Transient middle cerebral artery occlusion induces microglial priming in the lumbar spinal cord: A novel model of neuroinflammation

Journal of Neuroinflammation

Volumn 5, Issue , 2008, Pages

  Moisse, Katie ^a,b   Welch, Ian ^b   Hill, Tracy ^b   Volkening, Kathryn ^a   Strong, Michael J ^a,b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

POLYLYSINE; SUTURE MATERIAL;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BRAIN ISCHEMIA; BRAIN NECROSIS; CAROTID ARTERY LIGATION; CELL ACTIVATION; CONTROLLED STUDY; DISEASE MODEL; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LUMBAR SPINAL CORD; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOTOR CORTEX; MOTOR NEURON DISEASE; MOUSE; NERVE DEGENERATION; NONHUMAN; REPERFUSION; REPRODUCIBILITY; SPINAL CORD NERVE CELL; SURVIVAL RATE; ANIMAL; BIOLOGICAL MODEL; BODY POSTURE; C57BL MOUSE; CEREBRAL ARTERY DISEASE; HEMISPHERIC DOMINANCE; INFLAMMATION; MIDDLE CEREBRAL ARTERY; MOTOR ACTIVITY; PATHOPHYSIOLOGY; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PHYSIOLOGY; SPINAL CORD;

ANIMALS; ARTERIAL OCCLUSIVE DISEASES; BRAIN ISCHEMIA; CEREBRAL ARTERIAL DISEASES; DISEASE MODELS, ANIMAL; FEMALE; FUNCTIONAL LATERALITY; INFLAMMATION; MICE; MICE, INBRED C57BL; MICROGLIA; MIDDLE CEREBRAL ARTERY; MODELS, BIOLOGICAL; MOTOR ACTIVITY; MOTOR NEURON DISEASE; POSTURE; REPERFUSION; SPINAL CORD;

EID: 48249154193     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-5-29     Document Type: Article

References (31)

