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Volumn 4, Issue 4, 2008, Pages 319-326

Bazedoxifene: A selective estrogen-receptor modulator

Author keywords

Bazedoxifene; Menopause; Osteopenia; Osteoporosis; Selective estrogen receptor modulators

Indexed keywords

ALENDRONIC ACID; APRELA; BAZEDOXIFENE; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; CONJUGATED ESTROGEN; ESTROGEN; GESTAGEN; IBANDRONIC ACID; IBUPROFEN; MEDROXYPROGESTERONE; PARATHYROID HORMONE; PARATHYROID HORMONE[1-34]; PLACEBO; RALOXIFENE; RISEDRONIC ACID; SELECTIVE ESTROGEN RECEPTOR MODULATOR; STRONTIUM RANELATE; TAMOXIFEN; VITAMIN D;

EID: 48649103293     PISSN: 17455057     EISSN: 17455065     Source Type: Journal    
DOI: 10.2217/17455057.4.4.319     Document Type: Article
Times cited : (4)

References (25)
  • 1
    • 0037434618 scopus 로고    scopus 로고
    • Selective estrogen-receptor modulators - mechanisms of action and application to clinical practice
    • Riggs BL, Hartmann LC: Selective estrogen-receptor modulators - mechanisms of action and application to clinical practice. N. Engl. J. Med. 348(7), 618-629 (2003).
    • (2003) N. Engl. J. Med , vol.348 , Issue.7 , pp. 618-629
    • Riggs, B.L.1    Hartmann, L.C.2
  • 2
    • 34248585154 scopus 로고    scopus 로고
    • Bazedoxifene: A third-generation selective estrogen receptor modulator for treatment of postmenopausal osteoporosis
    • Stump AL, Kelley KW, Wensel TM: Bazedoxifene: a third-generation selective estrogen receptor modulator for treatment of postmenopausal osteoporosis. Ann. Pharmacother. 41, 833-839 (2007).
    • (2007) Ann. Pharmacother , vol.41 , pp. 833-839
    • Stump, A.L.1    Kelley, K.W.2    Wensel, T.M.3
  • 3
    • 48649094681 scopus 로고    scopus 로고
    • NIH Consensus Development Panel on Osteoporosis Prevention D, and Therapy: Osteoporosis: prevention, diagnosis, and therapy. JAMA 285(6), 785-795 (2001).
    • NIH Consensus Development Panel on Osteoporosis Prevention D, and Therapy: Osteoporosis: prevention, diagnosis, and therapy. JAMA 285(6), 785-795 (2001).
  • 4
    • 33846492855 scopus 로고    scopus 로고
    • Bone Health and Osteoporosis
    • US Department of Health and Human Services:, Rockville, MD, USA. Public Health Service, Office of the Surgeon General
    • US Department of Health and Human Services: Bone Health and Osteoporosis: a Report of the Surgeon General. Rockville, MD, USA. Public Health Service, Office of the Surgeon General (2004).
    • (2004) a Report of the Surgeon General
  • 5
    • 84967614664 scopus 로고    scopus 로고
    • Riggs BL, Khosla S, Melton LJ 3rd: Sex steroids and the construction and conservation of the adult skeleton. Endocr. Rev 23(3), 279-302 (2002).
    • Riggs BL, Khosla S, Melton LJ 3rd: Sex steroids and the construction and conservation of the adult skeleton. Endocr. Rev 23(3), 279-302 (2002).
  • 6
    • 0347186069 scopus 로고    scopus 로고
    • Recency and duration of postmenopausal hormone therapy: Effects on bone mineral density and fracture risk in the National Osteoporosis Risk Assessment (NORA) study
    • Barrett-Connor E, Wehren LE, Sins ES et al.: Recency and duration of postmenopausal hormone therapy: effects on bone mineral density and fracture risk in the National Osteoporosis Risk Assessment (NORA) study. Menopause 10(5), 412-419 (2003).
    • (2003) Menopause , vol.10 , Issue.5 , pp. 412-419
    • Barrett-Connor, E.1    Wehren, L.E.2    Sins, E.S.3
  • 7
    • 33745239729 scopus 로고    scopus 로고
    • Management of osteoporosis in postmënopausal women: 2006 position statement of The North American Menopause Society
    • North American Menopause Society
