-
1
-
-
12944271053
-
Cancer statistics
-
Jemal A., Murray T., Ward E., Samuels A., Tiwari R.C., Ghafoor A., Feuer E.J., and Thun M.J. Cancer statistics. CA Cancer J. Clin. 55 (2005) 10-30
-
(2005)
CA Cancer J. Clin.
, vol.55
, pp. 10-30
-
-
Jemal, A.1
Murray, T.2
Ward, E.3
Samuels, A.4
Tiwari, R.C.5
Ghafoor, A.6
Feuer, E.J.7
Thun, M.J.8
-
2
-
-
0141503311
-
Changing constituents of genitourinary cancer in recent 50 years in Beijing
-
Gu F. Changing constituents of genitourinary cancer in recent 50 years in Beijing. Chin. Med. J. (Engl.) 116 (2003) 1391-1393
-
(2003)
Chin. Med. J. (Engl.)
, vol.116
, pp. 1391-1393
-
-
Gu, F.1
-
3
-
-
0034085989
-
Metastatic patterns of prostate cancer: an autopsy study of 1589 patients
-
Bubendorf L., Schöpfer A., Wagner U., Sauter G., Moch H., Willi N., Gasser T.C., and Mihatsch M.J. Metastatic patterns of prostate cancer: an autopsy study of 1589 patients. Hum. Pathol. 31 (2000) 578-583
-
(2000)
Hum. Pathol.
, vol.31
, pp. 578-583
-
-
Bubendorf, L.1
Schöpfer, A.2
Wagner, U.3
Sauter, G.4
Moch, H.5
Willi, N.6
Gasser, T.C.7
Mihatsch, M.J.8
-
4
-
-
4644261592
-
Mechanisms of bone metastasis
-
Roodman G.D. Mechanisms of bone metastasis. N. Engl. J. Med. 350 (2004) 1655-1664
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1655-1664
-
-
Roodman, G.D.1
-
5
-
-
0032851160
-
Functions of cell surface heparan sulfate proteoglycans
-
Bernfield M., Götte M., Park P.W., Reizes O., Fitzgerald M.L., Lincecum J., and Zako M. Functions of cell surface heparan sulfate proteoglycans. Annu. Rev. Biochem. 68 (1999) 729-777
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 729-777
-
-
Bernfield, M.1
Götte, M.2
Park, P.W.3
Reizes, O.4
Fitzgerald, M.L.5
Lincecum, J.6
Zako, M.7
-
6
-
-
0037162555
-
Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis
-
Goldshmidt O., Zcharia E., Abramovitch R., Metzger S., Aingorn H., Friedmann Y., Schirrmacher V., Mitrani E., and Vlodavsky I. Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis. Proc. Natl. Acad. Sci. USA 99 (2002) 10031-10036
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10031-10036
-
-
Goldshmidt, O.1
Zcharia, E.2
Abramovitch, R.3
Metzger, S.4
Aingorn, H.5
Friedmann, Y.6
Schirrmacher, V.7
Mitrani, E.8
Vlodavsky, I.9
-
7
-
-
4344598247
-
Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis
-
Edovitsky E., Elkin M., Zcharia E., Peretz T., and Vlodavsky I. Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis. J. Natl. Cancer Inst. 96 (2004) 1219-1230
-
(2004)
J. Natl. Cancer Inst.
, vol.96
, pp. 1219-1230
-
-
Edovitsky, E.1
Elkin, M.2
Zcharia, E.3
Peretz, T.4
Vlodavsky, I.5
-
8
-
-
33644863802
-
Heparanase promotes growth, angiogenesis and survival of primary breast tumors
-
Cohen I., Pappo O., Elkin M., San T., Bar-Shavit R., Hazan R., Peretz T., Vlodavsky I., and Abramovitch R. Heparanase promotes growth, angiogenesis and survival of primary breast tumors. Int. J. Cancer 118 (2006) 1609-1617
-
(2006)
Int. J. Cancer
, vol.118
, pp. 1609-1617
-
-
Cohen, I.1
Pappo, O.2
Elkin, M.3
San, T.4
Bar-Shavit, R.5
Hazan, R.6
Peretz, T.7
Vlodavsky, I.8
Abramovitch, R.9
-
9
-
-
9144268931
-
High heparanase activity in multiple myeloma is associated with elevated microvessel density
-
Kelly T., Miao H.Q., Yang Y., Navarro E., Kussie P., Huang Y., MacLeod V., Casciano J., Joseph L., Zhan F., Zangari M., Barlogie B., Shaughnessy J., and Sanderson R.D. High heparanase activity in multiple myeloma is associated with elevated microvessel density. Cancer Res. 63 (2003) 8749-8756
-
(2003)
Cancer Res.
