메뉴 건너뛰기




Volumn 33, Issue 2, 2008, Pages 253-259

VEGF blockade decelerates the growth of a murine experimental osteosarcoma

Author keywords

Gene transfer; Mouse model; Osteosarcoma; sFlt 1; VEGF blockage

Indexed keywords

BETA GALACTOSIDASE; MYC PROTEIN; PROTEIN C FOS; RETROVIRUS VECTOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1;

EID: 48749121296     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo_00000004     Document Type: Article
Times cited : (26)

References (40)
  • 1
    • 0015951422 scopus 로고
    • High-dose methotrexate with citrovorum factor rescue and adriamycin in childhood osteogenic sarcoma
    • Rosen G, Suwansirikul S, Kwon C, Tan C, Wu SJ, Beattie EJ Jr and Murphy ML: High-dose methotrexate with citrovorum factor rescue and adriamycin in childhood osteogenic sarcoma. Cancer 33: 1151-1163, 1974.
    • (1974) Cancer , vol.33 , pp. 1151-1163
    • Rosen, G.1    Suwansirikul, S.2    Kwon, C.3    Tan, C.4    Wu, S.J.5    Beattie Jr, E.J.6    Murphy, M.L.7
  • 2
    • 0032829104 scopus 로고    scopus 로고
    • Tumor angiogenesis-new drugs on the block
    • Brower V: Tumor angiogenesis-new drugs on the block. Nat Biotechnol 17: 963-968, 1999.
    • (1999) Nat Biotechnol , vol.17 , pp. 963-968
    • Brower, V.1
  • 3
    • 0032502843 scopus 로고    scopus 로고
    • Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor
    • Kong HL, Hecht D, Song W, Kovesdi I, Hackett NR, Yayon A and Crystal RG: Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor. Hum Gene Ther 9: 823-833, 1998.
    • (1998) Hum Gene Ther , vol.9 , pp. 823-833
    • Kong, H.L.1    Hecht, D.2    Song, W.3    Kovesdi, I.4    Hackett, N.R.5    Yayon, A.6    Crystal, R.G.7
  • 4
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
    • Millauer B, Shawver LK, Plate KH, Risau W and Ullrich A: Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 367: 576-579, 1994.
    • (1994) Nature , vol.367 , pp. 576-579
    • Millauer, B.1    Shawver, L.K.2    Plate, K.H.3    Risau, W.4    Ullrich, A.5
  • 5
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O'Reilly MS, Holmgren L, Shing Y, et al: Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79: 315-328, 1994.
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.S.1    Holmgren, L.2    Shing, Y.3
  • 6
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    • O'Reilly MS, Boehm T, Shing Y, et al: Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 88: 277-285, 1997.
    • (1997) Cell , vol.88 , pp. 277-285
    • O'Reilly, M.S.1    Boehm, T.2    Shing, Y.3
  • 7
    • 0027174375 scopus 로고
    • Inhibitory effect of angiogenesis inhibitor TNP-470 on tumor growth and metastasis of human cell lines in vitro and in vivo
    • Yanase T, Tamura M, Fujita K, Kodama S and Tanaka K: Inhibitory effect of angiogenesis inhibitor TNP-470 on tumor growth and metastasis of human cell lines in vitro and in vivo. Cancer Res 53: 2566-2570, 1993.
    • (1993) Cancer Res , vol.53 , pp. 2566-2570
    • Yanase, T.1    Tamura, M.2    Fujita, K.3    Kodama, S.4    Tanaka, K.5
  • 9
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J: Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186, 1971.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 10
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman J: What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82: 4-6, 1990.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 11
    • 0026846928 scopus 로고
    • The role of angiogenesis in tumor growth
    • Folkman J: The role of angiogenesis in tumor growth. Semin Cancer Biol 3: 65-71, 1992.
    • (1992) Semin Cancer Biol , vol.3 , pp. 65-71
    • Folkman, J.1
  • 12
    • 0023157363 scopus 로고
    • Angiogenic factors
    • Folkman J and Klagsbrun M: Angiogenic factors. Science 235: 442-447, 1987.
