Vezf1: A transcriptional regulator of the endothelium

Endothelial Biomedicine

Volumn , Issue , 2007, Pages 855-860

  Kuhnert, Frank ^a   Stuhlmann, Heidi ^b  

^a Department of Cell and Developmental Weill Medical College of Cornell University ^*

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 48749122093     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1017/CBO9780511546198.096     Document Type: Chapter

References (17)

1. Kuhnert F, Stuhlmann H. Identifying early vascular genes through gene trapping in mouse embryonic stem cells. Curr Top Dev Biol. 2004; 62:261–281.
2. Leahy A, Xiong J-W, Kuhnert F, Stuhlmann H. Use of developmental marker genes to define temporal and spatial patterns of differentiation during embryoid body formation. J Exp Zool. 1999; 284:67–81.
3. Xiong J-W, Battaglino R, Leahy A, Stuhlmann H. Large-scale screening for developmental genes in ES cells and embryoid bodies using retroviral entrapment vectors. Dev Dyn. 1998; 212(2): 181–197.
4. Xiong J-W, Leahy A, Lee H-H, Stuhlmann H. Vezf1: a Zn finger transcription factor restricted to endothelial cells and their precursors. Dev Biol. 1999; 206:123–141.
5. Hackney JA, Charbord P, Brunk BP, et al. A molecular profile of a hematopoietic stem cell niche. Proc Natl Acad Sci USA. 2002; 99(20):13061–13066.
6. Koyano-Nakagawa N, Nishida J, Baldwin D, et al. Molecular cloning of a novel human cDNA encoding a zinc finger protein that binds to the interleukin-3 promoter.Mol Cell Biol. 1994; 14: 5099–5107.
7. Lapteva N, Ando Y, Nieda M, et al. Profiling of genes expressed in human monocytes and monocyte-derived dendritic cells using cDNA expression array. Br J Haematol. 2001; 114(1):191–197.
8. Kennedy GC, Rutter WJ. Pur-1, a zinc finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells. Proc Natl Acad Sci USA. 1992; 89:11498– 11502.
9. Song J, Murakami H, Tsutsui H, et al. Structural organization and expression of the mouse gene for Pur-1, a highly conserved homolog of the human MAZ gene. Eur J Biochem. 1999; 259(3): 676–683.
10. Bossone SA, Asselin C, Patel AJ, Marcu KB. MAZ, a zinc finger, binds to c-myc and C2 gene sequences regulating transcriptional initiation and termination. Proc Natl Acad Sci USA. 1992; 89: 7452–7456.
11. Duncan DD, Stupakoff A, Hedrick SM, et al. A myc-associated zinc finger protein binding site is one of four important functional regions in the CD4 promoter. Mol Cell Biol. 1995; 15(6): 3179–3186.
12. Aitsebaomo J, Wennerberg K, Der CJ, et al. p68RacGAP is a novel GTPase-activating protein that interacts with vascular endothelial zinc finger-1 and modulates endothelial cell capillary formation. J Biol Chem. 2004; 279(17):17963–17972.
13. Lebowitz PF, Prendergast GC. Functional interaction between RhoB and the transcription factor DB1. Cell Adhes Commun. 1998; 6(4):277–287.
14. Aitsebaomo J, Kingsley-Kallesen ML, Wu Y, et al. Vezf1/DB1 is an endothelial cell-specific transcription factor that regulates expression of the endothelin-1 promoter. J Biol Chem. 2001; 14:14.
15. Miyashita H, Kanemura M, Yamazaki T, et al. Vascular endothelial zinc finger 1 is involved in the regulation of angiogenesis: possible contribution of stathmin/OP18 as a downstream target gene. Arterioscler Thromb Vasc Biol. 2004; 24(5):878–884.
16. Kuhnert F, Campagnolo L, Xiong J-W, et al. Dosage-dependent requirement for mouse Vezf1 in vascular system development. Dev Biol. 2005; 283:140–156.
17. Adini I, Rabinovitz I, Sun JF, et al. RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development. Genes Dev. 2003; 17(21):2721–2732.