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The constant structural motif in the iridal series is the central six-membered B-ring, incorporating two adjacent quaternary centers at C10, C11. The same ring system, albeit with different locations of unsaturation and oxygen functionality, is found in a great number of related molecules.
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The constant structural motif in the iridal series is the central six-membered B-ring, incorporating two adjacent quaternary centers at C10, C11. The same ring system, albeit with different locations of unsaturation and oxygen functionality, is found in a great number of related molecules.
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58149184491
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Both quaternary stereogenic centers are obtained as required; no stereoisomer formation was detected
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Both quaternary stereogenic centers are obtained as required; no stereoisomer formation was detected.
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19
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0011980555
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For the original procedure (reduction of acrylonitriles) see: Profitt, J. A.; Watt, D. S.; Corey, E. J. J. Org. Chem. 1975, 40, 127. Adapted to α,ß,-unsaturated esters by: Hudlicky, T.; Sinai-Zingde, G.; Natchus, M. G. Tetrahedron Lett. 1987, 28, 5287-5290.
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For the original procedure (reduction of acrylonitriles) see: Profitt, J. A.; Watt, D. S.; Corey, E. J. J. Org. Chem. 1975, 40, 127. Adapted to α,ß,-unsaturated esters by: Hudlicky, T.; Sinai-Zingde, G.; Natchus, M. G. Tetrahedron Lett. 1987, 28, 5287-5290.
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0036545581
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7.2 E double bond are known: Takahashi, K.; Suzuki, S.; Hano. Y.; Nomura, T. Biol. Pharm. Bull. 2002, 25, 432-436.
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7.2 E double bond are known: Takahashi, K.; Suzuki, S.; Hano. Y.; Nomura, T. Biol. Pharm. Bull. 2002, 25, 432-436.
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