Cardiac conduction disturbances and ventricular tachycardia after prolonged propofol infusion in an infant

PACE - Pacing and Clinical Electrophysiology

Volumn 31, Issue 8, 2008, Pages 1070-1073

  Robinson, Joshua D C ^a,b   Melman, Yonathan ^a,b   Walsh, Edward P ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Arrhythmia; Conduction disturbance; Propofol

Indexed keywords

PROPOFOL;

ANAMNESIS; ARTICLE; BRUGADA SYNDROME; CASE REPORT; DIAGNOSTIC IMAGING; ELECTROCARDIOGRAM; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CONDUCTION DISTURBANCE; HEART VENTRICLE TACHYCARDIA; HUMAN; INFANT; LABORATORY TEST; MALE; ST SEGMENT ELEVATION;

ANESTHETICS, INTRAVENOUS; BRUGADA SYNDROME; DIAGNOSIS, DIFFERENTIAL; HUMANS; INFANT; INFUSIONS, INTRAVENOUS; MALE; PROPOFOL; TACHYCARDIA, VENTRICULAR;

EID: 48249150359     PISSN: 01478389     EISSN: 15408159     Source Type: Journal    
DOI: 10.1111/j.1540-8159.2008.01138.x     Document Type: Article

References (15)

1. Lavoie J, Walsh EP, Burrows FA, Laussen P, Lulu JA, Hansen DD. Effects of propofol or isoflurane anesthesia on cardiac conduction in children undergoing radiofrequency catheter ablation for tachydysrhythmias. Anesthesiology 1995 82 : 884 887.
2. Erb TO, Kanter RJ, Hall JM, Gan TJ, Kern FH, Schulman SR. Comparison of electrophysiologic effects of propofol and isoflurane-based anesthetics in children undergoing radiofrequency catheter ablation for supraventricular tachycardia. Anesthesiology 2002 96 : 1386 1394.
3. Vernooy K, Delhaas T, Cremer OL, Di Diego JM, Oliva A, Timmermans C, Volders PG, et al. Electrocardiographic changes predicting sudden death in propofol-related infusion syndrome. Heart Rhythm 2006 3 : 131 137.
4. Parke TJ, Stevens JE, Rice AS, Greenaway CL, Bray RJ, Smith PJ, Waldmann CS, et al. Metabolic acidosis and fatal myocardial failure after propofol infusion in children: Five case reports. BMJ 1992 305 : 613 616.
5. Bray RJ. Propofol infusion syndrome in children. Paediatr Anaesth 1998 8 : 491 499.
6. Cornfield DN, Tegtmeyer K, Nelson MD, Milla CE, Sweeney M. Continuous propofol infusion in 142 critically ill children. Pediatrics 2002 110 : 1177 1181.
7. Sochala C, Deenen D, Ville A, Govaerts MJ. Heart block following propofol in a child. Paediatr Anaesth 1999 9 : 349 351.
8. Withington DE, Decell MK, Al Ayed T. A case of propofol toxicity: Further evidence for a causal mechanism. Paediatr Anaesth 2004 14 : 505 508.
9. Wysowski DK, Pollock ML. Reports of death with use of propofol (Diprivan) for nonprocedural (long-term) sedation and literature review. Anesthesiology 2006 105 : 1047 1051.
10. Cullen PM, Turtle M, Prys-Roberts C, Way WL, Dye J. Effect of propofol anesthesia on baroreflex activity in humans. Anesth Analg 1987 66 : 1115 1120.
11. Ebert TJ, Muzi M. Propofol and autonomic reflex function in humans. Anesth Analg 1994 78 : 369 375.
12. Brussel T, Theissen JL, Vigfusson G, Lunkenheimer PP, Van Aken H, Lawin P. Hemodynamic and cardiodynamic effects of propofol and etomidate: Negative inotropic properties of propofol. Anesth Analg 1989 69 : 35 40.
13. Wu MH, Su MJ, Sun SS. Age-related propofol effects on electrophysiological properties of isolated hearts. Anesth Analg 1997 84 : 964 971.
14. Grant AO. Electrophysiological basis and genetics of Brugada syndrome. J Cardiovasc Electrophysiol 2005 16 (Suppl 1 S3 S7.
15. Felmet K, Nguyen T, Clark RS, Orr D, Carcillo J. The FDA warning against prolonged sedation with propofol in children remains warranted. Pediatrics 2003 112 : 1002 1003.