-
1
-
-
48449098910
-
-
Diagnostic and Statistical Manual of Mental Disorders. 4th edition. american psychiatric associate; Washington, DC; 1994
-
Diagnostic and Statistical Manual of Mental Disorders. 4th edition. american psychiatric associate; Washington, DC; 1994
-
-
-
-
2
-
-
48449106925
-
-
International classification of diseases. 10th edition, world health organization, Geneva Switzerland; 1992
-
International classification of diseases. 10th edition, world health organization, Geneva Switzerland; 1992
-
-
-
-
3
-
-
34147168331
-
The lifetime distribution of the incremental societal costs of autism
-
Ganz ML. The lifetime distribution of the incremental societal costs of autism. Arch Pediatr Adolesc Med 2007;161:343-349
-
(2007)
Arch Pediatr Adolesc Med
, vol.161
, pp. 343-349
-
-
Ganz, M.L.1
-
4
-
-
48449093986
-
-
Available from:, Last accessed 12 May 2008
-
Autism Prevalence in the US. Rises to 1 in 150; 2007. Available from: www.autism-soctety.org/site/News2?page=NewsArticle&id=9289 [Last accessed 12 May 2008]
-
Autism Prevalence in the US. Rises to 1 in 150; 2007
-
-
-
5
-
-
7444257916
-
Genetics, statistics and human disease: Analytical retooling for complexity
-
Thornton-Wells TA, Moore JH, Haines JL. Genetics, statistics and human disease: analytical retooling for complexity. Trends Genet 2004;20(12):640-7
-
(2004)
Trends Genet
, vol.20
, Issue.12
, pp. 640-647
-
-
Thornton-Wells, T.A.1
Moore, J.H.2
Haines, J.L.3
-
7
-
-
0242571954
-
Systems biology in neuroscience: Bridging genes to cognition
-
Grant SGN. Systems biology in neuroscience: bridging genes to cognition. Current Opin Neurobiol 2003;13:577-82
-
(2003)
Current Opin Neurobiol
, vol.13
, pp. 577-582
-
-
Grant, S.G.N.1
-
9
-
-
0041883062
-
Is social attachment an addictive disorder?
-
Insel TR. Is social attachment an addictive disorder? Physiol Behav 2003;79(3):351-7
-
(2003)
Physiol Behav
, vol.79
, Issue.3
, pp. 351-357
-
-
Insel, T.R.1
-
11
-
-
33845867765
-
Oxytocin, vasopressin and pair bonding: Implications for autism. Philosoph Trans Royal Soc B
-
Hammock EAD, Young LJ. Oxytocin, vasopressin and pair bonding: implications for autism. Philosoph Trans Royal Soc B Biol Sci 2006;361(1476):2187-98
-
(2006)
Biol Sci
, vol.361
, Issue.1476
, pp. 2187-2198
-
-
Hammock, E.A.D.1
Young, L.J.2
-
12
-
-
33748100237
-
Neuropeptidergic regulation of affiliative behavior and social bonding in animals
-
Lim MM, Young LJ. Neuropeptidergic regulation of affiliative behavior and social bonding in animals. Hormones Behav 2006;50(4):506-17
-
(2006)
Hormones Behav
, vol.50
, Issue.4
, pp. 506-517
-
-
Lim, M.M.1
Young, L.J.2
-
13
-
-
15244362632
-
The neurobiology of pair bonding
-
Young LJ, Wang Z. The neurobiology of pair bonding. Nature Neurosci 2004;7(10):1048-54
-
(2004)
Nature Neurosci
, vol.7
, Issue.10
, pp. 1048-1054
-
-
Young, L.J.1
Wang, Z.2
-
14
-
-
0027338771
-
A role for central vasopressin in pair bonding in monogamous prairie voles
-
Winslow JT, Hastings N, Carter CS, et al. A role for central vasopressin in pair bonding in monogamous prairie voles. Nature 1993;365(6446):545-8
-
(1993)
Nature
, vol.365
, Issue.6446
, pp. 545-548
-
-
Winslow, J.T.1
Hastings, N.2
Carter, C.S.3
-
15
-
-
0023665738
-
Centrally injected arginine vasopressin (AVP) facilitates social memory in rats
-
Le Moal M, Dantzer R, Michaud B, Koob GF. Centrally injected arginine vasopressin (AVP) facilitates social memory in rats. Neurosci Lett 1987;77(3):353-9
-
(1987)
Neurosci Lett
, vol.77
, Issue.3
, pp. 353-359
-
-
Le Moal, M.1
Dantzer, R.2
Michaud, B.3
Koob, G.F.4
-
16
-
-
0028981589
-
V1 vasopressin receptor antisense oligodeoxynucleotide into septum reduces vasopressin binding, social discrimination abilities, and anxiety-related behavior in rats
-
Landgraf R, Gerstberger R, Montkowski A, et al. V1 vasopressin receptor antisense oligodeoxynucleotide into septum reduces vasopressin binding, social discrimination abilities, and anxiety-related behavior in rats. J Neurosci 1995;15(6):4250-8
-
(1995)
J Neurosci
, vol.15
, Issue.6
, pp. 4250-4258
-
-
Landgraf, R.1
Gerstberger, R.2
Montkowski, A.3
-
17
-
-
0030788962
-
Lateral septal vasopressin in rats: Role in social and object recognition?
