Swine hepatitis E virus in rural southern China: Genetic characterization and experimental infection in rhesus monkeys (Macaca mulatta)

Journal of Gastroenterology

Volumn 43, Issue 7, 2008, Pages 565-570

  Ji, Yanli ^a   Zhu, Yonghong ^a   Liang, Jingrui ^a   Wei, Xianfei ^b   Yang, Xi ^a   Wang, Ling ^a   Li, Lingjun ^a   Chang, Yibin ^a   Tang, Ronglan ^b   Zhuang, Hui ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b Liuzhou Medical College   (China)

Author keywords

Hepatitis E virus; Macaca mulatta; Pathogenicity; Phylogeny; Swine

Indexed keywords

ALANINE AMINOTRANSFERASE; HEPATITIS E ANTIBODY; VIRUS RNA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHINA; CROSS INFECTION; FECES ANALYSIS; GENETIC ANALYSIS; GENOTYPE; HEPATITIS E; HEPATITIS E VIRUS; HISTOPATHOLOGY; INOCULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PIG FARMING; PRIORITY JOURNAL; RESERVOIR; RHESUS MONKEY; RURAL AREA; SEROCONVERSION; SWINE; VIREMIA; VIRUS CHARACTERIZATION; VIRUS ISOLATION; VIRUS SHEDDING; VIRUS STRAIN; VIRUS TRANSMISSION; VIRUS VIRULENCE;

ALANINE TRANSAMINASE; ANIMALS; CHINA; DISEASE RESERVOIRS; FECES; HEPATITIS E; HEPATITIS E VIRUS; LIVER; MACACA MULATTA; MALE; RNA, VIRAL; RURAL HEALTH; SEQUENCE ANALYSIS, RNA; SWINE; SWINE DISEASES;

EID: 48449103173     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-008-2196-3     Document Type: Article

References (29)

