Arsenic trioxide down-regulates antiapoptotic genes and induces cell death in mycosis fungoides tumors in a mouse model

Annals of Oncology

Volumn 19, Issue 8, 2008, Pages 1488-1494

  Tun Kyi, A ^a,c   Qin, J Z ^b   Oberholzer, P A ^a   Navarini, A A ^a   Hassel, J C ^a   Dummer, R ^a   Döbbeling, Udo ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cancer therapy; Cell death survival genes; Cutaneous T cell lymphoma; Gene regulation; Oncogenes; Transcription factors

Indexed keywords

7 AMINODACTINOMYCIN; APOPTOSIS REGULATORY PROTEIN; ARSENIC TRIOXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOCORTIN 5; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; STAT PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CUTANEOUS T CELL LYMPHOMA; DNA BINDING; DOSE RESPONSE; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; MOUSE; MYCOSIS FUNGOIDES; NONHUMAN; PRIORITY JOURNAL; TUMOR REGRESSION; WESTERN BLOTTING;

EID: 48749119783     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdn056     Document Type: Article

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