-
Everts HGJ, Koolhaas JM. Lateral septal vasopressin in rats: role in social and object recognition? Brain Res 1997;760(1-2):1-7
-
(1997)
Brain Res
, vol.760
, Issue.1-2
, pp. 1-7
-
-
Everts, H.G.J.1
Koolhaas, J.M.2
-
18
-
-
0028847954
-
Oxytocin and vasopressin release in the olfactory bulb of parturient ewes: Changes with maternal experience and effects on acetylcholine, γ-aminobutyric acid, glutamate and noradrenaline release
-
Levy F, Kendrick KM, Goode JA, et al. Oxytocin and vasopressin release in the olfactory bulb of parturient ewes: changes with maternal experience and effects on acetylcholine, γ-aminobutyric acid, glutamate and noradrenaline release. Brain Res 1995;669(2):197-206
-
(1995)
Brain Res
, vol.669
, Issue.2
, pp. 197-206
-
-
Levy, F.1
Kendrick, K.M.2
Goode, J.A.3
-
20
-
-
27644476955
-
-
Takayanagi Y, Yoshida M, Bielsky IF, et al. Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice. 2005;102(44):16096-101
-
(2005)
Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice
, vol.102
, Issue.44
, pp. 16096-16101
-
-
Takayanagi, Y.1
Yoshida, M.2
Bielsky, I.F.3
-
21
-
-
23744503329
-
The V1a vasopressin receptor is necessary and sufficient for normal social recognition: A gene replacement study
-
Bielsky IF, Hu S-B, Re X, et al. The V1a vasopressin receptor is necessary and sufficient for normal social recognition: a gene replacement study. Neuron 2005;47(4):503-13
-
(2005)
Neuron
, vol.47
, Issue.4
, pp. 503-513
-
-
Bielsky, I.F.1
Hu, S.-B.2
Re, X.3
-
22
-
-
4544249418
-
Oxytocin, vasopressin, and social recognition in mammals
-
Bielsky IF, Young LJ. Oxytocin, vasopressin, and social recognition in mammals. Peptides 2004;25(9)1565-74
-
(2004)
Peptides
, vol.25
, Issue.9
, pp. 1565-1574
-
-
Bielsky, I.F.1
Young, L.J.2
-
23
-
-
33847398002
-
CD38 is critical for social behaviour by regulating oxytocin secretion
-
Jin D, Liu H-X, Hirai H, et al. CD38 is critical for social behaviour by regulating oxytocin secretion. Nature 2007;446(7131):41-5
-
(2007)
Nature
, vol.446
, Issue.7131
, pp. 41-45
-
-
Jin, D.1
Liu, H.-X.2
Hirai, H.3
-
24
-
-
0032519523
-
Plasma oxytocin levels in autistic children
-
Modahl C, Green LA, Fein D, et al. Plasma oxytocin levels in autistic children. Biol Psychiatry 1998;43(4):270-7
-
(1998)
Biol Psychiatry
, vol.43
, Issue.4
, pp. 270-277
-
-
Modahl, C.1
Green, L.A.2
Fein, D.3
-
25
-
-
0035886219
-
Oxytocin and autistic disorder: Alterations in peptide forms
-
Green L-A, Fein D, Modahl C, et al. Oxytocin and autistic disorder: alterations in peptide forms. Biol Psychiatry 2001;50(8):609-13
-
(2001)
Biol Psychiatry
, vol.50
, Issue.8
, pp. 609-613
-
-
Green, L.-A.1
Fein, D.2
Modahl, C.3
-
26
-
-
21344444796
-
Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population
-
Wu S, Jia M, Ruan Y, et al. Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population. Biol Psychiatry 2005;58(1):74-7
-
(2005)
Biol Psychiatry
, vol.58
, Issue.1
, pp. 74-77
-
-
Wu, S.1
Jia, M.2
Ruan, Y.3
-
27
-
-
0028580206
-
Structural organization of the human oxytocin receptor gene
-
Inoue T, Kimura T, Azuma C, et al. Structural organization of the human oxytocin receptor gene. J Biol Chem 1994;269(51):32451-6
-
(1994)
J Biol Chem
, vol.269
, Issue.51
, pp. 32451-32456
-
-
Inoue, T.1
Kimura, T.2
Azuma, C.3
-
28
-
-
0035087628
-
The "reading the mind in the eyes" test, revised version: A study with normal adults, and adults with Asperger syndrome or high-functioning autism
-
Baron-Cohen S, Wheelwright S, Hill J, et al. The "reading the mind in the eyes" test, revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry Allied Discp 2001;42(2):241-51
-
(2001)
J Child Psychol Psychiatry Allied Discp
, vol.42
, Issue.2
, pp. 241-251
-
-
Baron-Cohen, S.1
Wheelwright, S.2
Hill, J.3
-
29
-
-
33847273564
-
Oxytocin improves "mind reading" in humans
-
Domes G, Heinrichs M, Michel A, et al. Oxytocin improves "mind reading" in humans. Biol Psychiatry 2007;61(6):731-3
-
(2007)
Biol Psychiatry
, vol.61
, Issue.6
, pp. 731-733
-
-
Domes, G.1
Heinrichs, M.2
Michel, A.3
-
30
-
-
20444497343
-
Oxytocin increases trust in humans
-
Kosfeld M, Heinrichs M, Zak PJ, Fischbacher U, Fehr E. Oxytocin increases trust in humans. Nature 2005;435(7042):673-6
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 673-676
-
-
Kosfeld, M.1
Heinrichs, M.2
Zak, P.J.3
Fischbacher, U.4
Fehr, E.5
-
31
-
-
27844437083
-
Oxytocin is associated with human trustworthiness
-
Zak, PJ, Kurzban R, Matzner WT. Oxytocin is associated with human trustworthiness. Horm Behav 2005;48(5):522-7
-
(2005)
Horm Behav
, vol.48
, Issue.5
, pp. 522-527
-
-
Zak, P.J.1
Kurzban, R.2
Matzner, W.T.3
-
32
-
-
0036841902
-
Increased amygdala activation to angry and contemptuous faces in generalized social phobias
-
Stein MB, Goldin PR, Sareen J, et al. Increased amygdala activation to angry and contemptuous faces in generalized social phobias. Arch Gen Psychiatry 59(11):1027-34
-
Arch Gen Psychiatry
, vol.59
, Issue.11
, pp. 1027-1034
-
-
Stein, M.B.1
Goldin, P.R.2
Sareen, J.3
-
33
-
-
30544438866
-
Oxytocin modulates neural circuitry for social cognition and fear in humans
-
Kirsch P, Esslinger C, Chen Q, et al. Oxytocin modulates neural circuitry for social cognition and fear in humans. J Neurosci 2005;25(49):11489-93
-
(2005)
J Neurosci
, vol.25
, Issue.49
, pp. 11489-11493
-
-
Kirsch, P.1
Esslinger, C.2
Chen, Q.3
-
34
-
-
23044456645
-
Neural correlates of genetically abnormal social cognition in Williams syndrome
-
Meyer-Lindenberg A, Hariri AR, Munoz KE, et al. Neural correlates of genetically abnormal social cognition in Williams syndrome. Nat Neurosci 2005;8(8):991-3
-
(2005)
Nat Neurosci
, vol.8
, Issue.8
, pp. 991-993
-
-
Meyer-Lindenberg, A.1
Hariri, A.R.2
Munoz, K.E.3
-
35
-
-
0037209159
-
Oxytocin infusion reduces repetitive behaviours in adults with autistic and Asperger disorder
-