1. Emerson SU, Purcell RH. Hepatitis E virus. Rev Med Virol 2003;13:145-154.
2. Wang L, Zhuang H. Hepatitis E: An overview and recent advances in vaccine research. World J Gastroenterol 2004;10:2157-2162.
3. Benowal M, Kumar A, Kar P, Jilani N, Sharma JB. Prevalence and severity of acute viral hepatitis and fulminant hepatitis during pregnancy: A prospective study from north India. Indian J Med Microbiol 2003;21:184-185.
4. Hussaini SH, Skidmore SJ, Richardson P, Sherratt LM, Cooper BT, O'Grady JG. Severe hepatitis E infection during pregnancy. J Viral Hepatitis 1997;4:51-54.
5. Lu L, Li CH, Hagedorn CH. Phylogenetic analysis of global hepatitis E virus sequences: Genetic diversity, subtypes and zoonosis. Rev Med Virol 2006;16:5-36.
6. Schlauder GG, Mushahwar IK. Genetic heterogeneity of hepatitis E virus. J Med Virol 2001;65:282-292.
7. Meng XJ, Purcell RH, Halbur PG, Lehman JR, Webb DM, Tsareva TS, et al. A novel virus in swine is closely related to the human hepatitis E virus. Proc Natl Acad Sci USA 1997;94:9860-9865.
8. Hsieh SY, Meng XJ, Wu YH, Liu ST, Tam AW, Lin DY, et al. Identity of a novel swine hepatitis E virus in Taiwan forming a monophyletic group with Taiwan isolates of human hepatitis E virus. J Clin Microbiol 1999;37:3828-3834.
9. Saad MD, Hussein HA, Bashandy MM, Kamel HH, Earhart KC, Fryauff DJ, et al. Hepatitis E virus infection in work horses in Egypt. Infect Genet Evol 2007;7:368-373.
10. Huang FF, Haqshenas G, Guenette DK, Halbur PG, Schommer SK, Pierson FW, et al. Detection by reverse transcription-PCR and genetic characterization of field isolates of swine hepatitis E virus from pigs in different geographic regions of the United States. J Clin Microbiol 2002;40:1326-1332.
11. Choi IS, Kwon HJ, Shin NR, Yoo HS. Identification of swine hepatitis E virus (HEV) and prevalence of anti-HEV antibodies in swine and human populations in Korea. J Clin Microbiol 2003;41:3602-3608.
12. Zheng YJ, Ge SX, Zhang J, Guo QS, Ng MH, Wang FD, et al. Swine as a principal reservoir of hepatitis E virus that infects humans in eastern China. J Infect Dis 2006;193:1643-1649.
13. Yazaki Y, Mizuo H, Takahashi M, Nishizawa T, Sasaki N, Gotanda Y, et al. Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be food-borne, as suggested by the presence of hepatitis E virus in pig liver as food. J Gen Virol 2003;84:2351-2357.
14. Banks M, Bendall R, Grierson S, Heath G, Mitchell J, Dalton H. Human and porcine hepatitis E virus strains, United Kingdom. Emerg Infect Dis 2004;10:953-955.
15. van der Poel WH, Verschoor F, van der Heide R, Herrera MI, Vivo A, Kooreman M, et al. Hepatitis E virus sequences in swine related to sequences in humans, the Netherlands. Emerg Infect Dis 2001;7:970-976.
16. Meng XJ, Halbur PG, Shapiro MS, Govindarajan S, Bruna JD, Mushahwar IK, et al. Genetic and experimental evidence for cross-species infection by swine hepatitis E virus. J Virol 1998;72:9714-9721.
17. Arankalle VA, Chobe LP, Chadha MS. Type-IV Indian swine HEV infects rhesus monkeys. J Viral Hepatol 2006;13:742-745.
18. Wang YC, Zhang HY, Li Z, Gu WJ, Lan HY, Hao W, et al. Detection of sporadic cases of hepatitis E virus (HEV) infection in China using immunoassays based on recombinant open reading frame 2 and 3 polypeptides from HEV genotype 4. J Clin Microbiol 2001;39:4370-4379.
19. Li K, Zhuang H, Zhu WF. Partial nucleotide sequencing of hepatitis E viruses detected in sera of patients with hepatitis E from 14 cities in China. Chin Med J (Engl) 2002;115:1058-1063.
20. Zhuang H, Cao XY, Liu CB, Wang GM. Epidemiology of hepatitis E in China. Gastroenterol Jpn 1991;26:135-138.
21. Wang YC, Zhang HY, Xia NS, Peng G, Lan HY, Zhuang H, et al. Prevalence, isolation, and partial sequence analysis of hepatitis E virus from domestic animals in China. J Med Virol 2002;67:516-521.
22. Ning HQ, Niu ZX, Yu RS, Zhang PH, Dong SJ, Li Z. Identification of genotype 3 hepatitis E virus in fecal samples from a pig farm located in a Shanghai suburb. Vet Microbiol 2007;121:125-130.
23. Li RC, Ge SX, Li YP, Zheng YJ, Nong Y, Guo QS, et al. Seroprevalence of hepatitis E virus infection, rural southern People's Republic of China. Emerg Infect Dis 2006;12:1682-1688.
24. Ge SX, Guo QS, Li SW, Zhang J, Xia NS. Design and preliminary application of a set of highly sensitive universal RT-PCR primers for detection genotype I/IV hepatitis E virus. Bing Du Xue Bao 2005;21:181-187.
25. Zhang J, Ge SX, Huang GY, Li SW, He ZQ, Wang YB, et al. Evaluation of antibody-based and nucleic acid-based assays for diagnosis of hepatitis E virus infection in a rhesus monkey model. J Med Virol 2003;71:518-526.
26. Erker JC, Desai SM, Schlauder GG, Dawson GJ, Mushahwar IK. A hepatitis E virus variant from the United States: Molecular characterization and transmission in Cynomolgus macaques. J Gen Virol 1999;80:681-690.
27. Meng XJ, Halbur PG, Haynes JS, Tsareva TS, Bruna JD, Royer RL, et al. Experimental infection of pigs with the newly identified swine hepatitis E virus (swine HEV), but not with human strains of HEV. Arch Virol 1998;143:1405-1415.
28. Meng XJ, Wiseman B, Elvinger F, Guenette DK, Toth TE, Engle RE, et al. Prevalence of antibodies to hepatitis E virus in veterinarians working with swine and in normal blood donors in the United States and other countries. J Clin Microbiol 2002;40:117-122.
29. Olsen B, Axelsson-Olsson D, Thelin A, Weiland O. Unexpected high prevalence of IgG-antibodies to hepatitis E virus in Swedish pig farmers and controls. Scand J Infect Dis 2006;38:55-58.