Sequence Verification of Oligonucleotides Containing Multiple Arylamine Modifications by Enzymatic Digestion and Liquid Chromatography Mass Spectrometry (LC/MS)

Journal of the American Society for Mass Spectrometry

Volumn 19, Issue 8, 2008, Pages 1147-1155

  Gao, Lan ^a   Zhang, Li ^b   Cho, Bongsup P ^b   Chiarelli, M Paul ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; NUCLEIC ACIDS; OLIGONUCLEOTIDES; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; SULFUR COMPOUNDS;

AMERICAN SOCIETY; AMINOFLUORENE; ANALYTICAL METHODS; ARYL AMINES; ARYL-AMINES; ENZYMATIC DIGESTIONS; EXONUCLEASE; LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY (LC/MS); OLIGO NUCLEOTIDES; SITE SPECIFIC MUTAGENESIS; TRIFLUOROACETYL;

NUCLEOTIDES;

AROMATIC AMINE; ENDONUCLEASE; EXODEOXYRIBONUCLEASE III; EXODEOXYRIBONUCLEASE V; EXONUCLEASE; N ACETOXY N (2 FLUORENYL)ACETAMIDE; N ACETOXY N TRIFLUOROACETYL 2 AMINOFLUORENE; OLIGONUCLEOTIDE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR WEIGHT; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; ULTRAVIOLET SPECTROSCOPY;

AMINES; CHROMATOGRAPHY, LIQUID; ENDONUCLEASES; ESCHERICHIA COLI; EXONUCLEASES; HYDROLYSIS; ISOMERISM; OLIGONUCLEOTIDES; SEQUENCE ANALYSIS, DNA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 48349085387     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2008.04.034     Document Type: Article

References (24)

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