Hollander E, Novotny S, Hanratty M, et al. Oxytocin infusion reduces repetitive behaviours in adults with autistic and Asperger disorder. Neuropsychopharmacol 2003;28(1):193-8
-
(2003)
Neuropsychopharmacol
, vol.28
, Issue.1
, pp. 193-198
-
-
Hollander, E.1
Novotny, S.2
Hanratty, M.3
-
36
-
-
33846624633
-
Oxytocin increases retention of social cognition in autism
-
Hollander E, Bartz J, Chaplin W, et al. Oxytocin increases retention of social cognition in autism. Biol Psychiatry 2006;61(4):498-503
-
(2006)
Biol Psychiatry
, vol.61
, Issue.4
, pp. 498-503
-
-
Hollander, E.1
Bartz, J.2
Chaplin, W.3
-
37
-
-
0035985478
-
-
Kim S-J, Young LJ, Gonen d, et al. Transmission disequilibrium testing of arginine vasopressin receptor 1A (AVPR1A) polymorphisms in autism. Mol Psychiatry 2002;7(5):503-7
-
Kim S-J, Young LJ, Gonen d, et al. Transmission disequilibrium testing of arginine vasopressin receptor 1A (AVPR1A) polymorphisms in autism. Mol Psychiatry 2002;7(5):503-7
-
-
-
-
38
-
-
5444259204
-
Examination of AVPR1a as an autism susceptibility gene
-
Wassink TH, Piven J, Vieland VJ, et al. Examination of AVPR1a as an autism susceptibility gene. Mol Psychaitr 2004;9(10):968-72
-
(2004)
Mol Psychaitr
, vol.9
, Issue.10
, pp. 968-972
-
-
Wassink, T.H.1
Piven, J.2
Vieland, V.J.3
-
39
-
-
33646343746
-
Association between the arginine vasopressin 1a receptor (AVPR1a) gene and autism in a family-based study: Mediation by socialization skills
-
Yirmiya N, Rosenberg, C, Levi S, et al. Association between the arginine vasopressin 1a receptor (AVPR1a) gene and autism in a family-based study: mediation by socialization skills. Mol Psychiatry 2006;11(5):488-94
-
(2006)
Mol Psychiatry
, vol.11
, Issue.5
, pp. 488-494
-
-
Yirmiya, N.1
Rosenberg, C.2
Levi, S.3
-
40
-
-
33644848493
-
Anxiolytic-like activity of oxytocin in male mice: Behavioral and autonomic evidence, therapeutic implications
-
Ring RH, Malberg JE, Potestio L, et al. Anxiolytic-like activity of oxytocin in male mice: behavioral and autonomic evidence, therapeutic implications. Psychopharmacology 2006;185(2):218-25
-
(2006)
Psychopharmacology
, vol.185
, Issue.2
, pp. 218-225
-
-
Ring, R.H.1
Malberg, J.E.2
Potestio, L.3
-
41
-
-
0029093591
-
Bioavailability and pharmacokinetics of sublingual oxytocin in male volunteers
-
De Groot AN, Vree TB, Hekster YA, et al. Bioavailability and pharmacokinetics of sublingual oxytocin in male volunteers. J Pharm Pharmacol 1995;47(7):571-5
-
(1995)
J Pharm Pharmacol
, vol.47
, Issue.7
, pp. 571-575
-
-
De Groot, A.N.1
Vree, T.B.2
Hekster, Y.A.3
-
42
-
-
0003124661
-
Relative conformational rigidity in oxytocin and [1-penicillamine]-oxytocin: A proposal for the relationship of conformational flexibility to peptide hormone agonism and antagonism
-
Meraldi JP, Hruby VJ, Brewster AI. Relative conformational rigidity in oxytocin and [1-penicillamine]-oxytocin: a proposal for the relationship of conformational flexibility to peptide hormone agonism and antagonism. Proc Natl Acad Sci USA 1977;74(4):1373-7
-
(1977)
Proc Natl Acad Sci USA
, vol.74
, Issue.4
, pp. 1373-1377
-
-
Meraldi, J.P.1
Hruby, V.J.2
Brewster, A.I.3
-
43
-
-
0037030644
-
Synthesis and pharmacological evaluation of an analogue of the peptide hormone oxytocin that contains a mimetic of an inverse γ-turn
-
Yuan Z-Q, Blomberg D, Sethson I, et al. Synthesis and pharmacological evaluation of an analogue of the peptide hormone oxytocin that contains a mimetic of an inverse γ-turn. J Med Chem 2002;45(12):2512-9
-
(2002)
J Med Chem
, vol.45
, Issue.12
, pp. 2512-2519
-
-
Yuan, Z.-Q.1
Blomberg, D.2
Sethson, I.3
-
44
-
-
0025274625
-
Conformational and structural considerations in oxytocin-receptor binding and biological activity
-
Hruby VJ, Chow MS, Smith DD. Conformational and structural considerations in oxytocin-receptor binding and biological activity. Ann Rev Pharmacol Toxicol 1990;30:501-34
-
(1990)
Ann Rev Pharmacol Toxicol
, vol.30
, pp. 501-534
-
-
Hruby, V.J.1
Chow, M.S.2
Smith, D.D.3
-
45
-
-
27144548997
-
Introduction of a cis-prolyl mimic in position 7 of the peptide hormone oxytocin does not result in antagonistic activity
-
Wittelsberger A, Patiny L, Slaninova J, et al. Introduction of a cis-prolyl mimic in position 7 of the peptide hormone oxytocin does not result in antagonistic activity. J Med Chem 2005;48(21):6553-62
-
(2005)
J Med Chem
, vol.48
, Issue.21
, pp. 6553-6562
-
-
Wittelsberger, A.1
Patiny, L.2
Slaninova, J.3
-
46
-
-
0036834372
-
Designing peptide receptor agonists and antagonists
-
Hruby VJ. Designing peptide receptor agonists and antagonists. Nat Rev Drug Disc 2002;1(11):847-58
-
(2002)
Nat Rev Drug Disc
, vol.1
, Issue.11
, pp. 847-858
-
-
Hruby, V.J.1
-
47
-
-
0031686987
-
Oxytocin receptor binding and uterotonic activity of carbetocin and its metabolites following enzymatic degradation
-
Engstrøm T, Barth T, Melin P, Vilhardt H. Oxytocin receptor binding and uterotonic activity of carbetocin and its metabolites following enzymatic degradation. Eur J Pharmacol 1998;355(2-3):203-10
-
(1998)
Eur J Pharmacol
, vol.355
, Issue.2-3
, pp. 203-210
-
-
Engstrøm, T.1
Barth, T.2
Melin, P.3
Vilhardt, H.4
-
48
-
-
0037900064
-
Synthesis of biologically active dicarba analogues of the peptide hormone oxytocin using ring-closing metathesis
-
Stymiest JL, Mitchell BF, Wong S, Vederas JC. Synthesis of biologically active dicarba analogues of the peptide hormone oxytocin using ring-closing metathesis. Org Lett 2003;5(1):47-9
-
(2003)
Org Lett
, vol.5
, Issue.1
, pp. 47-49
-
-
Stymiest, J.L.1
Mitchell, B.F.2
Wong, S.3
Vederas, J.C.4
-
49
-
-
0016196626
-
Synthesis of (1,6-α,α′-disminosuberic acid) oxytocin (dicarba-oxytocin)
-
Keller O, Rudiger J. Synthesis of (1,6-α,α′-disminosuberic acid) oxytocin (dicarba-oxytocin). Helv Chim Acta 1974;57(5):1253-9
-
(1974)
Helv Chim Acta
, vol.57
, Issue.5
, pp. 1253-1259
-
-
Keller, O.1
Rudiger, J.2
-
50
-
-
0003588416
-
Neurohypophyseal hormone analog with selective oxytocin-like activities and resistance to enzymatic inactivation. Approach to the design of peptide drugs
