The geodiamolide H, derived from Brazilian sponge Geodia corticostylifera, regulates actin cytoskeleton, migration and invasion of breast cancer cells cultured in three-dimensional environment

Journal of Cellular Physiology

Volumn 216, Issue 3, 2008, Pages 583-594

  Freitas, Vanessa M ^a   Rangel, Marisa ^b   Bisson, Letícia F ^a   Jaeger, Ruy G ^a   Machado Santelli, Gláucia M ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR;

ARTICLE; BREAST CANCER; CANCER CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL INVASION; CELL MIGRATION; CELL STRAIN MCF 7; CELL STRUCTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSKELETON; HORMONE BLOOD LEVEL; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL;

ACTINS; ANIMALS; APOPTOSIS; BIOCOMPATIBLE MATERIALS; BREAST NEOPLASMS; CELL CULTURE TECHNIQUES; CELL LINE; CELL MOVEMENT; CELL POLARITY; CELL SHAPE; COLLAGEN; CYTOCHALASIN D; CYTOSKELETON; DEPSIPEPTIDES; DRUG COMBINATIONS; FEMALE; GEODIA; HUMANS; LAMININ; NEOPLASM INVASIVENESS; NUCLEIC ACID SYNTHESIS INHIBITORS; PROTEOGLYCANS; TUMOR CELLS, CULTURED;

ECHINOIDEA; GEODIA;

EID: 48749120487     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21432     Document Type: Article

References (36)

