANS; INTESTINAL MUCOSA; N-ACETYLNEURAMINIC ACID; OOCYSTS;

EID: 48849109895     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00362-08     Document Type: Article

References (26)

1. Achyuthan, K. E., and A. M. Achyuthan. 2001. Comparative enzymology, biochemistry, and pathophysiology of human exo-alpha-sialidases (neuraminidases). Comp. Biochem. Physiol. B Biochem. Mol. Biol. 129:29-64.
2. Amadi, B., M. Mwiya, J. Musuku, A. Watuka, S. Sianongo, A. Ayoub, and P. Kelly. 2002. Effect of nitazoxanide on morbidity and mortality in Zambian children with cryptosporidiosis: a randomised controlled trial. Lancet 360:1375-1380.
3. Barta, J. R., and R. C. Thompson. 2006. What is Cryptosporidium? Reappraising its biology and phylogenetic affinities. Trends Parasitol. 22:463-468.
4. Butler, M., C. Y. Ng, D. A. van Heel, G. Lombardi, R. Lechler, R. J. Playford, and S. Ghosh. 2006. Modulation of dendritic cell phenotype and function in an in vitro model of the intestinal epithelium. Eur. J. Immunol. 36:864-874.
5. Chava, A. K., S. Bandyopadhyay, M. Chatterjee, and C. Mandal. 2004. Sialoglycans in protozoal diseases: their detection, modes of acquisition and emerging biological roles. Glycoconj. J. 20:199-206.
6. Current, W. L., and N. C. Reese. 1986. A comparison of endogenous development of three isolates of Cryptosporidium in suckling mice. J. Protozool. 33:98-108.
7. Fayer, R., and R. G. Leek. 1984. The effects of reducing conditions, medium, pH, temperature, and time on in vitro excystation of Cryptosporidium. J. Protozool. 31:567-569.
8. Feng, H., W. Nie, A. Sheoran, Q. Zhang, and S. Tzipori. 2006. Bile acids enhance invasiveness of Cryptosporidium spp. into cultured cells. Infect. Immun. 74:3342-3346.
9. Forney, J. R., S. Yang, and M. C. Healey. 1996. Protease activity associated with excystation of Cryptosporidium parvum oocysts. J. Parasitol. 82:889-892.
10. Hamer, D. H., H. Ward, S. Tzipori, M. E. Pereira, J. P. Alroy, and G. T. Keusch. 1994. Attachment of Cryptosporidium parvum sporozoites to MDCK cells in vitro. Infect. Immun. 62:2208-2213.
11. Klotz, F. W., P. A. Orlandi, G. Reuter, S. J. Cohen, J. D. Haynes, R. Schauer, R. J. Howard, P. Palese, and L. H. Miller. 1992. Binding of Plasmodium falciparum 175-kilodalton erythrocyte binding antigen and invasion of murine erythrocytes requires N-acetylneuraminic acid but not its O-acetylated form. Mol. Biochem. Parasitol. 51:49-54.
12. Kovbasnjuk, O. N., and K. R. Spring. 2000. The apical membrane glycocalyx of MDCK cells. J. Membr. Biol. 176:19-29.
13. Li, Y., X. Yang, A. H. Nguyen, and I. Brockhausen. 2007. Requirement of N-glycosylation for the secretion of recombinant extracellular domain of human Fas in HeLa cells. Int. J. Biochem. Cell. Biol. 39:1625-1636.
14. Morgan-Ryan, U. M., A. Fall, L. A. Ward, N. Hijjawi, I. Sulaiman, R. Fayer, R. C. Thompson, M. Olson, A. Lal, and L. Xiao. 2002. Cryptosporidium hominis n. sp. (Apicomplexa: Cryptosporidiidae) from Homo sapiens. J. Eukaryot. Microbiol. 49:433-440.
15. Nanduri, J., S. Williams, T. Aji, and T. P. Flanigan. 1999. Characterization of an immunogenic glycocalyx on the surfaces of Cryptosporidium parvum oocysts and sporozoites. Infect. Immun. 67:2022-2024.
16. O'Donoghue, P. J. 1985. Cryptosporidium infections in man, animals, birds and fish. Aust. Vet. J. 62:253-258.
17. Robertson, L. J., A. T. Campbell, and H. V. Smith. 1993. In vitro excystation of Cryptosporidium parvum. Parasitology 106:13-19.
18. Schauer, R. 1982. Sialic acids: chemistry, metabolism, and function, p. 7-67. In R. Schauer (ed.), Cell biology monographs, vol. 10. Springer-Verlag, New York, NY.
19. Severi, E., D. W. Hood, and G. H. Thomas. 2007. Sialic acid utilization by bacterial pathogens. Microbiology 153:2817-2822.
20. Smith, H. V., R. A. Nichols, and A. M. Grimason. 2005. Cryptosporidium excystation and invasion: getting to the guts of the matter. Trends Parasitol. 21:133-142.
21. Stein, B., L. Stover, A. Gillem, K. Winters, J. H. Leet, and C. Chauret. 2006. The effect of lectins on Cryptosporidium parvum oocyst in vitro attachment to host cells. J. Parasitol. 92:1-9.
22. Tzipori, S., and H. Ward. 2002. Cryptosporidiosis: biology, pathogenesis, and disease. Microbes Infect. 4:1047-1058.
23. Ulloa, F., and F. X. Real. 2001. Differential distribution of sialic acid in α2,3 and α2,6 linkages in the apical membrane of cultured epithelial cells and tissues. J. Histochem. Cytochem. 49:501-510.
24. Ward, H., N. Bhat, and R. O'Connora. 2004. Structural physiology of the Cryptosporidium oocyst wall. American Water Works Association Research Foundation, Denver, CO.
25. Weir, S. C., N. J. Pokorny, R. A. Carreno, J. T. Trevors, and H. Lee. 2001. Improving the rate of infectivity of Cryptosporidium parvum oocysts in cell culture using centrifugation. J. Parasitol. 87:1502-1504.
26. 1H NMR investigation of sialic acid transfer by the trans-sialidase from Trypanosoma cruzi. Bioorg. Med. Chem. Lett. 10:2791-2794.