-
Walter R, Yamanaka T, Sakakibara S. Neurohypophyseal hormone analog with selective oxytocin-like activities and resistance to enzymatic inactivation. Approach to the design of peptide drugs. Proc Natl Acad Sci USA 1974;71(5):1901-5
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, Issue.5
, pp. 1901-1905
-
-
Walter, R.1
Yamanaka, T.2
Sakakibara, S.3
-
51
-
-
0026443104
-
Orally active, nonpeptide oxytocin antagonists
-
Evans BE, Leighton JL, Rittle KE, et al. Orally active, nonpeptide oxytocin antagonists. J Med Chem 1992;35(21):3919-27
-
(1992)
J Med Chem
, vol.35
, Issue.21
, pp. 3919-3927
-
-
Evans, B.E.1
Leighton, J.L.2
Rittle, K.E.3
-
52
-
-
15644378251
-
Development of orally active oxytocin antagonists, Studies on 1-(1-[4-[20methyl-1-oxidopyridin-3- ylmethyl]piperidin-4-yloxy}-2-methoxybenzoly) piperidin-4-yl)-1,4- dihydrobenz[d] [1,3]oxazin-2-one (L-372,662) and related pyridines
-
Bell IM, Erb JM, Freidenger RM, et al. Development of orally active oxytocin antagonists, Studies on 1-(1-[4-[20methyl-1-oxidopyridin-3- ylmethyl]piperidin-4-yloxy}-2-methoxybenzoly) piperidin-4-yl)-1,4- dihydrobenz[d] [1,3]oxazin-2-one (L-372,662) and related pyridines. J Med Chem 1998;41(12):2146-63
-
(1998)
J Med Chem
, vol.41
, Issue.12
, pp. 2146-2163
-
-
Bell, I.M.1
Erb, J.M.2
Freidenger, R.M.3
-
55
-
-
18344413881
-
Autism and maternally derived aberrations of chromosome 15q
-
Schroer RJ, Phelan MC, Michaelis RC, et al. Autism and maternally derived aberrations of chromosome 15q. Am J Med Genet 1998;76(4):327-36
-
(1998)
Am J Med Genet
, vol.76
, Issue.4
, pp. 327-336
-
-
Schroer, R.J.1
Phelan, M.C.2
Michaelis, R.C.3
-
56
-
-
33645230209
-
GABAergic cerebellar system in autism: A neuropathological and developmental perspective
-
Blatt GJ. GABAergic cerebellar system in autism: a neuropathological and developmental perspective. Int Rev Neurobiol 2005;71:167-78
-
(2005)
Int Rev Neurobiol
, vol.71
, pp. 167-178
-
-
Blatt, G.J.1
-
57
-
-
0022572835
-
Lower Purkinje cell counts in the cerebella of four autistic subjects: Initial findings of the UCLA-NSCA autopsy research report
-
Rivto ER, Freeman BJ, Scheibel AB, et al. Lower Purkinje cell counts in the cerebella of four autistic subjects: initial findings of the UCLA-NSCA autopsy research report. Am J Psychiatry 1986;143(7):862-6
-
(1986)
Am J Psychiatry
, vol.143
, Issue.7
, pp. 862-866
-
-
Rivto, E.R.1
Freeman, B.J.2
Scheibel, A.B.3
-
58
-
-
7644221741
-
A linkage disequilibrium map of the 1-Mb 15q12 GABAA receptor subunit cluster and association to autism
-
Mccauley JL, Olson LM, Delahanty R, et al. A linkage disequilibrium map of the 1-Mb 15q12 GABAA receptor subunit cluster and association to autism. Am J Med Genet Part B Neuropsych Genetics 2004;131(1):51-9
-
(2004)
Am J Med Genet Part B Neuropsych Genetics
, vol.131
, Issue.1
, pp. 51-59
-
-
Mccauley, J.L.1
Olson, L.M.2
Delahanty, R.3
-
59
-
-
0034088447
-
Genetic studies in autistic disorder and chromosome 15
-
Bass MP, Menold MM, Wolpert M, et al. Genetic studies in autistic disorder and chromosome 15. Neurogenetics 2000;2(4):219-26
-
(2000)
Neurogenetics
, vol.2
, Issue.4
, pp. 219-226
-
-
Bass, M.P.1
Menold, M.M.2
Wolpert, M.3
-
60
-
-
33645241651
-
Shared chromosomal susceptibility regions between autism and other mental disorders
-
Chagnon YC. Shared chromosomal susceptibility regions between autism and other mental disorders. Int Rev Neurobiol 2005;71:419-43
-
(2005)
Int Rev Neurobiol
, vol.71
, pp. 419-443
-
-
Chagnon, Y.C.1
-
61
-
-
33645226952
-
GABAergic signalling in the developing cerebellum
-
Takayama C. GABAergic signalling in the developing cerebellum. Int Rev Neurobiol 2005;71:63-94
-
(2005)
Int Rev Neurobiol
, vol.71
, pp. 63-94
-
-
Takayama, C.1
-
62
-
-
0036719162
-
Excitatory actions of GABA during development: The nature of the nurture
-
Ben-Ari Y. Excitatory actions of GABA during development: the nature of the nurture. Nature Rev Neurosci 2002;3(9):728-39
-
(2002)
Nature Rev Neurosci
, vol.3
, Issue.9
, pp. 728-739
-
-
Ben-Ari, Y.1
-
63
-
-
1642580891
-
Opiate state controls bi-directional reward signalling via GABAA receptors in the ventral tegmental area
-
Laviolette SR, Gallegos RA, Henriksen SJ, Van Der Kooy D. Opiate state controls bi-directional reward signalling via GABAA receptors in the ventral tegmental area. Nature Neurosci 2004;7(2):160-9
-
(2004)
Nature Neurosci
, vol.7
, Issue.2
, pp. 160-169
-
-
Laviolette, S.R.1
Gallegos, R.A.2
Henriksen, S.J.3
Van Der Kooy, D.4
-
64
-
-
19044366354
-
The supramammillary nucleus mediates primary reinforcement via GABAA receptors
-
Ikemoto S. The supramammillary nucleus mediates primary reinforcement via GABAA receptors. Neuropsychopharmacology 2005;30:1088-95
-
(2005)
Neuropsychopharmacology
, vol.30
, pp. 1088-1095
-
-
Ikemoto, S.1
-
65
-
-
31344443894
-
Recent advances in the development of treatments for alcohol and cocaine dependence
-
Johnson BA. Recent advances in the development of treatments for alcohol and cocaine dependence. CNS Drugs 2005;19(10):873-96
-
(2005)
CNS Drugs
, vol.19
, Issue.10
, pp. 873-896
-
-
Johnson, B.A.1
-
66
-
-
34547106309
-
Molecular analysis of the GABRB3 gene in autistic patients: An exploratory study
-
Solis-Anez E, Delgado-Luengo W, Borjas-Fuentes L, et al. Molecular analysis of the GABRB3 gene in autistic patients: an exploratory study. Invest Clin 2007;48(2):225-42
-
(2007)
Invest Clin
, vol.48
, Issue.2
, pp. 225-242
-
-
Solis-Anez, E.1
Delgado-Luengo, W.2
Borjas-Fuentes, L.3
-
67
-
-
17344364660
-
Linkage-disequilibrium mapping of autistic disorder, with 15q11-13 markers
-
Cook EH Jr, Courchesne RY, Cox NJ, et al. Linkage-disequilibrium mapping of autistic disorder, with 15q11-13 markers. Am J Hum Genet 1998;62(5):1077-83
-
(1998)
Am J Hum Genet
, vol.62
, Issue.5
, pp. 1077-1083
-
-
Cook Jr, E.H.1
Courchesne, R.Y.2
Cox, N.J.3
-
68
-
-
85047700330
-