1. Barr FA, Short B. 2003. Golgins in the structure and dynamics of the Golgi apparatus. Curr Opin Cell Biol 15:405-413.
2. Bissell MJ, Radisky DC, Rizki A, Weaver VM, Petersen OW. 2002. The organizing principle: Microenvironmental influences in the normal and malignant breast. Differentiation 70:537-546.
3. Bubb MR, Senderowicz AM, Sausville EA, Duncan KL, Korn ED. 1994. Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin. J Biol Chem 269:14869-14871.
4. Bubb MR, Spector I, Beyer BB, Fosen KM. 2000. Effects of jasplakinolide on the kinetics of actin polymerization. An explanation for certain in vivo observations. J Biol Chem 275:5163-5170.
5. Debnath J, Brugge JS. 2005. Modelling glandular epithelial cancers in three-dimensional cultures. Nat Rev Cancer 5:675-688.
6. Debnath J, Muthuswamy SK, Brugge JS. 2003. Morphogenesis and oncogenesis of MCF 10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30:256-268.
7. Decaestecker C, Debeir O, Van Ham P, Kiss R. 2007. Can anti-migratory drugs be screened in vitro? A review of 2D and 3 D assays for the quantitative analysis of cell migration. Med Res Rev 27:149-176.
8. Entschladen F, Drell TLt, Lang K, Joseph J, Zaenker KS. 2004. Tumour-cell migration, invasion, and metastasis: Navigation by neurotransmitters. Lancet Oncol 5:254-258.
9. Flanagan MD, Lin S. 1980. Cytochalasins block actin filament elongation by binding to high affinity sites associated with F-actin. J Biol Chem 255:835-838.
10. Giganti A, Friederich E. 2003. The actin cytoskeleton as a therapeutic target: State of the art and future directions. Prog Cell Cycle Res 5:511-525.
11. Hayot C, Debeir O, Van Ham P, Van Damme M, Kiss R, Decaestecker C. 2006. Characterization of the activities of actin-affecting drugs on tumor cell migration. Toxicol Appl Pharmacol 211:30-40.
12. Kirschmann DA, Seftor EA, Fong SF, Nieva DR, Sullivan CM, Edwards EM, Sommer P, Csiszar K, Hendrix MJ. 2002. A molecular role for lysyl oxidase in breast cancer invasion. Cancer Res 62:4478-4483.
13. Kjer-Nielsen L, Teasdale RD, van Vliet C, Gleeson PA. 1999. A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins. Curr Biol 9:38S-388.
14. Kunz-Schughart LA. 1999. Multicellular tumor spheroids: Intermediates between monolayer culture and in vivo tumor. Cell Biol Int 23:157-161.
15. Lee H, Goetzl EJ, An S. 2000. Lysophosphatidic acid and sphingosine I-phosphate stimulate endothelial cell wound healing. Am J Physiol Cell Physiol 278:C612-C618.
16. Leers MP, Kolgen W, Bjorklund V, Bergman T, Tribbick G, Persson B, Bjorklund P, Ramaekers FC, Bjorklund B, Nap M, Jornvall H, Schutte B. 1999. Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis. J Pathol 187:S67-572.
17. Mareel M, Leroy A. 2003. Clinical, cellular, and molecular aspects of cancer invasion. Physiol Rev 83:337-376.
18. Mayer B, Klement G, Kaneko M, Man S, Jothy S, Rak J, Kerbel RS. 2001. Multicellular gastric cancer spheroids recapitulate growth pattern and differentiation phenotype of human gastric carcinomas. Gastroenterology 121:839-852.
19. McCawley LJ, Matrisian LM. 2000. Matrix metalloproteinases: Multifunctional contributors to tumor progression. Mol Med Today 6:149-156.
20. Morais Freitas V, Nogueira da Gama de Souza L, Cyreno Oliveira E, Furuse C, Cavalcanti de Araujo V, Gastaldoni Jaeger R. 2007. Malignancy-related 67 kDa laminin receptor in adenoid cystic carcinoma. Effect on migration and beta-catenin expression. Oral Oncol 43:987-998.
21. Rangel M, Konno K, Brunaldi K, Procopio J, De Freitas JC. 2005. Neurotoxic activity induced by a haemolytic substance in the extract of the marine sponge Geodia corticostylifera. Comp Biochem Physiol C Toxicol Pharmacol 141:207-215.
22. Rangel M, Prado MP, Konno K, Naoki H, Freitas JC, Machado-Santelli GM. 2006. Cytoskeleton alterations induced by Geodia corticostylifera depsipeptides in breast cancer cells. Peptides 27:2047-2057.
23. Rao J, Li N. 2004. Microfilament actin remodeling as a potential target for cancer drug development. Curr Cancer Drug Targets 4:345-354.
24. Reginato MJ, Muthuswamy SK. 2006. Illuminating the center: Mechanisms regulating lumen formation and maintenance in mammary morphogenesis. J Mammary Gland Biol Neoplasia 11:205-211.
25. Reginato MJ, Mills KR, Paulus JK, Lynch DK, Sgroi DC, Debnath J, Muthuswamy SK, Brugge JS. 2003. Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nat Cell Biol 5:733-740.
26. Schiemann S, Schwirzke M, Brunner N, Weidle UH. 1998. Molecular analysis of two mammary carcinoma cell lines at the transcriptional level as a model system for progression of breast cancer. Clin Exp Metastasis 16:129-139.
27. Sequeira SJ, Ranganathan AC, Adam AP, Iglesias BV, Farias EF, Aguirre-Ghiso JA. 2007. Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation. PLoS ONE 2:e615.
28. Short B, Haas A, Barr FA. 2005. Golgins and GTPases, giving identity and structure to the Golgi apparatus. Biochim Biophys Acta 1744:383-395.
29. Simone NL, Paweletz CP, Charboneau L, Petricoin EF III, Liotta LA. 2000. Laser capture microdissection: Beyond functional genomics to proteomics. Mol Diagn 5:301-307.
30. Stehn JR, Schevzov G, O'Neill GM, Gunning PW. 2006. Specialisation of the tropomyosin composition of actin filaments provides new potential targets for chemotherapy. Curr Cancer Drug Targets 6:245-256.
31. Wang F, Hansen RK, Radisky D, Yoneda T, Barcellos-Hoff MH, Petersen OW, Turley EA, Bissell MJ. 2002. Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts. J Natl Cancer Inst 94:1494-1503.
32. Weaver VM, Bissell MJ. 1999. Functional culture models to study mechanisms governing apoptosis in normal and malignant mammary epithelial cells. J Mammary Gland Biol Neoplasia 4:193-201.
33. Weaver VM, Petersen OW, Wang F, Larabell CA, Briand P, Damsky C, Bissell MJ. 1997. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 137:231-245.
34. Weiske J, Huber O. 2006. The histidine triad protein Hint1 triggers apoptosis independent of its enzymatic activity. J Biol Chem 281:27356-27366.
35. Yamaguchi H, Condeelis J. 2007. Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta 1773:642-652.
36. Zietarska M, Maugard CM, Filali-Mouhim A, Alam-Fahmy M, Tonin PN, Provencher DM, Mes-Masson AM. 2007. Molecular description of a 3D in vitro model for the study of epithelial ovarian cancer (EOC). Mol Carcinog 46:872-885.