Functional central hypothyroidism in the elderly

Aging Clinical and Experimental Research

Volumn 20, Issue 3, 2008, Pages 207-210

  Sell, Maren A ^a   Schott, Matthias ^a   Tharandt, Lutz ^b   Cissewski, Klaus ^b   Scherbaum, Werner A ^a   Willenberg, Holger S ^a  

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^b Doctor's Office for Endocrinology   (Germany)

Author keywords

Aging; Hypothyroidism; Pituitary; Thyroid gland; Thyrotropin releasing hormone

Indexed keywords

LIOTHYRONINE; PROTIRELIN; THYROID PEROXIDASE ANTIBODY; THYROTROPIN; THYROXINE;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; AGING; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; ELDERLY CARE; FEMALE; HUMAN; HYPOPITUITARISM; HYPOTHYROIDISM; LIOTHYRONINE BLOOD LEVEL; MALE; NORMAL HUMAN; PATIENT SELECTION; THYROID FUNCTION TEST; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL;

EID: 48449105067     PISSN: 15940667     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03324770     Document Type: Article

References (12)

1. Levy EG. Thyroid disease in the elderly. Med Clin North Am 1991; 75: 151-67.
2. Harman SM, Wehmann RE, Blackman MR. Pituitary-thyroid hormone economy in healthy aging men: basal indices of thyroid function and thyrotropin responses to constant infusions of thyrotropin releasing hormone. J Clin Endocrinol Metab 1984; 58: 320-6.
3. Snyder PJ, Utiger RD. Response to thyrotropin releasing hormone (TRH) in normal man. J Clin Endocrinol Metab 1972; 34: 380-5.
4. Erfurth EM, Norden NE, Hedner P, Nilsson A, Ek L. Normal reference interval for thyrotropin response to thyroliberin: dependence on age, sex, free thyroxine index and basal concentrations of thyrotropin. Clin Chem 1984; 30: 196-9.
5. van Coevorden A, Laurent E, Decoster C, et al. Decreased basal and stimulated thyrotropin secretion in healthy elderly men. J Clin Endocrinol Metab 1989; 69: 177-85.
6. Mariotti S, Barbesino G, Caturegli P, et al. Complex alteration of thyroid function in healthy centenarians. J Clin Endocrinol Metab 1993; 77: 1130-4.
7. Magri F, Muzzoni B, Cravello L, et al. Thyroid function in physiological aging and in centenarians: possible relationships with some nutritional markers. Metabolism 2002; 51: 105-9.
8. Ohara H, Kobayashi T, Shiraishi M, Wada T. Thyroid function of the aged as viewed from the pituitary-thyroid system. Endocrinol Jpn 1974; 21: 377.
9. Mariotti S. Thyroid function and aging: do serum 3,5,3′- triiodothyronine and thyroid-stimulating hormone concentrations give the Janus response? J Clin Endocrinol Metab 2005; 90: 6735-7 (Editorial).
10. Silva JE, Larsen PR. Comparison of iodothyronine 5′-deiodinase and other thyroid hormone-dependent enzyme activities in the cerebral cortex of hypothyroid neonatal rat. Evidence for adaptation to hypothyroidism. J Clin Invest 1982; 70: 1110-23.
11. Visser TJ, Kaplan MM, Leonard JL, Larsen PR. Evidence for two pathways of iodothyronine 5′-deiodination in rat pituitary that differ in kinetics, propylthiouracil sensitivity, and response to hypothyroidism. J Clin Invest 1983; 71: 992-1002.
12. Christoffolete MA, Ribeiro R, Singru P, et al. Atypical expression of type 2 iodothyronine deiodinase in thyrotrophs explains the thyroxine-mediated pituitary TSH feedback mechanism. Endocrinology 2006; 147: 1735-43.