Association between a GABRB3 polymorphism and autism
-
Buxbaum JD, Silverman JM, Smith CJ, et al. Association between a GABRB3 polymorphism and autism. Mol Psychiatry 2002;7(3):311-6
-
(2002)
Mol Psychiatry
, vol.7
, Issue.3
, pp. 311-316
-
-
Buxbaum, J.D.1
Silverman, J.M.2
Smith, C.J.3
-
69
-
-
18344386200
-
Association analysis of chromosome 15 GABAA receptor subunit genes in autistic disorder
-
Menold MM, Shao Y, Wolpert CM, et al. Association analysis of chromosome 15 GABAA receptor subunit genes in autistic disorder. J Neurogenet 2001;15(3-4):245-59
-
(2001)
J Neurogenet
, vol.15
, Issue.3-4
, pp. 245-259
-
-
Menold, M.M.1
Shao, Y.2
Wolpert, C.M.3
-
70
-
-
0037371673
-
Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes
-
Shao Y, Cuccaro ML, Hauser ER, et al. Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes. Am J Hum Genet 2003;72(3):539-48
-
(2003)
Am J Hum Genet
, vol.72
, Issue.3
, pp. 539-548
-
-
Shao, Y.1
Cuccaro, M.L.2
Hauser, E.R.3
-
71
-
-
34249036179
-
3H]-Flunitrazepam-labeled benzodiazepine binding sites in the hippocampal formation in autism: A multiple concentration autoradiographic study
-
Guptill JT, Booker AB, Gibbs TT, et al. [3H]-Flunitrazepam-labeled benzodiazepine binding sites in the hippocampal formation in autism: a multiple concentration autoradiographic study. J Autism Dev Disord 2007;37(5):911-20
-
(2007)
J Autism Dev Disord
, vol.37
, Issue.5
, pp. 911-920
-
-
Guptill, J.T.1
Booker, A.B.2
Gibbs, T.T.3
-
72
-
-
33746491081
-
An association analysis of candidate genes on chromosome 15 q11-13 and autism spectrum disorder
-
Curran S, Powell J, Neale BM, et al. An association analysis of candidate genes on chromosome 15 q11-13 and autism spectrum disorder. Mol Psychiatry 2006;11(8):709-13
-
(2006)
Mol Psychiatry
, vol.11
, Issue.8
, pp. 709-713
-
-
Curran, S.1
Powell, J.2
Neale, B.M.3
-
73
-
-
0037108019
-
Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices
-
Fatemi SH, Halt AR, Stary JM, et al. Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices. Biol Psychiatry 2002;52(8):805-10
-
(2002)
Biol Psychiatry
, vol.52
, Issue.8
, pp. 805-810
-
-
Fatemi, S.H.1
Halt, A.R.2
Stary, J.M.3
-
74
-
-
34247631067
-
Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: Pathological implications
-
Yip J, Soghomonian J-J, Blatt GJ. Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathological implications. Acta Neuropathol 2007;113(5):559-68
-
(2007)
Acta Neuropathol
, vol.113
, Issue.5
, pp. 559-568
-
-
Yip, J.1
Soghomonian, J.-J.2
Blatt, G.J.3
-
76
-
-
0037296984
-
Plasma amino acid levels in children with autism and their families
-
Aldred S, Moore KM, Fitzgerald M, Waring RH. Plasma amino acid levels in children with autism and their families. J Autism Dev Disord 2003;33(1):93-7
-
(2003)
J Autism Dev Disord
, vol.33
, Issue.1
, pp. 93-97
-
-
Aldred, S.1
Moore, K.M.2
Fitzgerald, M.3
Waring, R.H.4
-
78
-
-
85047697869
-
In vivo 1H-magnetic resonance spectroscopy study of amygdala-hippocampal and parietal regions in autism
-
Page LA, Daly E, Schmitz N, et al. In vivo 1H-magnetic resonance spectroscopy study of amygdala-hippocampal and parietal regions in autism. Am J Psychiatry 2006;163:2189-92
-
(2006)
Am J Psychiatry
, vol.163
, pp. 2189-2192
-
-
Page, L.A.1
Daly, E.2
Schmitz, N.3
-
79
-
-
0031414052
-
Antiepileptic drug cellular mechanisms of action: Where does lamotrigine fit in?
-
Coulter DA. Antiepileptic drug cellular mechanisms of action: where does lamotrigine fit in? J Child Neurol 1997;12(Suppl 1):S2-9
-
(1997)
J Child Neurol
, vol.12
, Issue.SUPPL. 1
-
-
Coulter, D.A.1
-
80
-
-
0035321893
-
Lamotrigine therapy for autistic disorder: A randomized, double-blind, placebo-controlled trial
-
Belsito KM, Law PA, Kirk KS, et al. Lamotrigine therapy for autistic disorder: A randomized, double-blind, placebo-controlled trial. J Autism Dev Disord 2001;32(2):175-81
-
(2001)
J Autism Dev Disord
, vol.32
, Issue.2
, pp. 175-181
-
-
Belsito, K.M.1
Law, P.A.2
Kirk, K.S.3
-
81
-
-
14344267755
-
Double-blind, placebo-controlled study of amantadine hydrochloride in the treatment of children with autistic disorder
-
King BH, Wright DM, Handen BL, et al. Double-blind, placebo-controlled study of amantadine hydrochloride in the treatment of children with autistic disorder. J Am Acad Child Adolesc Psychiatry 2001;40(6):658-65
-
(2001)
J Am Acad Child Adolesc Psychiatry
, vol.40
, Issue.6
, pp. 658-665
-
-
King, B.H.1
Wright, D.M.2
Handen, B.L.3
-
82
-
-
33845509491
-
A placebo double-blind pilot study of dextromethorphan for problematic behaviours in children with autism
-
Woodward C, Groden J, Goodwin M, Bodfish J. A placebo double-blind pilot study of dextromethorphan for problematic behaviours in children with autism. Autism 2007;11(1):29-41
-
(2007)
Autism
, vol.11
, Issue.1
, pp. 29-41
-
-
Woodward, C.1
Groden, J.2
Goodwin, M.3
Bodfish, J.4
-
83
-
-
33645215436
-
Steinbusch HW, Autism: Neuropathology, alterations of the GABAergic system, and animal models
-
Schmitz C, Van Kooten IA, Hof PR, et al. Steinbusch HW, Autism: neuropathology, alterations of the GABAergic system, and animal models. Int Rev Neurobiol 2005;71:1-26
-
(2005)
Int Rev Neurobiol
, vol.71
, pp. 1-26
-
-
Schmitz, C.1
Van Kooten, I.A.2
Hof, P.R.3
-
84
-
-
38049013294
-
GARB3 gene deficient mice exhibit impaired social and exploratory behaviours, deficits in non-selective attention and hypoplasia of cebrellar vermal lobules: A potential model of autism spectrum disorder
-
Delorey TM, Sahbaie P, Hashemi E, et al. GARB3 gene deficient mice exhibit impaired social and exploratory behaviours, deficits in non-selective attention and hypoplasia of cebrellar vermal lobules: A potential model of autism spectrum disorder. Behav Brain Res 2008;187(2):207-20
-
(2008)
Behav Brain Res
, vol.187
, Issue.2
, pp. 207-220
-
-
Delorey, T.M.1
Sahbaie, P.2
Hashemi, E.3
-
85
-
-
0034692175
-
GABA-activated ligand gated ion channels: Medicinal chemistry and molecular biology