, vol.63
, pp. 8749-8756
-
-
Kelly, T.1
Miao, H.Q.2
Yang, Y.3
Navarro, E.4
Kussie, P.5
Huang, Y.6
MacLeod, V.7
Casciano, J.8
Joseph, L.9
Zhan, F.10
Zangari, M.11
Barlogie, B.12
Shaughnessy, J.13
Sanderson, R.D.14
-
10
-
-
0035875082
-
Heparanase expression in primary and metastatic pancreatic cancer
-
Koliopanos A., Friess H., Kleeff J., Shi X., Liao Q., Pecker I., Vlodavsky I., Zimmermann A., and Büchler M.W. Heparanase expression in primary and metastatic pancreatic cancer. Cancer Res. 61 (2001) 4655-4659
-
(2001)
Cancer Res.
, vol.61
, pp. 4655-4659
-
-
Koliopanos, A.1
Friess, H.2
Kleeff, J.3
Shi, X.4
Liao, Q.5
Pecker, I.6
Vlodavsky, I.7
Zimmermann, A.8
Büchler, M.W.9
-
11
-
-
0034827642
-
Heparanase protein and gene expression in bladder cancer
-
Gohji K., Okamoto M., Kitazawa S., Toyoshima M., Dong J., Katsuoka Y., and Nakajima M. Heparanase protein and gene expression in bladder cancer. J. Urol. 166 (2001) 1286-1290
-
(2001)
J. Urol.
, vol.166
, pp. 1286-1290
-
-
Gohji, K.1
Okamoto, M.2
Kitazawa, S.3
Toyoshima, M.4
Dong, J.5
Katsuoka, Y.6
Nakajima, M.7
-
12
-
-
0142060014
-
Heparanase-1 gene expression in normal, hyperplastic and neoplastic prostatic tissue
-
Stadlmann S., Moser P.L., Pollheimer J., Steiner P., Krugmann J., Dirnhofer S., Mikuz G., Margreiter R., and Amberger A. Heparanase-1 gene expression in normal, hyperplastic and neoplastic prostatic tissue. Eur. J. Cancer 39 (2003) 2229-2233
-
(2003)
Eur. J. Cancer
, vol.39
, pp. 2229-2233
-
-
Stadlmann, S.1
Moser, P.L.2
Pollheimer, J.3
Steiner, P.4
Krugmann, J.5
Dirnhofer, S.6
Mikuz, G.7
Margreiter, R.8
Amberger, A.9
-
13
-
-
7944230119
-
Heparan sulfate proteoglycans and heparanase-partners in osteolytic tumor growth and metastasis
-
Sanderson R.D., Yang Y., Suva L.J., and Kelly T. Heparan sulfate proteoglycans and heparanase-partners in osteolytic tumor growth and metastasis. Matrix Biol. 23 (2004) 341-352
-
(2004)
Matrix Biol.
, vol.23
, pp. 341-352
-
-
Sanderson, R.D.1
Yang, Y.2
Suva, L.J.3
Kelly, T.4
-
14
-
-
21344452789
-
Expression of heparanase by primary breast tumors promotes bone resorption in the absence of detectable bone metastases
-
Kelly T., Suva L.J., Huang Y., Macleod V., Miao H.Q., Walker R.C., and Sanderson R.D. Expression of heparanase by primary breast tumors promotes bone resorption in the absence of detectable bone metastases. Cancer Res. 65 (2005) 5778-5784
-
(2005)
Cancer Res.
