Live imaging of altered period1 expression in the suprachiasmatic nuclei of Vipr2-/- mice

Journal of Neurochemistry

Volumn 106, Issue 4, 2008, Pages 1646-1657

  Hughes, Alun T L ^a   Guilding, Clare ^a   Lennox, Laura ^a   Samuels, Rayna E ^a   McMahon, Douglas G ^b   Piggins, Hugh D ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

Circadian; Green fluorescent protein; Imaging; Period1; Suprachiasmatic nucleus; Vasoactive intestinal polypeptide

Indexed keywords

GREEN FLUORESCENT PROTEIN; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2; VASOPRESSIN;

AMPLITUDE MODULATION; ANIMAL TISSUE; ARTICLE; CELL COMMUNICATION; CELL COUNT; CELL SYNCHRONIZATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENOME; GENOTYPE; MALE; NONHUMAN; OSCILLATION; PER1 GENE; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR BLOCKING; SUPRACHIASMATIC NUCLEUS; WILD TYPE;

ANIMALS; CELLS, CULTURED; EYE PROTEINS; FEMALE; GENE EXPRESSION REGULATION; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; MOTOR ACTIVITY; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE, TYPE II; SUPRACHIASMATIC NUCLEUS;

MUS;

EID: 48749091779     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05520.x     Document Type: Article

References (42)