-
Chebib M, Johnston GAR. GABA-activated ligand gated ion channels: medicinal chemistry and molecular biology. J Med Chem 2000;43(8):1427-47
-
(2000)
J Med Chem
, vol.43
, Issue.8
, pp. 1427-1447
-
-
Chebib, M.1
Johnston, G.A.R.2
-
86
-
-
0142218355
-
The GABAA receptor gene family: New opportunities for drug development
-
Whiting PJ. The GABAA receptor gene family: New opportunities for drug development. Curr Opin Drug Discov Devel 2003;6(5):648-57
-
(2003)
Curr Opin Drug Discov Devel
, vol.6
, Issue.5
, pp. 648-657
-
-
Whiting, P.J.1
-
87
-
-
33750511497
-
GABAA receptors as targets for different classes of drugs
-
Sieghart W. GABAA receptors as targets for different classes of drugs. Drugs Future 2006;31(8):685-94
-
(2006)
Drugs Future
, vol.31
, Issue.8
, pp. 685-694
-
-
Sieghart, W.1
-
88
-
-
0023605732
-
Paradoxical reactions elicited by diazepam in children with classic autism
-
Marrosu G, Rachel MG, Biggio G. Paradoxical reactions elicited by diazepam in children with classic autism. Funct Neurol 1987;2(3):355-61
-
(1987)
Funct Neurol
, vol.2
, Issue.3
, pp. 355-361
-
-
Marrosu, G.1
Rachel, M.G.2
Biggio, G.3
-
89
-
-
33749236065
-
Topiramate in children with autistic spectrum disorders
-
Mazzone L, Ruta L. Topiramate in children with autistic spectrum disorders. Brain Dev 2006;28(10):688
-
(2006)
Brain Dev
, vol.28
, Issue.10
, pp. 688
-
-
Mazzone, L.1
Ruta, L.2
-
90
-
-
0029844153
-
Use of risperidone in pervasive developmental disorders: A case study
-
Fisman S, Steele M. Use of risperidone in pervasive developmental disorders: a case study. J Child Adolesc Psychopharmacol 1996;6(3):177-90
-
(1996)
J Child Adolesc Psychopharmacol
, vol.6
, Issue.3
, pp. 177-190
-
-
Fisman, S.1
Steele, M.2
-
91
-
-
4544311881
-
Dopamine and the regulation of cognition and attention
-
Nieoullon A. Dopamine and the regulation of cognition and attention. Prog Neurobiol 2002;571:1-31
-
(2002)
Prog Neurobiol
, vol.571
, pp. 1-31
-
-
Nieoullon, A.1
-
92
-
-
27644579119
-
Dopaminergic contribution to the regulation of emotional perception
-
Salgado-Pineda P, Delaveau P, Blin O, Nieoullon A. Dopaminergic contribution to the regulation of emotional perception. Clin Neuropharmacol 2005;28(5):228-37
-
(2005)
Clin Neuropharmacol
, vol.28
, Issue.5
, pp. 228-237
-
-
Salgado-Pineda, P.1
Delaveau, P.2
Blin, O.3
Nieoullon, A.4
-
93
-
-
0037042110
-
Investigation of two variants in the DOPA decarboxylase gene in patients with autism
-
Lauritsen MB, Børglum AD, Betancur C, et al. Investigation of two variants in the DOPA decarboxylase gene in patients with autism. Am J Med Genet 2002;114(4):466-70
-
(2002)
Am J Med Genet
, vol.114
, Issue.4
, pp. 466-470
-
-
Lauritsen, M.B.1
Børglum, A.D.2
Betancur, C.3
-
95
-
-
0027193007
-
effects of atypical antipsychotic agents on social behavior in rodents
-
Corbett R, Hartman H, Kerman LL, et al. effects of atypical antipsychotic agents on social behavior in rodents. Pharmacol Biochem Behav 1993;45(1):9-17
-
(1993)
Pharmacol Biochem Behav
, vol.45
, Issue.1
, pp. 9-17
-
-
Corbett, R.1
Hartman, H.2
Kerman, L.L.3
-
96
-
-
24944548298
-
Effects of dopaminergic and serotonergic manipulation on emotional processing: A pharmacological fMRI study
-
Takahashi H, Yahata N, Koeda M, et al. Effects of dopaminergic and serotonergic manipulation on emotional processing: a pharmacological fMRI study. Neuroimage 2005;27(4):991-1001
-
(2005)
Neuroimage
, vol.27
, Issue.4
, pp. 991-1001
-
-
Takahashi, H.1
Yahata, N.2
Koeda, M.3
-
97
-
-
33644875799
-
Effect of levodopa on healthy volunteers' facial emotion perception: An fMRI study
-
Delaveau P, Salgado-Pineda P, Wicker B, et al. Effect of levodopa on healthy volunteers' facial emotion perception: an fMRI study. Clin Neuropharmacol 2005;28(6):255-61
-
(2005)
Clin Neuropharmacol
, vol.28
, Issue.6
, pp. 255-261
-
-
Delaveau, P.1
Salgado-Pineda, P.2
Wicker, B.3
-
98
-
-
0036899894
-
Dextroampheramine modulates the response of the human amygdala
-
Hariri AR, Mattay VS, Tessitore A, et al. Dextroampheramine modulates the response of the human amygdala. Neuropsychopharmacology 2002;27(6):1036-40
-
(2002)
Neuropsychopharmacology
, vol.27
, Issue.6
, pp. 1036-1040
-
-
Hariri, A.R.1
Mattay, V.S.2
Tessitore, A.3
-
99
-
-
0032565597
-
Risperidone versus haloperidol for perception of emotion in treatment-resistant schizophrenia: Preliminary findings
-
Kee KS, Kern RS, Marshall Jr BD, Green Mf. Risperidone versus haloperidol for perception of emotion in treatment-resistant schizophrenia: preliminary findings. Schizophr Res 1998;31(2-3):159-65
-
(1998)
Schizophr Res
, vol.31
, Issue.2-3
, pp. 159-165
-
-
Kee, K.S.1
Kern, R.S.2
Marshall Jr, B.D.3
Green, M.4
-
100
-
-
0023190318
-
CSF monoamines in autistic syndromes and other pervasive developmental disorders of early childhood
-
Gillberg C. Svennerholm L CSF monoamines in autistic syndromes and other pervasive developmental disorders of early childhood. Br J Psychiatry 1987;151:89-94
-
(1987)
Br J Psychiatry
, vol.151
, pp. 89-94
-
-
Gillberg, C.1
Svennerholm, L.2
-
102
-
-
0026655498
-
Plasma and urinary levels of biopterin, neopterin, and related pterins and plasma levels of folate in infantile autism
-
Eto I, Bandy MD, Butterworth CE Jr. Plasma and urinary levels of biopterin, neopterin, and related pterins and plasma levels of folate in infantile autism. J Autism Dev Disord 1992;22(2):295-308
-
(1992)
J Autism Dev Disord
, vol.22
, Issue.2
, pp. 295-308
-
-
Eto, I.1
Bandy, M.D.2
Butterworth Jr., C.E.3
-
103
-
-
0028171290
-
-
Tani Y, Fernell E, Watanabe Y, et al. Decrease in 6R-5,6,7,8-tetrahydrobiopterin content in cerebrospinal fluid of autistic patients. Neurosci Lett 1994;181(1-2):169-72
-
Tani Y, Fernell E, Watanabe Y, et al. Decrease in 6R-5,6,7,8-tetrahydrobiopterin content in cerebrospinal fluid of autistic patients. Neurosci Lett 1994;181(1-2):169-72
-
-
-
-
104
-
-
0029068833
-