    • North American Menopause Society: Management of osteoporosis in postmënopausal women: 2006 position statement of The North American Menopause Society. Menopause 13 (3), 340-367 (2006).
    • (2006) Menopause , vol.13 , Issue.3 , pp. 340-367
  • 8
    • 0037255847 scopus 로고    scopus 로고
    • Pharmacokinetics of selective estrogen receptor modulators
    • Morello KC, Wurz CT, DeGregorio MW: Pharmacokinetics of selective estrogen receptor modulators. Clin. Pharmacokinet. 42, 361-372 (2003).
    • (2003) Clin. Pharmacokinet , vol.42 , pp. 361-372
    • Morello, K.C.1    Wurz, C.T.2    DeGregorio, M.W.3
  • 9
    • 48649100881 scopus 로고    scopus 로고
    • Evista® raloxifene hydrochloride, package insert. Eli Lilly and Company, IN, USA, July 2003
    • Evista® (raloxifene hydrochloride), package insert. Eli Lilly and Company, IN, USA, July 2003.
  • 10
    • 0035686794 scopus 로고    scopus 로고
    • Developing a SERM: Stringent preclinical selection criteria leading to an acceptable candidate (WAY- 140424) for clinical evalution
    • Komm BS, Lyttle CR: Developing a SERM: stringent preclinical selection criteria leading to an acceptable candidate (WAY- 140424) for clinical evalution. Ann. NY Acad. Sci. 949, 317-326 (2001).
    • (2001) Ann. NY Acad. Sci , vol.949 , pp. 317-326
    • Komm, B.S.1    Lyttle, C.R.2
  • 11
    • 0035942513 scopus 로고    scopus 로고
    • Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens
    • Miller CP, Collini MD, Tran BD et al.: Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens. J. Med. Chem. 44(11), 1654-1657 (2001).
    • (2001) J. Med. Chem , vol.44 , Issue.11 , pp. 1654-1657
    • Miller, C.P.1    Collini, M.D.2    Tran, B.D.3
  • 12
    • 23844531615 scopus 로고    scopus 로고
    • Bazedoxifene acetate: A selective estrogen receptor modulator with improved selectivity
    • Komm BS, Kharode YF, Bodine PV, Harris HA, Miller CP, Lyttle CR; Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity. Endocrinology 146(9), 3999-4008 (2005).
    • (2005) Endocrinology , vol.146 , Issue.9 , pp. 3999-4008
    • Komm, B.S.1    Kharode, Y.F.2    Bodine, P.V.3    Harris, H.A.4    Miller, C.P.5    Lyttle, C.R.6
  • 13
    • 34248598671 scopus 로고    scopus 로고
    • Absolute/ relative binavailability of bazedoxifene acetate in healthy postmenopausal women
    • Abstract P43
    • Patat A, McKeand W, Baird-Bellaire S, Ermer J, LeCoz F: Absolute/ relative binavailability of bazedoxifene acetate in healthy postmenopausal women. Clin. Pharmacol. Ther. 73, (2003) (Abstract P43).
    • (2003) Clin. Pharmacol. Ther , pp. 73
    • Patat, A.1    McKeand, W.2    Baird-Bellaire, S.3    Ermer, J.4    LeCoz, F.5
  • 14
    • 34248583759 scopus 로고    scopus 로고
    • Bazedoxifene acetate dose proportionality in healthy, postmenopausal women
    • Abstract P46
    • Ermer J, McKeand W, Sullivan P, Parker V, Orczyk G: Bazedoxifene acetate dose proportionality in healthy, postmenopausal women. Clin. Pharmacol. Ther. 73, (2003) (Abstract P46).
    • (2003) Clin. Pharmacol. Ther , pp. 73
    • Ermer, J.1    McKeand, W.2    Sullivan, P.3    Parker, V.4    Orczyk, G.5
  • 15
    • 34248583759 scopus 로고    scopus 로고
    • Bazedoxifene acetate metabolic disposition in healthy, postmenopausal women
    • Abstract P47
    • Chandrasekaran A, Ermer J, McKeand W et al.: Bazedoxifene acetate metabolic disposition in healthy, postmenopausal women. Clin. Pharmacol. Ther 73, (2003) (Abstract P47).
    • (2003) Clin. Pharmacol. Ther , pp. 73
    • Chandrasekaran, A.1    Ermer, J.2    McKeand, W.3
  • 17
    • 0035686794 scopus 로고    scopus 로고