1. Abrahamson E. E. Moore R. Y. (2001) Suprachiasmatic nucleus in the mouse: retinal innervation, intrinsic organization and efferent projections. Brain Res. 916, 172 191.
2. Antle M. C. Silver R. (2005) Orchestrating time: arrangements of the brain circadian clock. Trends Neurosci. 28, 145 151.
3. Aton S. J., Colwell C. S., Harmar A. J., Waschek J. Herzog E. D. (2005) Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons. Nat. Neurosci. 8, 476 483.
4. Bechtold D. A., Brown T. M., Luckman S. M. Piggins H. D. (2008) Metabolic rhythm abnormalities in mice lacking VIP-VPAC2 signaling. Am. J. Physiol. Regul. Integr. Comp. Physiol. 294, R344 R351.
5. Brown T. M. Piggins H. D. (2007) Electrophysiology of the suprachiasmatic circadian clock. Prog. Neurobiol. 82, 229 255.
6. 2 receptor signaling. J. Neurosci. 25, 11155 11164.
7. Brown T. M., Colwell C. S., Waschek J. A. Piggins H. D. (2007) Disrupted neuronal activity rhythms in the suprachiasmatic nuclei of vasoactive intestinal polypeptide-deficient mice. J. Neurophysiol. 97, 2553 2558.
8. Colwell C. S., Michel S., Itri J., Rodriguez W., Tam J., Lelievre V., Hu Z., Liu X. Waschek J. A. (2003) Disrupted circadian rhythms in VIP- and PHI-deficient mice. Am. J. Physiol. Reg. I 285, R939 R949.
9. Cutler D. J., Haraura M., Reed H. E., Shen S., Sheward W. J., Morrison C. F., Marston H. M., Harmar A. J. Piggins H. D. (2003) The mouse VPAC(2) receptor confers suprachiasmatic nuclei cellular rhythmicity and responsiveness to vasoactive intestinal polypeptide in vitro. Eur. J. Neurosci. 17, 197 204.
10. Harmar A. J., Marston H. M., Shen S. B. et al. (2002) The VPAC(2) receptor is essential for circadian function in the mouse suprachiasmatic nuclei. Cell 109, 497 508.
11. Hastings M. H. Herzog E. D. (2004) Clock genes, oscillators, and cellular networks in the suprachiasmatic nuclei. J. Biol. Rhythms 19, 400 413.
12. Herzog E. D. (2007) Neurons and networks in daily rhythms. Nat. Rev. Neurosci. 8, 790 802.
13. Herzog E. D., Geusz M. E., Khalsa S. B., Straume M. Block G. D. (1997) Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates. Brain Res. 757, 285 290.
14. Hofman M. A. Swaab D. F. (2006) Living by the clock: the circadian pacemaker in older people. Ageing Res. Rev. 5, 33 51.
15. -/- Mice. J. Biol. Rhythms 23, 211 219.
16. Hughes A. T., Fahey B., Cutler D. J., Coogan A. N. Piggins H. D. (2004) Aberrant gating of photic input to the suprachiasmatic circadian pacemaker of mice lacking the VPAC(2) receptor. J. Neurosci. 24, 3522 3526.
17. Kalamatianos T., Kallo I., Piggins H. D. Coen C. W. (2004) Expression of VIP and/or PACAP receptor mRNA in peptide synthesizing cells within the suprachiasmatic nucleus of the rat and in its efferent target sites. J. Comp. Neurol. 475, 19 35.
18. Kallo I., Kalamatianos T., Wiltshire N., Shen S., Sheward W. J., Harmar A. J. Coen C. W. (2004) Transgenic approach reveals expression of the VPAC2 receptor in phenotypically defined neurons in the mouse suprachiasmatic nucleus and in its efferent target sites. Eur. J. Neurosci. 19, 2201 2211.
19. Ko C. H. Takahashi J. S. (2006) Molecular components of the mammalian circadian clock. Hum. Mol. Genet. 15 (Spec. No. 2 R271 R277.
20. Kuhlman S. J., Quintero J. E. McMahon D. G. (2000) GFP fluorescence reports PeriodI circadian gene regulation in the mammalian biological clock. Neuroreport 11, 1479 1482.
21. LeSauter J., Yan L., Vishnubhotla B., Quintero J. E., Kuhlman S. J., McMahon D. G. Silver R. (2003) A short half-life GFP mouse model for analysis of suprachiasmatic nucleus organization. Brain Res. 964, 279 287.
22. Liu C., Weaver D. R., Strogatz S. H. Reppert S. M. (1997) Cellular construction of a circadian clock: period determination in the suprachiasmatic nuclei. Cell 91, 855 860.
23. Liu A. C., Welsh D. K., Ko C. H. et al. (2007) Intercellular coupling confers robustness against mutations in the SCN circadian clock network. Cell 129, 605 616.
24. Maywood E. S., Reddy A. B., Wong G. K. Y., O'Neill J. S., O'Brien J. A., McMahon D. G., Harmar A. J., Okamura H. Hastings M. H. (2006) Synchronization and maintenance of timekeeping in suprachiasmatic circadian clock cells by neuropeptidergic signaling. Curr. Biol. 16, 599 605.
25. Morin L. P. Allen C. N. (2006) The circadian visual system, 2005. Brain Res. Rev. 51, 1 60.
26. Pakhotin P., Harmar A. J., Verkhratsky A. Piggins H. (2006) VIP receptors control excitability of suprachiasmatic nuclei. Pflugers Arch. Eur. J. Physiol. 452, 7 15.
27. Panda S., Hogenesch J. B. Kay S. A. (2002) Circadian rhythms from flies to human. Nature 417, 329 335.
28. Piggins H. D. (2002) Human clock genes. Ann. Med. 34, 394 400.
29. Piggins H. D. Cutler D. J. (2003) The roles of vasoactive intestinal polypeptide in the mammalian circadian clock. J. Endocrinol. 177, 7 15.
30. Piggins H. D., Antle M. C. Rusak B. (1995) Neuropeptides phase-shift the mammalian circadian pacemaker. J. Neurosci. 15, 5612 5622.
31. Pittendrigh C. S. Daan S. (1976) Functional-analysis of circadian pacemakers in nocturnal rodents. 1. Stability and lability of spontaneous frequency. J. Comp. Physiol. 106, 223 252.
32. Quintero J. E., Kuhlman S. J. McMahon D. G. (2003) The biological clock nucleus: a multiphasic oscillator network regulated by light. J. Neurosci. 23, 8070 8076.
33. Reed H. E., Meyer-Spasche A., Cutler D. J., Coen C. W. Piggins H. D. (2001) Vasoactive intestinal polypeptide (VIP) phase-shifts the rat suprachiasmatic nucleus clock in vitro. Eur. J. Neurosci. 13, 839 843.
34. Reppert S. M. Weaver D. R. (2002) Coordination of circadian timing in mammals. Nature 418, 935 941.
35. Rusak B. Zucker I. (1979) Neural regulation of circadian rhythms. Physiol. Rev. 59, 449 526.
36. Schwartz W. J. Zimmerman P. (1990) Circadian timekeeping in Balb/C and C57bl/6 inbred mouse strains. J. Neurosci. 10, 3685 3694.
37. Vosko A. M., Schroeder A., Loh D. H. Colwell C. S. (2007) Vasoactive intestinal peptide and the mammalian circadian system. Gen. Comp. Endocrinol. 152, 165 175.
38. Watanabe K., Vanecek J. Yamaoka S. (2000) In vitro entrainment of the circadian rhythm of vasopressin-releasing cells in suprachiasmatic nucleus by vasoactive intestinal polypeptide. Brain Res. 877, 361 366.
39. Weaver D. R. (1998) The suprachiasmatic nucleus: a 25-year retrospective. J. Biol. Rhythms 13, 100 112.
40. Welsh D. K., Logothetis D. E., Meister M. Reppert S. M. (1995) Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 14, 697 706.
41. Yamaguchi S., Mitsui S., Miyake S., Yan L., Onishi H., Yagita K., Suzuki M., Shibata S., Kobayashi M. Okamura H. (2000) The 5′ upstream region of mPer1 gene contains two promoters and is responsible for circadian oscillation. Curr. Biol. 10, 873 876.
42. Yamaguchi S., Isejima H., Matsuo T., Okura R., Yagita K., Kobayashi M. Okamura H. (2003) Synchronization of cellular clocks in the suprachiasmatic nucleus. Science 302, 1408 1412.