Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers

Gastroenterology

Volumn 135, Issue 2, 2008, Pages 711-712

  Speetjens, Frank M ^a   Kuppen, Peter J K ^a   Morreau, Hans ^a   van der Burg, Sjoerd H ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER VACCINE; CASPASE 5-1; GAMMA INTERFERON; TAF1B PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2-1; U 79260 1 PROTEIN;

CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; COLORECTAL CANCER; DENDRITIC CELL; ENZYME LINKED IMMUNOSPOT ASSAY; FRAMESHIFT MUTATION; GENE EXPRESSION; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOGENICITY; LETTER; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 48549099797     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2008.04.040     Document Type: Letter

References (4)

1. Schwitalle Y., Kloor M., Eiermann S., et al. Immune response against frameshift-induced neopeptides in HNPCC patients and healthy HNPCC mutation carriers. Gastroenterology 134 (2008) 988-997
2. Speetjens F.M., Lauwen M.M., Franken K.L., et al. Prediction of the immunogenic potential of frame shift mutated antigens in microsatellite instable cancer. Int J Cancer 15 (2008) 838-845
3. Rock K.L., and Shen L. Cross-presentation: underlying mechanisms and role in immune surveillance. Immunol Rev 207 (2005) 166-183
4. Melief C.J. Mini-review: REGULATION of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross-priming and direct priming?. Eur J Immunol 33 (2003) 2645-2654