, vol.65
, pp. 5778-5784
-
-
Kelly, T.1
Suva, L.J.2
Huang, Y.3
Macleod, V.4
Miao, H.Q.5
Walker, R.C.6
Sanderson, R.D.7
-
15
-
-
29744433264
-
Synthesis, biological activity, and preliminary pharmacokinetic evaluation of analogues of a phosphosulfomannan angiogenesis inhibitor (PI-88)
-
Karoli T., Liu L., Fairweather J.K., Hammond E., Li C.P., Cochran S., Bergefall K., Trybala E., Addison R.S., and Ferro V. Synthesis, biological activity, and preliminary pharmacokinetic evaluation of analogues of a phosphosulfomannan angiogenesis inhibitor (PI-88). J. Med. Chem. 48 (2005) 8229-8236
-
(2005)
J. Med. Chem.
, vol.48
, pp. 8229-8236
-
-
Karoli, T.1
Liu, L.2
Fairweather, J.K.3
Hammond, E.4
Li, C.P.5
Cochran, S.6
Bergefall, K.7
Trybala, E.8
Addison, R.S.9
Ferro, V.10
-
16
-
-
4143140258
-
Structure-based design of a selective heparanase inhibitor as an antimetastatic agent
-
Ishida K., Hirai G., Murakami K., Teruya T., Simizu S., Sodeoka M., and Osada H. Structure-based design of a selective heparanase inhibitor as an antimetastatic agent. Mol. Cancer Ther. 3 (2004) 1069-1077
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 1069-1077
-
-
Ishida, K.1
Hirai, G.2
Murakami, K.3
Teruya, T.4
Simizu, S.5
Sodeoka, M.6
Osada, H.7
-
17
-
-
0037457306
-
Inhibition of heparanase activity and heparanase-induced angiogenesis by suramin analogues
-
Marchetti D., Reiland J., Erwin B., and Roy M. Inhibition of heparanase activity and heparanase-induced angiogenesis by suramin analogues. Int. J. Cancer 104 (2003) 167-174
-
(2003)
Int. J. Cancer
, vol.104
, pp. 167-174
-
-
Marchetti, D.1
Reiland, J.2
Erwin, B.3
Roy, M.4
-
18
-
-
20444394457
-
A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer
-
Joyce J.A., Freeman C., Meyer-Morse N., Parish C.R., and Hanahan D. A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer. Oncogene 24 (2005) 4037-4051
-
(2005)
Oncogene
, vol.24
, pp. 4037-4051
-
-
Joyce, J.A.1
Freeman, C.2
Meyer-Morse, N.3
Parish, C.R.4
Hanahan, D.5
-
19
-
-
33749347624
-
A phase I biological and pharmacologic study of the heparanase inhibitor PI-88 in patients with advanced solid tumors
-
Basche M., Gustafson D.L., Holden S.N., O'Bryant C.L., Gore L., Witta S., Schultz M.K., Morrow M., Levin A., Creese B.R., Kangas M., Roberts K., Nguyen T., Davis K., Addison R.S., Moore J.C., and Eckhardt S.G. A phase I biological and pharmacologic study of the heparanase inhibitor PI-88 in patients with advanced solid tumors. Clin. Cancer Res. 12 (2006) 5471-5480
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 5471-5480
-
-
Basche, M.1
Gustafson, D.L.2
Holden, S.N.3
O'Bryant, C.L.4
Gore, L.5
Witta, S.6
Schultz, M.K.7
Morrow, M.8
Levin, A.9
Creese, B.R.10
Kangas, M.11
Roberts, K.12
Nguyen, T.13
Davis, K.14
Addison, R.S.15
Moore, J.C.16
Eckhardt, S.G.17
-
20
-
-
19944430539
-
Heparanase promotes the spontaneous metastasis of myeloma cells to bone
-
Yang Y., Macleod V., Bendre M., Huang Y., Theus A.M., Miao H.Q., Kussie P., Yaccoby S., Epstein J., Suva L.J., Kelly T., and Sanderson R.D. Heparanase promotes the spontaneous metastasis of myeloma cells to bone. Blood 105 (2005) 1303-1309
-
(2005)
Blood
, vol.105
, pp. 1303-1309
-
-
Yang, Y.1
Macleod, V.2
Bendre, M.3
Huang, Y.4
Theus, A.M.5
Miao, H.Q.6
Kussie, P.7
Yaccoby, S.8
Epstein, J.9
Suva, L.J.10
Kelly, T.11
Sanderson, R.D.12
-
21
-
-
33646342005
-
Heparanase is expressed in osteoblastic cells and stimulates bone formation and bone mass
-
Kram V., Zcharia E., Yacoby-Zeevi O., Metzger S., Chajek-Shaul T., Gabet Y., Müller R., Vlodavsky I., and Bab I. Heparanase is expressed in osteoblastic cells and stimulates bone formation and bone mass. J. Cell Physiol. 207 (2006) 784-792
-
(2006)