    • (1987) Science , vol.235 , pp. 442-447
    • Folkman, J.1    Klagsbrun, M.2
  • 13
    • 0027197245 scopus 로고
    • Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    • Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS and Ferrara N: Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362: 841-844, 1993.
    • (1993) Nature , vol.362 , pp. 841-844
    • Kim, K.J.1    Li, B.2    Winer, J.3    Armanini, M.4    Gillett, N.5    Phillips, H.S.6    Ferrara, N.7
  • 14
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung DW, Cachianes G, Kuang WJ, Goeddel DV and Ferrara N: Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246: 1306-1309, 1989.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 15
    • 0033166894 scopus 로고    scopus 로고
    • Cell-retained isoforms of vascular endothelial growth factor (VEGF) are correlated with poor prognosis in osteosarcoma
    • Lee YH, Tokunaga T, Oshika Y, et al: Cell-retained isoforms of vascular endothelial growth factor (VEGF) are correlated with poor prognosis in osteosarcoma. Eur J Cancer 35: 1089-1093, 1999.
    • (1999) Eur J Cancer , vol.35 , pp. 1089-1093
    • Lee, Y.H.1    Tokunaga, T.2    Oshika, Y.3
  • 16
    • 18844467502 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression in untreated osteosarcoma is predictive of pulmonary metastasis and poor prognosis
    • Kaya M, Wada T, Akatsuka T, et al: Vascular endothelial growth factor expression in untreated osteosarcoma is predictive of pulmonary metastasis and poor prognosis. Clin Cancer Res 6: 572-577, 2000.
    • (2000) Clin Cancer Res , vol.6 , pp. 572-577
    • Kaya, M.1    Wada, T.2    Akatsuka, T.3
  • 17
    • 36949011202 scopus 로고    scopus 로고
    • Yang SY, Yu HY, Jeffrey E, et al: High VEGF with rapid growth and early metastasis in a mouse osteosarcoma model. Sarcoma 2007: 95628 (7 pages), 2007.
    • Yang SY, Yu HY, Jeffrey E, et al: High VEGF with rapid growth and early metastasis in a mouse osteosarcoma model. Sarcoma 2007: 95628 (7 pages), 2007.
  • 18
    • 0027421333 scopus 로고
    • Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
    • Kendall RL and Thomas KA: Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci USA 90: 10705-10709, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10705-10709
    • Kendall, R.L.1    Thomas, K.A.2
  • 19
    • 0030582384 scopus 로고    scopus 로고
    • Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR
    • Kendall RL, Wang G and Thomas KA: Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochem Biophys Res Commun 226: 324-328, 1996.
    • (1996) Biochem Biophys Res Commun , vol.226 , pp. 324-328
    • Kendall, R.L.1    Wang, G.2    Thomas, K.A.3
  • 20
    • 0034655246 scopus 로고    scopus 로고
    • Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ
    • Takayama K, Ueno H, Nakanishi Y, et al: Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ. Cancer Res 60: 2169-2177, 2000.
    • (2000) Cancer Res , vol.60 , pp. 2169-2177
    • Takayama, K.1    Ueno, H.2    Nakanishi, Y.3
  • 21
    • 2442446450 scopus 로고    scopus 로고
    • Suppression of lung metastasis of renal cell carcinoma by the intramuscular gene transfer of a soluble form of vascular endothelial growth factor receptor I
    • Yoshimura I, Mizuguchi Y, Miyajima A, Asano T, Tadakuma T and Hayakawa M: Suppression of lung metastasis of renal cell carcinoma by the intramuscular gene transfer of a soluble form of vascular endothelial growth factor receptor I. J Urol 171: 2467-2470, 2004.
    • (2004) J Urol , vol.171 , pp. 2467-2470
    • Yoshimura, I.1    Mizuguchi, Y.2    Miyajima, A.3    Asano, T.4    Tadakuma, T.5    Hayakawa, M.6
  • 22
    • 2442640516 scopus 로고    scopus 로고
    • Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer
    • Sako A, Kitayama J, Koyama H, Ueno H, Uchida H, Hamada H and Nagawa H: Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer. Cancer Res 64: 3624-3628, 2004.
    • (2004) Cancer Res , vol.64 , pp. 3624-3628
    • Sako, A.1    Kitayama, J.2    Koyama, H.3    Ueno, H.4    Uchida, H.5    Hamada, H.6    Nagawa, H.7
  • 23
    • 20144389101 scopus 로고    scopus 로고
    • Combined endostatin/ sFlt-1 antiangiogenic gene therapy is highly effective in a rat model of HCC
    • Graepler F, Verbeek B, Graeter T, et al: Combined endostatin/ sFlt-1 antiangiogenic gene therapy is highly effective in a rat model of HCC. Hepatology 41: 879-886, 2005.
    • (2005) Hepatology , vol.41 , pp. 879-886
    • Graepler, F.1    Verbeek, B.2    Graeter, T.3
  • 24
    • 20144386752 scopus 로고    scopus 로고
    • Transfer of the sFLT-1 gene in Morris hepatoma results in decreased growth and perfusion and induction of genes associated with stress response
    • Schmidt K, Hoffend J, Altmann A, et al: Transfer of the sFLT-1 gene in Morris hepatoma results in decreased growth and perfusion and induction of genes associated with stress response. Clin Cancer Res 11: 2132-2140, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 2132-2140
    • Schmidt, K.1    Hoffend, J.2    Altmann, A.3
  • 25
    • 0842334575 scopus 로고    scopus 로고
    • sFlt-1 gene therapy of follicular thyroid carcinoma
    • Ye C, Feng C, Wang S, et al: sFlt-1 gene therapy of follicular thyroid carcinoma. Endocrinology 145: 817-822, 2004.
    • (2004) Endocrinology , vol.145 , pp. 817-822
    • Ye, C.1    Feng, C.2    Wang, S.3
  • 26
    • 0034772251 scopus 로고    scopus 로고
    • Adenovirus-mediated soluble FLT-1 gene therapy for ovarian carcinoma
    • Mahasreshti PJ, Navarro JG, Kataram M, et al: Adenovirus-mediated soluble FLT-1 gene therapy for ovarian carcinoma. Clin Cancer Res 7: 2057-2066, 2001.
    • (2001) Clin Cancer Res , vol.7 , pp. 2057-2066
    • Mahasreshti, P.J.1    Navarro, J.G.2    Kataram, M.3
  • 27
    • 0036738338 scopus 로고    scopus 로고
    • Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4
    • Peng H, Wright V, Usas A, Gearhart B, Shen HC, Cummins J and Huard J: Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4. J Clin Invest 110: 751-759, 2002.
    • (2002) J Clin Invest , vol.110 , pp. 751-759
    • Peng, H.1    Wright, V.2    Usas, A.3    Gearhart, B.4    Shen, H.C.5    Cummins, J.6    Huard, J.7
  • 28
    • 0036019456 scopus 로고    scopus 로고
    • IL-1Ra and vIL-10 gene transfer using retroviral vectors ameliorates particle-associated inflammation in the murine air pouch model
    • Yang S, Wu B, Mayton L, Evans CH, Robbins PD and Wooley PH: IL-1Ra and vIL-10 gene transfer using retroviral vectors ameliorates particle-associated inflammation in the murine air pouch model. Inflamm Res 51: 342-350, 2002.
    • (2002) Inflamm Res , vol.51 , pp. 342-350
    • Yang, S.1    Wu, B.2    Mayton, L.3    Evans, C.H.4    Robbins, P.D.5    Wooley, P.H.6
  • 29
    • 0035206031 scopus 로고    scopus 로고
    • Effects of cytokine gene therapy on particulate-induced inflammation in the murine air pouch
    • Sud S, Yang SY, Evans CH, Robbins PD and Wooley PH: Effects of cytokine gene therapy on particulate-induced inflammation in the murine air pouch. Inflammation 25: 361-372, 2001.
    • (2001) Inflammation , vol.25 , pp. 361-372
    • Sud, S.1    Yang, S.Y.2    Evans, C.H.3    Robbins, P.D.4    Wooley, P.H.5
  • 30
    • 0013939863 scopus 로고
    • Immunology of spontaneous mammary carcinomas in mice. V. Acquired tumor resistance and enhancement in strain A mice infected with mammary tumor virus
    • Attia MA and Weiss DW: Immunology of spontaneous mammary carcinomas in mice. V. Acquired tumor resistance and enhancement in strain A mice infected with mammary tumor virus. Cancer Res 26: 1787-1800, 1966.
