The course of depressive symptoms in older adults with comorbid major depression and dysthymia

American Journal of Geriatric Psychiatry

Volumn 16, Issue 4, 2008, Pages 300-309

  Hybels, Celia F ^a   Pieper, Carl F ^b   Blazer, Dan G ^a   Steffens, David C ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Depression; Dysthymia; Remission

Indexed keywords

ADULT; AGED; AGING; ARTICLE; CLINICAL RESEARCH; COMORBIDITY; CONTROLLED STUDY; DEPRESSION; DIAGNOSTIC ACCURACY; DIAGNOSTIC INTERVIEW SCHEDULE; DYSTHYMIA; FEMALE; FOLLOW UP; GERIATRIC PATIENT; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MONTGOMERY ASBERG DEPRESSION RATING SCALE; NEUROLOGIC EXAMINATION; REMISSION; COHORT ANALYSIS; DAILY LIFE ACTIVITY; DISEASE COURSE; HOSPITAL PATIENT; MARRIAGE; MIDDLE AGED; OUTPATIENT; PATHOPHYSIOLOGY; PROPORTIONAL HAZARDS MODEL; TIME;

ACTIVITIES OF DAILY LIVING; AGED; COHORT STUDIES; COMORBIDITY; DEPRESSION; DEPRESSIVE DISORDER; DISEASE PROGRESSION; DYSTHYMIC DISORDER; FEMALE; FOLLOW-UP STUDIES; HUMANS; INPATIENTS; MALE; MARITAL STATUS; MIDDLE AGED; OUTPATIENTS; PROPORTIONAL HAZARDS MODELS; REMISSION INDUCTION; TIME FACTORS;

EID: 48649087958     PISSN: 10647481     EISSN: 15457214     Source Type: Journal    
DOI: 10.1097/JGP.0b013e318162f15f     Document Type: Article

References (40)

