Receptor technology-cell binding to P-15: A new method of regenerating bone quickly and safely-preliminary histomorphometrical and mechanical results in sinus floor augmentations

Keio Journal of Medicine

Volumn 53, Issue 3, 2004, Pages 166-171

  Valentin, Andreas H ^a,b   Weber, J ^c  

^a Institute for Oral Surgery   (Germany)

^b NIPPON DENTAL UNIVERSITY   (Japan)

^c Sirona Dental Systems GmbH   (Germany)

Author keywords

Biomimetic environment; Osteogenic differentiation; Receptor engineering

Indexed keywords

BIOMATERIAL; COLLAGEN TYPE 1; SCLEROPROTEIN;

ADULT; AGED; BONE DEVELOPMENT; BONE REGENERATION; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; HUMAN; IMPLANT; MATERIALS; MORPHOMETRICS; OSTEOBLAST; PARANASAL SINUS; PROTEIN BINDING; PROTEIN DOMAIN; RECEPTOR BINDING; REVIEW; STEM CELL; TECHNOLOGY; TISSUE ENGINEERING;

ADULT; AGED; BONE DISEASES; BONE REGENERATION; BONE SUBSTITUTES; HUMANS; MAXILLARY SINUS;

EID: 4844227766     PISSN: 00229717     EISSN: None     Source Type: Journal    
DOI: 10.2302/kjm.53.166     Document Type: Review

References (16)

1. Ducy P, Schinke T, Karsenty G: The osteoblast: a sophisticated fibroblast under central surveillance. Science 2000; 289: 1501-1504
2. Bhatnagar RS, Qian JJ, Wedrychowska A, Sadeghi M, Wu YM, Smith N: Design of biomimetic habitats for tissue engineering with P-15, a synthetic peptide analogue of collagen. Tissue Eng 1999; 5: 53-65
3. Bhatnagar RS, Qian JJ, Gough CA: The role in cell binding of a beta-bend within the triple helical region in collagen alpha 1 (I) chain: structural and biological evidence for conformational tautomerism on fiber surface. J Biomol Struct Dyn 1997; 14: 547-560
4. Sastry SK, Horwitz AF: Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling. Curr Opin Cell Biol 1993; 5: 819-831
5. Bhatnagar RS, Qian JJ, Gough CA: The role in cell binding of a beta-bend within the triple helical region in collagen alpha 1 (I) chain: structural and biological evidence for conformational tautomerism on fiber surface. J Biomol Struct Dyn 1997; 14: 547-560
6. Turhani D, et al: Osteocalcinexpression in "Tissue Engineering" hergestellten Biokomposits. Z Zahnärztliche Impl 2003; 19: 153-158
7. Yukna RA, Callan DP, Krauser JT, Evans GH, Aichelmann-Reidy ME, Moore K, Cruz R, Scott JB: Multi-center clinical evaluation of combination anorganic bovine-derived hydroxyapatite matrix (ABM)/cell binding peptide (P-15) as a bone replacement graft material in human periodontal osseous defects. 6-month results. J Periodontol 1998; 69: 655-663
8. Yukna RA, Krauser JT, Callan DP, Evans GH, Cruz R, Martin M: Multi-center clinical comparison of combination anorganic bovine-derived hydroxyapatite matrix (ABM)/cell binding peptide (P-15) and ABM in human periodontal osseous defects. 6-month results. J Periodontol 2000; 71: 1671-1679
9. Krauser JT, Rohrer MD, Wallace SS: Human histologic and histomorphometric analysis comparing OsteoGraf/N with PepGen P-15 in the maxillary sinus elevation procedure: a case report. Implant Dent 2000; 9: 298-302
10. Wheeler SL, Holmes RE, Calhoun CJ: Six-year clinical and histologic study of sinus-lift grafts. Int J Oral Maxillofac Implants 1996; 11: 26-34
11. Sartori S, Silvestri M, Forni F, Icaro Cornaglia A, Tesei P, Cattaneo V: Ten-year follow-up in a maxillary sinus augmentation using anorganic bovine bone (Bio-Oss). A case report with histomorphometric evaluation. Clin Oral Implants Res 2003; 14: 369-372
12. Urist MR: Bone: formation by autoinduction. Science 1965; 150: 893-899
13. Urist MR, Mikulski A, Lietze A: Solubilized and insolubilized bone morphogenetic protein. Proc Natl Acad Sci USA 1979; 76: 1828-1832
14. Qian JJ, Bhatnagar RS: Enhanced cell attachment to anorganic bone mineral in the presence of a synthetic peptide related to collagen. J Biomed Mater Res 1996; 31: 545-554
15. Bhatnagar R, Qian JJ, Wedrychowsa A, Smith N: Construction of biomimetic environments with a synthetic peptide analogue of collagen. Material Research Society Symp Proc 1998; v. 530
16. Krauser JT, Rohrer MD, Wallace SS: Human histologic and histomorphometric analysis comparing OsteoGraf/N with PepGen P-15 in the maxillary sinus elevation procedure: a case report. Implant Dent 2000; 9: 298-302