Evaluation of multiplexed CE with UV detection for rapid pKa estimation of active pharmaceutical ingredients

Chromatographia

Volumn 68, Issue 3-4, 2008, Pages 219-225

  Gong, Xiaoyi ^a   Figus, Margaret ^a   Plewa, Jolanta ^a   Levorse, Dorothy A ^a   Zhou, Lili ^a   Welch, Christopher J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Acid dissociation constant; Capillary electrophoresis; UV detection

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENT; DIMETHYL SULFOXIDE; DRUG ANALOG; METHANOL; REAGENT; SOLVENT;

ACCURACY; ARTICLE; CAPILLARY ELECTROPHORESIS; DISSOCIATION CONSTANT; DRUG DETERMINATION; DRUG FORMULATION; DRUG IMPURITY; DRUG MANUFACTURE; DRUG PURITY; DRUG RESEARCH; DRUG SOLUBILITY; DRUG STRUCTURE; PRIORITY JOURNAL; ULTRAVIOLET RADIATION;

EID: 48349117828     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1365/s10337-008-0691-6     Document Type: Article

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