1. Keller MB, Shapiro RW: "Double depression": superimposition of acute depressive episodes on chronic depressive disorders. Am J Psychiatry 1982; 139:438-442
2. Keller MB, Lavori PW, Endicott J, et al: "Double depression": two-year follow-up. Am J Psychiatry 1983; 140:689-694
3. Spitzer RL, Endicott J, Robins E: Research diagnostic criteria: rationale and reliability. Arch Gen Psychiatry 1978; 35:773-782
4. Williams JBW, Spitzer RL: Research diagnostic criteria and DSM-III: an annotated comparison. Arch Gen Psychiatry 1982; 39:1283-1289
5. Keller MB, Hirshfeld RMA, Hanks D: Double depression: a distinctive subtype of unipolar depression. J Affect Disord 1997; 45:65-73
6. Klein DN, Shankman SA, Rose S: Ten-year prospective follow-up study of the naturalistic course of dysthymic disorder and double depression. Am J Psychiatry 2006; 163:872-880
7. Bellino S, Patria L, Ziero S, et al: Clinical features of dysthymia and age: a clinical investigation. Psychiatry Res 2001; 103:219-228
8. Devanand DP, Nobler MS, Singer T, et al: Is dysthymia a different disorder in the elderly? Am J Psychiatry 1994; 151:1592-1599
9. Hinrichsen GA: Recovery and relapse from major depressive disorder in the elderly. Am J Psychiatry 1992; 149:1575-1579
10. Devanand DP, Kim MK, Paykina N, et al: Adverse life events in elderly patients with major depression or dysthymic disorder and in healthy control subjects. Am J Geriatr Psychiatry 2002; 10:265-274
11. Mueller TI, Kohn R, Leventbal N, et al: The course of depression in elderly patients. Am J Geriatr Psychiatry 2004; 12:22-29
12. Costa E, Barreto SM, Ucboa E, et al: Prevalence of International Classification of Diseases, 10th Revision common mental disorders in the elderly in a Brazilian community: The Bambui Health Ageing Study. Am J Geriatr Psychiatry 2007; 15:17-27
13. Beekman ATF, Geerlings SW, Deeg DJH, et al: The natural history of late-life depression. Arch Gen Psychiatry 2002; 59:605-611
14. Beekman ATF, Deeg DJH, Smit JH, et al: Dysthymia in later life: a study in the community. J Affect Disord 2004; 81:191-199
15. Katon WJ, Fan M, Lin EHB, et al: Depressive symptom deterioration in a large primary care-based elderly cohort. Am J Geriatr Psychiatry 2006; 14:246-254
16. Hybels CF, Blazer DG, Sreffens DC: Predictors of partial remission in older patients treated for major depression: the role of comorbid dysthymia. Am J Geriatr Psychiatry 2005; 13:713-721
17. Kivela SL, Pahkala K: The prognosis of depression in old age. Int Psychogeriatr 1989; 1:119-133
18. Devanand DP, Turret N, Moody J, et al: Personality disorders in elderly patients with dysthymic disorder. Am J Geriatr Psychiatry 2000; 8:188-195
19. Oxman TE, Barrett JE, Sengupta A, et al: The relationship of aging and dysthymia in primary care. Am J Geriatr Psychiatry 2000; 8:318-326
20. Alexopoulos GS, Meyers BS, Young RC, et al: Recovery in geriatric depression. Arch Gen Psychiatry 1996; 53:305-312
21. Murphy E: The prognosis of depression in old age. Br J Psychiatry 1983; 142:111-119
22. Bosworth HB, Hays JC, George LK, et al: Psychosocial and clinical predictors of unipolar depression outcome in older adults. Int J Geriatr Psychiatry 2002; 17:238-246
23. Bosworth HB, McQuoid DR, George LK, et al: Time-to-remission from geriatric depression. Am J Geriatr Psychiatry 2002; 10:551-559
24. Steffens DC, McQuoid DR, Krishnan KRR: Partial response as a predictor of outcome in geriatric depression. Am J Geriatr Psychiatry 2003; 11:340-348
25. Steffens DC, McQuoid DR: Impact of symptoms of generalized anxiety disorder on the course of late-life depression. Am J Geriatr Psychiatry 2005; 13:40-47
26. American Psychiatric Association. DSM-IV: Diagnostic and Statistical Manual of Mental Disorders. Washington DC, American Psychiatric Association, 1994
27. Steffens DC, McQuoid DR, Krishnan KR: The Duke Somatic Treatment Algorithm for Geriatric Depression (STAGED) approach. Psychopharmacol Bull 2002; 36:58-68
28. Folstein MF, Folstein SE, McHugh P: Mini-mental state: a practical method for grading the cognitive state of patients for clinicians. J Psychiatr Res 1975; 12:189-198
29. Blazer D, Hughes DC, George LK: Age and impaired subjective support: predictors of depressive symptoms at one-year follow-up. J Nerv Ment Dis 1992; 180:172-178
30. Robins LN, Helzer JE, Croughan J, et al: National Institute of Mental Health Diagnostic Interview Schedule: its history, characteristics, and validity. Arch Gen Psychiatry 1981; 38:381-389
31. Montgomery SA, Asberg M: A new depression scale designed to be sensitive to change. Br J Psychiatry 1979; 134:382-389
32. Landerman R, George LK, Campbell RT, et al: Alternative models of the stress buffering hypothesis. Am J Community Psychol 1989; 17:625-641
33. Allison PD. Survival Analysis Using the SAS System. Cary, NC, SAS Institute, 1995
34. SAS Institute. Statistical Analysis System, Version 9. Cary, NC, SAS Institute, 2004
35. Bryk A, Raudenbush S. Hierarchical Linear Models: Applications and Data Analysis Methods. Newbury Park, CA, Sage, 1992
36. Guy W. ECDEU: Assessment Manual for Psychopharmacology. Revised (DHEW Publ No ADM 76-338). Rockville, MD, US Department of Health, Education and Welfare, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, NIMH Psychopharmacology Research Branch, Division of Extramural Research Program, 1976
37. Rush AJ, Kraemer HC, Sackeim HA, et al: Report by the ACNP task force on response and remission in major depressive disorder. Neuropsychopharmacology 2006; 31:1841-1853
38. Blazer DG: Severe episode of depression in late life: the long road to recovery. Am J Psychiatry 1996; 153:1620-1623
39. Holm-Denoma JM, Berlim MT, Fleck MPA, et al: Double depression in adult psychiatric outpatients in Brazil: distinct from major depression? Psychiatry Res 2006; 144:191-196
40. Klein DN, Taylor EB, Harding K, et al: Double depression and episodic major depression: demographic, clinical, familial, personality, and socioenvironmental characteristics and short-term outcome. Am J Psychiatry 1988; 145:1226-1231