Cerebrospinal fluid biopterin and biogenic amine metabolites during oral R-THBP therapy for infantile autism
-
Komori H, Matsuishi T, Yamada S, et al. Cerebrospinal fluid biopterin and biogenic amine metabolites during oral R-THBP therapy for infantile autism. J Autism Dev Disord 1995;25(2):183-93
-
(1995)
J Autism Dev Disord
, vol.25
, Issue.2
, pp. 183-193
-
-
Komori, H.1
Matsuishi, T.2
Yamada, S.3
-
105
-
-
8544278907
-
Possible effects of tetrahydrobiopterin treatment in six children with autism-clinical and positron emission tomography data: A pilot study
-
Fernell E, Watanabe Y, Adolfsson I, et al. Possible effects of tetrahydrobiopterin treatment in six children with autism-clinical and positron emission tomography data: a pilot study. Dev Med Child Neurol 1997;39(5):313-8
-
(1997)
Dev Med Child Neurol
, vol.39
, Issue.5
, pp. 313-318
-
-
Fernell, E.1
Watanabe, Y.2
Adolfsson, I.3
-
106
-
-
0342601394
-
Low medial prefrontal dopaminergic activity in autistic children
-
Ernst M, Zametkin AJ, Matochik JA, et al. Low medial prefrontal dopaminergic activity in autistic children. Lancet 1997;350(9078):638
-
(1997)
Lancet
, vol.350
, Issue.9078
, pp. 638
-
-
Ernst, M.1
Zametkin, A.J.2
Matochik, J.A.3
-
107
-
-
33846643952
-
Positive effects of methylphenidate on inattention and hyperactivity in pervasive developmental disorders: An analysis of secondary measures
-
Posey DJ, Aman MG, McCracken JT, et al. Positive effects of methylphenidate on inattention and hyperactivity in pervasive developmental disorders: an analysis of secondary measures. Biol Psychiatry 2007;61(4):538-44
-
(2007)
Biol Psychiatry
, vol.61
, Issue.4
, pp. 538-544
-
-
Posey, D.J.1
Aman, M.G.2
McCracken, J.T.3
-
108
-
-
27744466024
-
Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity
-
Posey DJ, Aman MG, Arnold LE, et al. Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity. Arch Gen Psychiatry 2005;62(11):1266-74
-
(2005)
Arch Gen Psychiatry
, vol.62
, Issue.11
, pp. 1266-1274
-
-
Posey, D.J.1
Aman, M.G.2
Arnold, L.E.3
-
109
-
-
0033798312
-
-
Handen BL, Johnson CR. Lubetsky M Efficacy of methylphenidate among children with autism and symptoms of attention-deficit hyperactivity disorder. J Autism Dev Disord 2000;30(3):245-55
-
Handen BL, Johnson CR. Lubetsky M Efficacy of methylphenidate among children with autism and symptoms of attention-deficit hyperactivity disorder. J Autism Dev Disord 2000;30(3):245-55
-
-
-
-
110
-
-
0028998160
-
Use of methylphenidate in the treatment of children with autistic disorder
-
Quintana H, Birmaher B, Stedge D, et al. Use of methylphenidate in the treatment of children with autistic disorder. J Autism Dev Disord 1995;25(3):283-94
-
(1995)
J Autism Dev Disord
, vol.25
, Issue.3
, pp. 283-294
-
-
Quintana, H.1
Birmaher, B.2
Stedge, D.3
-
111
-
-
33750203500
-
Atomoxetine treating patients with autistic disorder
-
Niederhofer H, Damodharan SK, Joji R, Corfield A. Atomoxetine treating patients with autistic disorder. Autism 2006;10(6):646-9
-
(2006)
Autism
, vol.10
, Issue.6
, pp. 646-649
-
-
Niederhofer, H.1
Damodharan, S.K.2
Joji, R.3
Corfield, A.4
-
112
-
-
33749053222
-
Atomoxetine for hyperactivity in autism spectrum disorders: Placebo-controlled crossover pilot trial
-
Arnold LE, Aman MG, Cook AM, et al. Atomoxetine for hyperactivity in autism spectrum disorders: placebo-controlled crossover pilot trial. J Am Acad Child Adolesc Psychiatry 2006;45(10):1196-205
-
(2006)
J Am Acad Child Adolesc Psychiatry
, vol.45
, Issue.10
, pp. 1196-1205
-
-
Arnold, L.E.1
Aman, M.G.2
Cook, A.M.3
-
113
-
-
33646152528
-
A dopaminergic deficit hypothesis of schizophrenia: The path to discovery
-
Carlsson A, Carlsson ML. A dopaminergic deficit hypothesis of schizophrenia: the path to discovery. Dialogues Clin Neurosci 2006;8(1):137-42
-
(2006)
Dialogues Clin Neurosci
, vol.8
, Issue.1
, pp. 137-142
-
-
Carlsson, A.1
Carlsson, M.L.2
-
114
-
-
1642283136
-
Dopamine partial agonists: A new class of antipsychotic
-
Lieberman JA. Dopamine partial agonists: a new class of antipsychotic. CNS Drugs 2004;14(4):251-67
-
(2004)
CNS Drugs
, vol.14
, Issue.4
, pp. 251-267
-
-
Lieberman, J.A.1
-
115
-
-
0027934781
-
Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: Synthesis and structure-activity relationships
-
Sonesson C, Lin C-H, Hansson L, et al. Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: synthesis and structure-activity relationships. J Med Chem 1994;37(17):2735-53
-
(1994)
J Med Chem
, vol.37
, Issue.17
, pp. 2735-2753
-
-
Sonesson, C.1
Lin, C.-H.2
Hansson, L.3
-
116
-
-
33745933839
-
The dopamine stabilizers (S)-(-)-(3-Methanesulfonyl-phenyl)-1-propyl-piperidine [(-)-OSU6162] and 4-(3-Methanesulfonylphenyl)-1-propyl-piperidine (ACR16) show high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor side effects in the rat
-
Natesan S, Svensson KA, Reckless GE, et al. The dopamine stabilizers (S)-(-)-(3-Methanesulfonyl-phenyl)-1-propyl-piperidine [(-)-OSU6162] and 4-(3-Methanesulfonylphenyl)-1-propyl-piperidine (ACR16) show high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor side effects in the rat. J Pharmacol Exp Ther 2006;318(2):818-9
-
(2006)
J Pharmacol Exp Ther
, vol.318
, Issue.2
, pp. 818-819
-
-
Natesan, S.1
Svensson, K.A.2
Reckless, G.E.3
-
117
-
-
0027097565
-
Distinct promoters direct neuronal and nonneuronal expression of rat aromatic L-amino acid decarboxylase
-
Albert VR, Lee MR, Bolden AH, et al. Distinct promoters direct neuronal and nonneuronal expression of rat aromatic L-amino acid decarboxylase. Proc Natl Acad Sci USA 1992;89(24):12053-7
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, Issue.24
, pp. 12053-12057
-
-
Albert, V.R.1
Lee, M.R.2
Bolden, A.H.3
-
118
-
-
4644289667
-
Identification and characterization of a novel form of the human L-dopa decarboxylase mRNA
-
Vassilacopoulou D, Sideris DC, Vassiliou AG, Fragoulis EG. Identification and characterization of a novel form of the human L-dopa decarboxylase mRNA. Neurochem Res 2004;29(10):1817-23