1. Ince PG Shaw PJ Slade JY Jones C Hudgson P Familial amyotrophic lateral sclerosis with a mutation in exon 4 of the Cu/Zn superoxide dismutase gene: Pathological and immunocytochemical changes Acta Neuropathol (Berl) 1996, 92:395-403 10.1007/s004010050535
2. Turner MR Cagnin A Turkheimer FE Miller CC Shaw CE Brooks DJ Leigh PN Banati RB Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: An [11C](R)-PK11195 positron emission tomography study Neurobiol Dis 2004, 15:601-609 10.1016/ j.nbd.2003.12.012 15056468
3. Kriz J Nguyen MD Julien JP Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis Neurobiol Dis 2002, 10:268-278 10.1006/nbdi.2002.0487 12270689
4. Kriz J Gowing G Julien JP Efficient three-drug cocktail for disease induced by mutant superoxide dismutase Ann Neurol 2003, 53:429-436 10.1002/ana.10500 12666110
5. Zhang W Narayanan M Friedlander RM Additive neuroprotective effects of minocycline with creatine in a mouse model of ALS Ann Neurol 2003, 53:267-270 10.1002/ana.10476 12557297
6. van den Bosch L Tilkin P Lemmens G Robberecht W Minocycline delays disease onset and mortality in a transgenic model of ALS. Neuroreport 2002, 13:1067-1070 10.1097/00001756-200206120-00018 12060810
7. He BP Wen W Strong MJ Activated microglia (BV-2) facilitation of TNF - mediated motor neuron death in vitro J Neuroimmunol 2002, 128:31-38 10.1016/S0165-5728(02)00141-8 12098508
8. Weydt P Yuen EC Ransom BR Moller T Increased cytotoxic potential of microglia from ALS-transgenic mice Glia 2004, 48:179-182 10.1002/ glia.20062 15378658
9. Beers DR Henkel JS Xiao Q Zhao W Wang J Yen AA Siklos L McKercher SR Appel SH Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis Proc Natl Acad Sci U S A 2006, 103:16021-16026 1613228 17043238 10.1073/pnas.0607423103
10. Xiao Q Zhao W Beers DR Yen AA Xie W Henkel JS Appel SH Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia J Neurochem 2007, 102:2008-2019 10.1111/j.1471-4159.2007.04677.x 17555556
11. Perry VH The influence of systemic inflammation on inflammation in the brain: Implications for chronic neurodegenerative disease Brain Behav Immun 2004, 18:407-413 10.1016/j.bbi.2004.01.004 15265532
12. Moisse K Strong MJ Innate immunity in amyotrophic lateral sclerosis Biochim Biophys Acta 2006 16624536
13. Longa EZ Weinstein PR Carlson S Cummins R Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 1989, 20:84-91 2643202
14. Clark WM Lessov NS Dixon MP Eckenstein F Monofilament intraluminal middle cerebral artery occlusion in the mouse Neurol Res 1997, 19:641-648 9427967
15. Kitagawa K Matsumoto M Yang G Mabuchi T Yagita Y Hori M Yanagihara T Cerebral ischemia after bilateral carotid artery occlusion and intraluminal suture occlusion in mice: Evaluation of the patency of the posterior communicating artery J Cereb Blood Flow Metab 1998, 18:570-579 10.1097/00004647-199805000-00012 9591849
16. Belayev L Alonso OF Busto R Zhao W Ginsberg MD Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model Stroke 1996, 27:1616-1622 8784138
17. Belayev L Busto R Zhao W Fernandez G Ginsberg MD Middle cerebral artery occlusion in the mouse by intraluminal suture coated with poly-L-lysine: neurological and histological validation Brain Res 1999, 833:181-190 10.1016/S0006-8993(99)01528-0 10375693
18. Huang J Kim LJ Poisik A Pinsky DJ Connolly ES Jr. Titration of postischemic cerebral hypoperfusion by variation of ischemic severity in a murine model of stroke Neurosurgery 1999, 45:328-333 10.1097/ 00006123-199908000-00027 10449078
19. Connolly ES Jr. Winfree CJ Stern DM Solomon RA Pinsky DJ Procedural and strain-related variables significantly affect outcome in a murine model of focal cerebral ischemia Neurosurgery 1996, 38:523-531 10.1097/ 00006123-199603000-00021 8837805
20. Wu YP Ling EA Transsynaptic changes of neurons and associated microglial reaction in the spinal cord of rats following middle cerebral artery occlusion Neurosci Lett 1998, 256:41-44 10.1016/S0304-3940(98)00750-2 9832212
21. Fu D Ng YK Gan P Ling EA Permanent occlusion of the middle cerebral artery upregulates expression of cytokines and neuronal nitric oxide synthase in the spinal cord and urinary bladder in the adult rat Neuroscience 2004, 125:819-831 10.1016/j.neuroscience.2004.02.012 15120843
22. Wu YP Ling EA Induction of microglial and astrocytic response in the adult rat lumbar spinal cord following middle cerebral artery occlusion Exp Brain Res 1998, 118:235-242 10.1007/s002210050277 9547093
23. Wu YP Tan CK Ling EA Expression of Fos-like immunoreactivity in the brain and spinal cord of rats following middle cerebral artery occlusion Exp Brain Res 1997, 115:129-136 10.1007/PL00005672 9224840
24. Bederson JB Pitts LH Tsuji M Nishimura MC Davis RL Bartkowski H Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination Stroke 1986, 17:472-476 3715945
25. De RM Van RJ Borgers M Wauquier A Janssen PA Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats Stroke 1989, 20:1383-1390 2799870
26. Yang GY Betz AL Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in rats Stroke 1994, 25:1658-1664 8042219
27. Kuang RZ Kalil K Branching patterns of corticospinal axon arbors in the rodent J Comp Neurol 1990, 292:585-598 10.1002/cne.902920408 2324314
28. Liang FY Moret V Wiesendanger M Rouiller EM Corticomotoneuronal connections in the rat: Evidence from double-labeling of motoneurons and corticospinal axon arborizations J Comp Neurol 1991, 311:356-366 10.1002/ cne.903110306 1720143
29. Hossmann KA Glutamate-mediated injury in focal cerebral ischemia: The excitotoxin hypothesis revised Brain Pathol 1994, 4:23-36 7912980
30. Meldrum B Garthwaite J Excitatory amino acid neurotoxicity and neurodegenerative disease Trends Pharmacol Sci 1990, 11:379-387 10.1016/ 0165-6147(90)90184-A 2238094
31. Banati RB Gehrmann J Schubert P Kreutzberg GW Cytotoxicity of microglia Glia 1993, 7:111-118 10.1002/glia.440070117 8423058