Subject-specific computational simulation of left ventricular flow based on magnetic resonance imaging

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine

Volumn 222, Issue 4, 2008, Pages 475-485

  Long, Quan ^a   Merrifield, R ^b   Xu, X Y ^b   Kilner, P ^c   Firmin, D N ^c   Yang, G Z ^b  

^a BRUNEL UNIVERSITY   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

Blood flow simulation; Computational fluid dynamics; Left ventricle; Magnetic resonance imaging; Patient specific modelling

Indexed keywords

ATOMS; BLOOD; BLOOD VESSELS; COMPUTATIONAL FLUID DYNAMICS; DYNAMICS; FLUID DYNAMICS; FLUID MECHANICS; HEMODYNAMICS; IMPLANTS (SURGICAL); JETS; MAGNETIC RESONANCE; MAGNETIC RESONANCE IMAGING; RESONANCE; VALVES (MECHANICAL); VORTEX FLOW; FLOW PATTERNS; MAGNETISM;

BLOOD FLOW SIMULATION; LEFT VENTRICLE; PATIENT SPECIFIC MODELLING;

FLOW SIMULATION; MAGNETIC RESONANCE IMAGING;

ARTICLE; BIOLOGICAL MODEL; BLOOD FLOW VELOCITY; BLOOD PRESSURE; COMPUTER ASSISTED DIAGNOSIS; COMPUTER SIMULATION; EVALUATION; HEART STROKE VOLUME; HEART VENTRICLE; HISTOLOGY; HUMAN; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY; VALIDATION STUDY;

BLOOD FLOW VELOCITY; BLOOD PRESSURE; COMPUTER SIMULATION; HEART VENTRICLES; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MODELS, CARDIOVASCULAR; STROKE VOLUME;

ANTERIOR POSTERIORS; BLOOD FLOW PATTERNS; BLOOD FLOW SIMULATIONS; COMPUTATIONAL FLUID DYNAMICS SIMULATIONS; COMPUTATIONAL SIMULATION; LEFT VENTRICLES; LEFT VENTRICULAR; PATIENT-SPECIFIC MODELLING;

EID: 48449102576     PISSN: 09544119     EISSN: None     Source Type: Journal    
DOI: 10.1243/09544119JEIM310     Document Type: Article

References (21)

1. Yang, G.-Z. Exploring in vivo blood flow dynamics. IEEE Engng Medicine Biol. Mag., 1998, 17(3), 64-72.
2. Gordon, D. G. The physics of left ventricular ejection and its implications for muscle mechanics. Eur. J. Cardiology, 1976, 4(Suppl.), 87-95.
3. Panerai, R. B., Smaill, B. H., Borst, C., Chamberlain, J. H., and Sayers, B. McA. A model of left ventricular function in the denervated. heart. Trans. ASME, J. Biomed Engng, 1979, 1, 161-71.
4. Peskin, C. S. and McQueen, D. M. Modelling prosthetic heart valves for numerical analysis of blood flow in the heart. J. Comput. Physics, 1980, 37, 113-132.
5. McQueen, D. M. and Peskin, C. S. Computer-assisted design of butterfly bileaflet valves for the mitral position. Scand. J. Thoracic Cardiovascular Surg., 1985, 19, 139-148.
6. Chahboune, B. and Crolet, J. M. Numerical simulation of the blood-wall interaction in the human left ventricle. Eur. Phys. J. Appl. Physics, 1998, 2, 291-297.
7. Peskin, C. S. and McQueen, D. M. Cardiac fluid-dynamics. Crit. Rev. Biomed. Engng, 1992, 20, 451-459.
8. Redaelli, A. and Montevecchi, F. M. Intraventricular pressure drop and aortic blood acceleration as indices of cardic inotropy: a comparison with the first derivative of aortic pressure based on computer fluid dynamics. Med. Engng Physics, 1998, 20, 231-241.
9. Gonzalez, E. and Schoephoerster, R. T. A simulation of three-dimensional systolic flow dynamics in a spherical ventricle: effects of abnormal wall motion. Ann. Biomed. Engng, 1996, 24, 48-57.
10. Verdonck, P., Vierendeels, J., Riemslagh, K., and Dick, E. Left-ventricular pressure gradients: a computer-model simulation. Med. Biological Engng Computing, 1999, 37, 511-515.
11. Thomas, J. D. and Weyman, A. E. Numerical modeling of ventricular filling. Ann. Biomed. Engng, 1992, 20, 19-39.
12. Taylor, T. W. and Yamaguchi, T. Realistic three-dimensional left ventricular ejection determined from computational fluid dynamics. Med. Engng Physics, 1995, 17, 602-608.
13. Saber, N. R., Wood, N. B., Gosman, A. D., Yang, G.-Z., Merrifield, B. D., Gatehouse, P. D., Charrier, C. L., and Firmin, D. N. Progress towards patient-specific computational modeling of the left heart via combination of MRI with CFD. Ann. Biomed. Engng, 2003, 31, 42-52.
14. Saber, N. R., Gosman, A. D., Wood, N. B., Kilner, P. J., Charrier, C. L., and Firmin, D. N. Computational flow modelling of the left ventricle based on in vivo MRI data - initial experience. Ann. Biomed. Engng, 2001, 29, 275-283.
15. Long, Q., Xu, X. Y., Collins, M. W., Griffith, T. M., and Bourne, M. The combination of magnetic resonance angiography and computational fluid dynamics: a critical review. Crit. Rev. Biomed. Engng, 1998, 26(4), 227-276.
16. Long, Q., Xu, X. Y., Ariff, B., Thom, S. A., Hughes, A. D., and Stanton, A. Reconstruction of blood flow patterns in an human carotid bifurcation: a combined CFD and MRI study. J. Magn. Resonance Imaging, 2000, 11, 299-311.
17. Long, Q., Merrifield, R., Yang, G. Z., Kilner, P., Firmin, D., and Xu, X. Y. The influence of inflow boundary conditions to the intra left ventricular flow predictions. Trans. ASME, J. Biomech. Engng, 2003, 125(6), 922-927.
18. Merrifield, R. Patient specific modelling of left ventricular morphology and flow using magnetic resonance imaging and computational fluid dynamics. PhD Thesis, University of London, 2003.
19. Merrifield, R., Long, Q., Xu, X. Y., Kilner, P. J., Firmin, D. N., and Yang, G. Z. Combined CFD/MRI analysis of left ventricular flow. In Medical imaging and augmented reality, Lecture Notes in Computer Science, vol. 3150 (Eds G.-Z. Yang and T. Jiang), 2004, pp. 229-237 (Springer-Verlag, Berlin).
20. Long, Q., Xu, X. Y., Kohler, U., Robertson, M. B., Marchall, I., and Hoskins, P. Quantitative comparison of CFD predicted and MRI measured velocity field in a carotid bifurcation phantom. Biorheology, 2002, 39, 467-474.
21. Zhao, S. Z., Papathanasopoulou, P., Long, Q., Marshall, I., and Xu, X. Y. A comparative study of MRI and image-based CFD for quantification of pulsatile flow in a carotid bifurcation phantom. Ann. Biomed. Engng, 2003, 31(8), 962-971.