Efficient transformation of small hepatocytes into insulin-expressing cells by forced expression of Pdx1

Journal of Hepato-Biliary-Pancreatic Surgery

Volumn 15, Issue 4, 2008, Pages 403-409

  Kawasaki, Hiroyuki ^a   Mizuguchi, Toru ^a   Oshima, Hideki ^a   Nobuoka, Takayuki ^a   Shibata, Toshihito ^a   Kaji, Shinsuke ^a   Kokai, Yasuo ^a   Katsuramaki, Tadashi ^a   Mitaka, Toshihiro ^a   Hirata, Koichi ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Genetic transformation; Insulin; Pancreatic endocrine cells; Pdx1; Small hepatocytes

Indexed keywords

ADENOVIRUS VECTOR; GLUCAGON; INSULIN; MESSENGER RNA; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 3; PANCREAS HORMONE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR PDX 1;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL MATURATION; CELL TRANSFORMATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENDOCRINE CELL; GENE EXPRESSION; GENETIC TRANSDUCTION; LIVER CELL; MALE; NONHUMAN; PANCREAS CELL; PROTEIN INDUCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; GLUCAGON; HEPATOCYTES; HOMEODOMAIN PROTEINS; INSULIN; MALE; MICROSCOPY, CONFOCAL; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANS-ACTIVATORS;

EID: 48749090722     PISSN: 09441166     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00534-007-1318-2     Document Type: Article

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