Neurokinin-1 receptor mRNA expression differences in brains of HIV-infected individuals

Journal of the Neurological Sciences

Volumn 272, Issue 1-2, 2008, Pages 174-177

  Douglas, Steven D ^a   Lynch, Kevin G ^b   Lai, Jian Ping ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

HIV brain; Isoforms; Neurokinin 1 receptor

Indexed keywords

ISOPROTEIN; MESSENGER RNA; NEUROKININ 1 RECEPTOR;

ADULT; ARTICLE; AUTOPSY; CEREBELLUM; CINGULATE GYRUS; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN TISSUE; MALE; PRIORITY JOURNAL;

ADULT; BRAIN; FEMALE; GENE EXPRESSION REGULATION, VIRAL; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; RECEPTORS, NEUROKININ-1; RNA, MESSENGER;

EID: 48449090028     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2008.04.025     Document Type: Article

References (19)

1. Fong T.M., Anderson S.A., Yu H., Huang R.R., and Strader C.D. Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor. Mol Pharmacol 41 1 (1992) 24-30
2. Caberlotto L., Hurd Y.L., Murdock P., Wahlin J.P., Melotto S., Corsi M., et al. Neurokinin 1 receptor and relative abundance of the short and long isoforms in the human brain. Eur J Neurosci 17 9 (2003) 1736-1746
3. Kage R., Leeman S.E., and Boyd N.D. Biochemical characterization of two different forms of the substance P receptor in rat submaxillary gland. J Neurochem 60 1 (1993) 347-351
4. Mantyh P.W., Rogers S.D., Ghilardi J.R., Maggio J.E., Mantyh C.R., and Vigna S.R. Differential expression of two isoforms of the neurokinin-1 (substance P) receptor in vivo. Brain Res 719 1-2 (1996) 8-13
5. Bohm S.K., Khitin L.M., Smeekens S.P., Grady E.F., Payan D.G., and Bunnett N.W. Identification of potential tyrosine-containing endocytic motifs in the carboxyl-tail and seventh transmembrane domain of the neurokinin 1 receptor. J Biol Chem 272 4 (1997) 2363-2372
6. Li H., Leeman S.E., Slack B.E., Hauser G., Saltsman W.S., Krause J.E., et al. A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization. Proc Natl Acad Sci U S A 94 17 (1997) 9475-9480
7. Sasakawa N., Sharif M., and Hanley M.R. Attenuation of agonist-induced desensitization of the rat substance P receptor by progressive truncation of the C-terminus. FEBS Lett 347 2-3 (1994) 181-184
8. Lai J.P., Cnaan A., Zhao H., and Douglas S.D. Detection of full-length and truncated neurokinin-1 receptor mRNA expression in human brain regions. J Neurosci Methods 168 1 (2008) 127-133
9. Lai J.P., Ho W.Z., Kilpatrick L.E., Wang X., Tuluc F., Korchak H.M., et al. Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation. Proc Natl Acad Sci U S A 103 20 (2006) 7771-7776
10. Douglas S.D., Ho W.Z., Gettes D.R., Cnaan A., Zhao H., Leserman J., et al. Elevated substance P levels in HIV-infected men. Aids 15 15 (2001) 2043-2045
11. Douglas S.D., Cnaan A., Lynch K.G., Benton T., Zhao H., Getters D.R., et al. Elevated substance p levels in HIV-infected women in comparison to HIV-negative women. AIDS Res Hum Retrovir 24 3 (2007) 375-378
12. Lai J.P., Yang J.H., Douglas S.D., Wang X., Riedel E., and Ho W.Z. Quantification of CCR5 mRNA in human lymphocytes and macrophages by real-time reverse transcriptase PCR assay. Clin Diagn Lab Immunol 10 6 (2003) 1123-1128
13. Thompson P.M., Dutton R.A., Hayashi K.M., Toga A.W., Lopez O.L., Aizenstein H.J., et al. Thinning of the cerebral cortex visualized in HIV/AIDS reflects CD4+ T lymphocyte decline. Proc Natl Acad Sci U S A 102 43 (2005) 15647-15652
14. Tomlin D., Kayali M.A., King-Casas B., Anen C., Camerer C.F., Quartz S.R., et al. Agent-specific responses in the cingulate cortex during economic exchanges. Science 312 5776 (2006) 1047-1050
15. Carter A.J., Grauert M., Pschorn U., Bechtel W.D., Bartmann-Lindholm C., Qu Y., et al. Potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890 CL. Proc Natl Acad Sci U S A 97 9 (2000) 4944-4949
16. Botvinick M., Nystrom L.E., Fissell K., Carter C.S., and Cohen J.D. Conflict monitoring versus selection-for-action in anterior cingulate cortex. Nature 402 6758 (1999) 179-181
17. Berton O., Covington 3r.H., Ebner K., Tsankova N.M., Carle T.L., Ulery P., et al. Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses. Neuron 55 2 (2007) 289-300
18. Reed K.L., Fruin A.B., Gower A.C., Gonzales K.D., Stucchi A.F., Andry C.D., et al. NF-kappaB activation precedes increases in mRNA encoding neurokinin-1 receptor, proinflammatory cytokines, and adhesion molecules in dextran sulfate sodium-induced colitis in rats. Dig Dis Sci 50 12 (2005) 2366-2378
19. Simeonidis S., Castagliuolo I., Pan A., Liu J., Wang C.C., Mykoniatis A., et al. Regulation of the NK-1 receptor gene expression in human macrophage cells via an NF-kappa B site on its promoter. Proc Natl Acad Sci U S A 100 5 (2003) 2957-2962