J. Cell Physiol.
, vol.207
, pp. 784-792
-
-
Kram, V.1
Zcharia, E.2
Yacoby-Zeevi, O.3
Metzger, S.4
Chajek-Shaul, T.5
Gabet, Y.6
Müller, R.7
Vlodavsky, I.8
Bab, I.9
-
22
-
-
1642290776
-
Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype
-
Wang J., Xi L., Hunt J.L., Gooding W., Whiteside T.L., Chen Z., Godfrey T.E., and Ferris R.L. Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype. Cancer Res. 64 (2004) 1861-1866
-
(2004)
Cancer Res.
, vol.64
, pp. 1861-1866
-
-
Wang, J.1
Xi, L.2
Hunt, J.L.3
Gooding, W.4
Whiteside, T.L.5
Chen, Z.6
Godfrey, T.E.7
Ferris, R.L.8
-
23
-
-
27644501934
-
The effects of RANK blockade and osteoclast depletion in a model of pure osteoblastic prostate cancer metastasis in bone
-
Whang P.G., Schwarz E.M., Gamradt S.C., Dougall W.C., and Lieberman J.R. The effects of RANK blockade and osteoclast depletion in a model of pure osteoblastic prostate cancer metastasis in bone. J. Orthop. Res. 23 (2005) 1475-1483
-
(2005)
J. Orthop. Res.
, vol.23
, pp. 1475-1483
-
-
Whang, P.G.1
Schwarz, E.M.2
Gamradt, S.C.3
Dougall, W.C.4
Lieberman, J.R.5
-
24
-
-
33845214085
-
A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model
-
Ohno H., Kubo K., Murooka H., Kobayashi Y., Nishitoba T., Shibuya M., Yoneda T., and Isoe T. A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model. Mol. Cancer Ther. 5 (2006) 2634-2643
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 2634-2643
-
-
Ohno, H.1
Kubo, K.2
Murooka, H.3
Kobayashi, Y.4
Nishitoba, T.5
Shibuya, M.6
Yoneda, T.7
Isoe, T.8
-
25
-
-
0037156954
-
Heparanase expression is a prognostic indicator for postoperative survival in pancreatic adenocarcinoma
-
Rohloff J., Zinke J., Schoppmeyer K., Tannapfel A., Witzigmann H., Mössner J., Wittekind C., and Caca K. Heparanase expression is a prognostic indicator for postoperative survival in pancreatic adenocarcinoma. Br. J. Cancer 86 (2002) 1270-1275
-
(2002)
Br. J. Cancer
, vol.86
, pp. 1270-1275
-
-
Rohloff, J.1
Zinke, J.2
Schoppmeyer, K.3
Tannapfel, A.4
Witzigmann, H.5
Mössner, J.6
Wittekind, C.7
Caca, K.8
-
26
-
-
0037799669
-
Heparanase expression correlates with invasion and poor prognosis in gastric cancers
-
Takaoka M., Naomoto Y., Ohkawa T., Uetsuka H., Shirakawa Y., Uno F., Fujiwara T., Gunduz M., Nagatsuka H., Nakajima M., Tanaka N., and Haisa M. Heparanase expression correlates with invasion and poor prognosis in gastric cancers. Lab. Invest. 83 (2003) 613-622
-
(2003)
Lab. Invest.