    • (1966) Cancer Res , vol.26 , pp. 1787-1800
    • Attia, M.A.1    Weiss, D.W.2
  • 31
    • 1542329568 scopus 로고    scopus 로고
    • Protective effects of IL-1Ra or vIL-10 gene transfer on a murine model of wear debris-induced osteolysis
    • Yang SY, Wu B, Mayton L, Mukherjee P, Robbins PD, Evans CH and Wooley PH: Protective effects of IL-1Ra or vIL-10 gene transfer on a murine model of wear debris-induced osteolysis. Gene Ther 11: 483-491, 2004.
    • (2004) Gene Ther , vol.11 , pp. 483-491
    • Yang, S.Y.1    Wu, B.2    Mayton, L.3    Mukherjee, P.4    Robbins, P.D.5    Evans, C.H.6    Wooley, P.H.7
  • 32
    • 48749092300 scopus 로고    scopus 로고
    • PE Applied Biosystems: TagMan Cytokine Gene Expression Plate I; Protocol. Anonymous. P/N 4304671, 37-53, 1998.
    • PE Applied Biosystems: TagMan Cytokine Gene Expression Plate I; Protocol. Anonymous. P/N 4304671, 37-53, 1998.
  • 33
    • 0032868528 scopus 로고    scopus 로고
    • Hormone-refractory prostate cancer cells express functional follicle-stimulating hormone receptor (FSHR)
    • Ben-Josef E, Yang SY, Ji TH, et al: Hormone-refractory prostate cancer cells express functional follicle-stimulating hormone receptor (FSHR). J Urol 161: 970-976, 1999.
    • (1999) J Urol , vol.161 , pp. 970-976
    • Ben-Josef, E.1    Yang, S.Y.2    Ji, T.H.3
  • 34
    • 12444274779 scopus 로고    scopus 로고
    • Intravenous delivery of adenovirus-mediated soluble FLT-1 results in liver toxicity
    • Mahasreshti PJ, Kataram M, Wang MH, et al: Intravenous delivery of adenovirus-mediated soluble FLT-1 results in liver toxicity. Clin Cancer Res 9: 2701-2710, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 2701-2710
    • Mahasreshti, P.J.1    Kataram, M.2    Wang, M.H.3
  • 35
    • 0027624479 scopus 로고
    • Amplification of c-myc oncogene and absence of c-Ha-ras point mutation in human bone sarcoma
    • Barrios C, Castresana JS, Ruiz J and Kreicbergs A: Amplification of c-myc oncogene and absence of c-Ha-ras point mutation in human bone sarcoma. J Orthop Res 11: 556-563, 1993.
    • (1993) J Orthop Res , vol.11 , pp. 556-563
    • Barrios, C.1    Castresana, J.S.2    Ruiz, J.3    Kreicbergs, A.4
  • 36
    • 0031783711 scopus 로고    scopus 로고
    • C-myc and c-fos in human osteosarcoma: Prognostic value of mRNA and protein expression
    • Gamberi G, Benassi MS, Bohling T, et al: C-myc and c-fos in human osteosarcoma: prognostic value of mRNA and protein expression. Oncology 55: 556-563, 1998.
    • (1998) Oncology , vol.55 , pp. 556-563
    • Gamberi, G.1    Benassi, M.S.2    Bohling, T.3
  • 37
    • 0029782691 scopus 로고    scopus 로고
    • Oncogene alterations in primary, recurrent, and metastatic human bone tumors
    • Pompetti F, Rizzo P, Simon RM, et al: Oncogene alterations in primary, recurrent, and metastatic human bone tumors. J Cell Biochem 63: 37-50, 1996.
    • (1996) J Cell Biochem , vol.63 , pp. 37-50
    • Pompetti, F.1    Rizzo, P.2    Simon, R.M.3
  • 38
    • 0027241223 scopus 로고
    • Over-expression of c-fos increases recombination frequency in human osteosarcoma cells
    • Van den BS, Rahmsdorf HJ, Herrlich P and Kaina B: Over-expression of c-fos increases recombination frequency in human osteosarcoma cells. Carcinogenesis 14: 925-928, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 925-928
    • Van den, B.S.1    Rahmsdorf, H.J.2    Herrlich, P.3    Kaina, B.4
  • 40
    • 0033551390 scopus 로고    scopus 로고
    • The Myc oncoprotein: A critical evaluation of transactivation and target gene regulation
    • Cole MD and McMahon SB: The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation. Oncogene 18: 2916-2924, 1999.
    • (1999) Oncogene , vol.18 , pp. 2916-2924
    • Cole, M.D.1    McMahon, S.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.