    • Developing a SFRM: Stringent preclinical selection criteria leading to an acceptable candidate (WAY- 140424) for clinical evaluation
    • Komm BS, Lyttle CR: Developing a SFRM: stringent preclinical selection criteria leading to an acceptable candidate (WAY- 140424) for clinical evaluation. Ann. NY Acad. Sci. 949, 317-326 (2001).
    • (2001) Ann. NY Acad. Sci , vol.949 , pp. 317-326
    • Komm, B.S.1    Lyttle, C.R.2
  • 19
    • 19544386490 scopus 로고    scopus 로고
    • Endometrial effects of bazedoxifene acetate, a novel selective estrogen receptor modulator, in postmenopausal women
    • Ronkin S, Northington R, Baracat E et al.: Endometrial effects of bazedoxifene acetate, a novel selective estrogen receptor modulator, in postmenopausal women. Obstet. Gynecol. 105(6), 1397-1404 (2005).
    • (2005) Obstet. Gynecol , vol.105 , Issue.6 , pp. 1397-1404
    • Ronkin, S.1    Northington, R.2    Baracat, E.3
  • 21
    • 34248574997 scopus 로고    scopus 로고
    • Effects of bazedoxifene TSE-424, a novel tissue selective estrogen receptor modulator SERM, on the incidence of breast pain
    • Abstract
    • Boudes F, Ronkin S, Korner P, Baracat E, Constantine G: Effects of bazedoxifene TSE-424, a novel tissue selective estrogen receptor modulator SERM, on the incidence of breast pain. Osteoporos. Int. 14 (Suppl. 7), S14 (2003) (Abstract).
    • (2003) Osteoporos. Int , vol.14 , Issue.SUPPL. 7
    • Boudes, F.1    Ronkin, S.2    Korner, P.3    Baracat, E.4    Constantine, G.5
  • 22
    • 19544386490 scopus 로고    scopus 로고
    • Endometrial offects of bazedoxifene acetate, a novel selective estrogen receptor modulator, in postmenopausal women
    • Ronkin S, Northington R, Baracat E et al.: Endometrial offects of bazedoxifene acetate, a novel selective estrogen receptor modulator, in postmenopausal women. Obstet. Gynecol. 105, 1397-1404 (2005).
    • (2005) Obstet. Gynecol , vol.105 , pp. 1397-1404
    • Ronkin, S.1    Northington, R.2    Baracat, E.3
  • 23
    • 0000327721 scopus 로고    scopus 로고
    • TSE-424, a novel tissue selective estrogen, reduces biochemical indices of bone metabolism in a dose related fashion
    • Abstract
    • Ronkin S, Clarke L, Boudes P, Constantine G: TSE-424, a novel tissue selective estrogen, reduces biochemical indices of bone metabolism in a dose related fashion. J. Bone Miner, Res. 16, S413 (2001) (Abstract).
    • (2001) J. Bone Miner, Res , vol.16
    • Ronkin, S.1    Clarke, L.2    Boudes, P.3    Constantine, G.4
  • 24
    • 34248574997 scopus 로고    scopus 로고
    • Effects of bazedoxifene (TSE-424), a novel tissue selective estrogen receptor modulator (SERM), on the incidence of breast pain
    • Abstract
    • Boudes P, Ronkin S, Korner P, Baracat E, Constantine G: Effects of bazedoxifene (TSE-424), a novel tissue selective estrogen receptor modulator (SERM), on the incidence of breast pain. Osteoporos. Int. 14, S14 (2003) (Abstract).
    • (2003) Osteoporos. Int , vol.14
    • Boudes, P.1    Ronkin, S.2    Korner, P.3    Baracat, E.4    Constantine, G.5
  • 25
    • 41849138667 scopus 로고    scopus 로고
    • Effects of bazedoxifene on bone mineral density and turnover in postmenopausal women: 2-year results of a randomized, double-blind, placebo- and active-controlled Study
    • Miller PD, Chines A, Christiansen C et al.: Effects of bazedoxifene on bone mineral density and turnover in postmenopausal women: 2-year results of a randomized, double-blind, placebo- and active-controlled Study. J. Bone Miner. Ref. 23(4), 525-535 (2008).
    • (2008) J. Bone Miner. Ref , vol.23 , Issue.4 , pp. 525-535
    • Miller, P.D.1    Chines, A.2    Christiansen, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.