-
(2004)
Neurochem Res
, vol.29
, Issue.10
, pp. 1817-1823
-
-
Vassilacopoulou, D.1
Sideris, D.C.2
Vassiliou, A.G.3
Fragoulis, E.G.4
-
119
-
-
0030052818
-
Alternative splicing in the coding region of human aromatic L-amino acid decarboxylase mRNA
-
Chang YT, Mues G, Hyland H. Alternative splicing in the coding region of human aromatic L-amino acid decarboxylase mRNA. Neurosci Lett 1996;202(3):157-60
-
(1996)
Neurosci Lett
, vol.202
, Issue.3
, pp. 157-160
-
-
Chang, Y.T.1
Mues, G.2
Hyland, H.3
-
120
-
-
0028840928
-
The human aromatic L-amino acid decarboxylase gene can be alternatively spliced to generate unique protein isoforms
-
O'Malley KL, Harmon S, Moffat M, et al. The human aromatic L-amino acid decarboxylase gene can be alternatively spliced to generate unique protein isoforms. J Neurochem 1995;65(6):2409-16
-
(1995)
J Neurochem
, vol.65
, Issue.6
, pp. 2409-2416
-
-
O'Malley, K.L.1
Harmon, S.2
Moffat, M.3
-
121
-
-
0026439089
-
Tissue specific alternative splicing of the first exon generates two types of mRNAs in human aromatic L-amino acid decarboxylase
-
Ichinose H, Sumi-Ichinose C, Ohye T, et al. Tissue specific alternative splicing of the first exon generates two types of mRNAs in human aromatic L-amino acid decarboxylase. Biochemistry 1992;31(46):11546-50
-
(1992)
Biochemistry
, vol.31
, Issue.46
, pp. 11546-11550
-
-
Ichinose, H.1
Sumi-Ichinose, C.2
Ohye, T.3
-
122
-
-
1242293704
-
Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats
-
Watanabe Y, Hashimoto S, Kakita A, et al. Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats. Neurosci Res 2004;48(3):345-53
-
(2004)
Neurosci Res
, vol.48
, Issue.3
, pp. 345-353
-
-
Watanabe, Y.1
Hashimoto, S.2
Kakita, A.3
-
123
-
-
0038303560
-
Low prevalence of smoking in patients with autistic spectrum disorders
-
Bejerot S, Nylander L. Low prevalence of smoking in patients with autistic spectrum disorders. Psychiatry Res 2003;119(2):177-82
-
(2003)
Psychiatry Res
, vol.119
, Issue.2
, pp. 177-182
-
-
Bejerot, S.1
Nylander, L.2
-
124
-
-
0034946403
-
Cholinergic activity in autism: Abnormalities in the cerebral cortex and basal forebrain
-
Perry EK, Lee MLW, Martin-Ruiz CM, et al. Cholinergic activity in autism: Abnormalities in the cerebral cortex and basal forebrain. Am J Psychiatry 2001;158(7):1058-66
-
(2001)
Am J Psychiatry
, vol.158
, Issue.7
, pp. 1058-1066
-
-
Perry, E.K.1
Lee, M.L.W.2
Martin-Ruiz, C.M.3
-
125
-
-
0036310086
-
Nicotinic receptor abnormalities in the cerebellar cortex in autism
-
Lee M, Martin-Ruiz C, Graham A, et al. Nicotinic receptor abnormalities in the cerebellar cortex in autism. Brain 2002;125(7):1483-95
-
(2002)
Brain
, vol.125
, Issue.7
, pp. 1483-1495
-
-
Lee, M.1
Martin-Ruiz, C.2
Graham, A.3
-
126
-
-
22044434861
-
Neuronal nicotinic receptor subunits in autism: An immunohistochemical investigation in the thalamus
-
Ray MA, Graham AJ, Lee M, et al. Neuronal nicotinic receptor subunits in autism: An immunohistochemical investigation in the thalamus. Neurobiol Dis 2005;19(3):366-77
-
(2005)
Neurobiol Dis
, vol.19
, Issue.3
, pp. 366-377
-
-
Ray, M.A.1
Graham, A.J.2
Lee, M.3
-
127
-
-
33750960154
-
A prospective, open-label trial of galantamine in autistic disorder
-
Nicolson R, Craven-Thuss B, Smith J. A prospective, open-label trial of galantamine in autistic disorder. J Child Adole Psychopharm 2006;16(5):621-9
-
(2006)
J Child Adole Psychopharm
, vol.16
, Issue.5
, pp. 621-629
-
-
Nicolson, R.1
Craven-Thuss, B.2
Smith, J.3
-
128
-
-
2342436849
-
Treating autistic spectrum disorders in children: Utility of the cholinesterase inhibitor rivastigmine tartrate
-
Chez MG, Aimonovitch M, Buchanan T, et al. Treating autistic spectrum disorders in children: Utility of the cholinesterase inhibitor rivastigmine tartrate. J Child Neurol 2004;19(3):165-9
-
(2004)
J Child Neurol
, vol.19
, Issue.3
, pp. 165-169
-
-
Chez, M.G.1
Aimonovitch, M.2
Buchanan, T.3
-
129
-
-
0000140208
-
Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): An orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties
-
Lin N-H, Gunn DE, Ryther KB, et al. Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): An orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties. J Med Chem 1997;40(3):385-90
-
(1997)
J Med Chem
, vol.40
, Issue.3
, pp. 385-390
-
-
Lin, N.-H.1
Gunn, D.E.2
Ryther, K.B.3
-
130
-
-
0030426707
-
-
Bencherif M, Lovette ME, Fowler KW, et al. RJR-2403: a nicotinic agonist with CNS selectivity I. In vitro characterization. J Pharmacol Exp Ther 1996;279(3):1413-21
-
Bencherif M, Lovette ME, Fowler KW, et al. RJR-2403: a nicotinic agonist with CNS selectivity I. In vitro characterization. J Pharmacol Exp Ther 1996;279(3):1413-21
-
-
-
-
131
-
-
0030439041
-
-
Lippiello PM, Bencherif M, Gray JA, et al. RJR-2403, A nicotinic agonist with CNS selectivity II. In vivo characterization. J Pharmacol Exp Ther 1996;279(3):1422-9
-
Lippiello PM, Bencherif M, Gray JA, et al. RJR-2403, A nicotinic agonist with CNS selectivity II. In vivo characterization. J Pharmacol Exp Ther 1996;279(3):1422-9
-
-
-
-
132
-
-
48449095750
-
-
AZD3480 (TC-1734) - Cognitive impairment, including Alzheimer's disease and cognitive dysfunction in schizophrenia. Available from: www.targacept.com/wt/page/tc_1734 [Last accessed 12 May 2008]
-
AZD3480 (TC-1734) - Cognitive impairment, including Alzheimer's disease and cognitive dysfunction in schizophrenia. Available from: www.targacept.com/wt/page/tc_1734 [Last accessed 12 May 2008]
-
-
-
-
133
-
-
0038002920
-
SSR591813, a novel selective and partial (4(2 nicotinic receptor agonist with potential as an aid to smoking cessation
-
Cohen C, Bergis OE, Galli F, et al. SSR591813, a novel selective and partial (4(2 nicotinic receptor agonist with potential as an aid to smoking cessation. J Pharmacol Exp Ther 2003;306(1):407-20
-
(2003)
J Pharmacol Exp Ther
, vol.306
, Issue.1
, pp. 407-420
-
-
Cohen, C.1
Bergis, O.E.2
Galli, F.3
|