, vol.83
, pp. 613-622
-
-
Takaoka, M.1
Naomoto, Y.2
Ohkawa, T.3
Uetsuka, H.4
Shirakawa, Y.5
Uno, F.6
Fujiwara, T.7
Gunduz, M.8
Nagatsuka, H.9
Nakajima, M.10
Tanaka, N.11
Haisa, M.12
-
27
-
-
0023037767
-
Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-sepharose
-
Hauschka P.V., Mavrakos A.E., Iafrati M.D., Doleman S.E., and Klagsbrun M. Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-sepharose. J. Biol. Chem. 261 (1986) 12665-12674
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 12665-12674
-
-
Hauschka, P.V.1
Mavrakos, A.E.2
Iafrati, M.D.3
Doleman, S.E.4
Klagsbrun, M.5
-
28
-
-
0036187204
-
Human prostatic carcinoma cells produce an increase in the synthesis of interleukin-6 by human osteoblasts
-
García-Moreno C., Méndez-Dávila C., de La Piedra C., Castro-Errecaborde N.A., and Traba M.L. Human prostatic carcinoma cells produce an increase in the synthesis of interleukin-6 by human osteoblasts. Prostate 50 (2002) 241-246
-
(2002)
Prostate
, vol.50
, pp. 241-246
-
-
García-Moreno, C.1
Méndez-Dávila, C.2
de La Piedra, C.3
Castro-Errecaborde, N.A.4
Traba, M.L.5
-
29
-
-
0034999898
-
Monitoring metastatic behavior of human tumor cells in mice with species-specific polymerase chain reaction: elevated expression of angiogenesis and bone resorption stimulators by breast cancer in bone metastases
-
van der Pluijm G., Sijmons B., Vloedgraven H., Deckers M., Papapoulos S., and Löwik C. Monitoring metastatic behavior of human tumor cells in mice with species-specific polymerase chain reaction: elevated expression of angiogenesis and bone resorption stimulators by breast cancer in bone metastases. J. Bone Miner. Res. 16 (2001) 1077-1091
-
(2001)
J. Bone Miner. Res.
, vol.16
, pp. 1077-1091
-
-
van der Pluijm, G.1
Sijmons, B.2
Vloedgraven, H.3
Deckers, M.4
Papapoulos, S.5
Löwik, C.6
-
30
-
-
28244481510
-
Vascular endothelial growth factor contributes to prostate cancer-mediated osteoblastic activity
-
Kitagawa Y., Dai J., Zhang J., Keller J.M., Nor J., Yao Z., and Keller E.T. Vascular endothelial growth factor contributes to prostate cancer-mediated osteoblastic activity. Cancer Res. 65 (2005) 10921-10929
-
(2005)
Cancer Res.
, vol.65
, pp. 10921-10929
-
-
Kitagawa, Y.1
Dai, J.2
Zhang, J.3
Keller, J.M.4
Nor, J.5
Yao, Z.6
Keller, E.T.7
-
31
-
-
33747890209
-
The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells
-
Sterling J.A., Oyajobi B.O., Grubbs B., Padalecki S.S., Munoz S.A., Gupta A., Story B., Zhao M., and Mundy G.R. The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells. Cancer Res. 66 (2006) 7548-7553
-
(2006)
Cancer Res.
, vol.66
, pp. 7548-7553
-
-
Sterling, J.A.1
Oyajobi, B.O.2
Grubbs, B.3
Padalecki, S.S.4
Munoz, S.A.5
Gupta, A.6
Story, B.7
Zhao, M.8
Mundy, G.R.9
-
32
-
-
33749473455
-
Extracellular calcium as a candidate mediator of prostate cancer skeletal metastasis
-
Liao J., Schneider A., Datta N.S., and McCauley L.K. Extracellular calcium as a candidate mediator of prostate cancer skeletal metastasis. Cancer Res. 66 (2006) 9065-9073
-
(2006)
Cancer Res.
, vol.66
, pp. 9065-9073
-
-
Liao, J.1
Schneider, A.2
Datta, N.S.3
McCauley, L.K.4
-
33
-
-
0036468926
-
Tumor-derived platelet-derived growth factor-BB plays a critical role in osteosclerotic bone metastasis in an animal model of human breast cancer
-
Yi B., Williams P.J., Niewolna M., Wang Y., and Yoneda T. Tumor-derived platelet-derived growth factor-BB plays a critical role in osteosclerotic bone metastasis in an animal model of human breast cancer. Cancer Res. 62 (2002) 917-923
-
(2002)
Cancer Res.
, vol.62
, pp. 917-923
-
-
Yi, B.1
Williams, P.J.2
Niewolna, M.3
Wang, Y.4
Yoneda, T.5
|