Comparison between a liquid chromatography-tandem mass spectrometry assay and a fluorescent polarization immunoassay to measure whole blood everolimus concentration in heart and renal transplantations

Journal of Clinical Laboratory Analysis

Volumn 22, Issue 4, 2008, Pages 282-285

  Dailly, Eric ^a,b   Deslandes, G ^a   Hourmant, M ^a   Petit, T ^c   Renaud, C ^a   Treilhaud, M ^c   Jolliet, P ^a,b  

^a HÔTEL DIEU   (France)

^b Universite de Nantes   (France)

^c CHU de Nantes   (France)

Author keywords

Chromatography; Everolimus; Immunoassay; Therapeutic drug monitoring

Indexed keywords

EVEROLIMUS;

ADULT; ARTICLE; BLOOD; CLINICAL ARTICLE; COMPARATIVE STUDY; CORRELATION ANALYSIS; DRUG MONITORING; FEMALE; FLUORESCENCE POLARIZATION IMMUNOASSAY; HEART TRANSPLANTATION; HUMAN; KIDNEY TRANSPLANTATION; LINEAR REGRESSION ANALYSIS; LIQUID CHROMATOGRAPHY; MALE; RECIPIENT; STATISTICAL SIGNIFICANCE; STUDENT T TEST; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COHORT STUDIES; DRUG MONITORING; FEMALE; FLUORESCENCE POLARIZATION IMMUNOASSAY; HEART TRANSPLANTATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; SIROLIMUS; TANDEM MASS SPECTROMETRY;

EID: 48249148735     PISSN: 08878013     EISSN: 10982825     Source Type: Journal    
DOI: 10.1002/jcla.20258     Document Type: Article

References (9)

1. Dunn C, Croom KF. Everolimus: A review of its use in renal and cardiac transplantation. Drugs 2006;66:547-570.
2. Oellerich M, Armstrong VW. The role of therapeutic drug monitoring in individualizing immunosuppressive drug therapy: Recent developments. Ther Drug Monit 2006;28:720-725.
3. Khoschsorur G, Fruehwirth F, Zelzer S, Stettin M, Halwachs-Baumann G. Comparison of fluorescent polarization immunoassay (FPIA) versus HPLC to measure everolimus blood concentrations in clinical transplantation. Clin Chim Acta 2007;380:217-221.
4. Baldelli S, Crippa A, Gabrieli R, et al. Comparison of the Innofluor certican assay with HPLC-UV for the determination of everolimus concentrations in heart transplantation. Clin Biochem 2006;39:1152-1159.
5. Salm P, Warnholtz C, Boyd J, Arabshahi L, Marbach P, Taylor PJ. Evaluation of a fluorescent polarization immunoassay for whole blood everolimus determination using samples from renal transplant recipients. Clin Biochem 2006;39:732-738.
6. Koal T, Deters M, Casetta B, Kaever V. Simultaneous determination of four immunosuppressants by means of high speed and robust on-line solid phase extraction-high performance liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2004;805:215-222.
7. Strom T, Haschke M, Boyd J, et al. Crossreactivity of isolated everolimus metabolites with the Innofluor Certican immunoassay for therapeutic drug monitoring of everolimus. Ther Drug Monit 2007;29:743-749.
8. Taylor PJ. Internal standard selection for immunosuppressant drugs measured by high-performance liquid chromatography tandem mass spectrometry. Ther Drug Monit 2007;29:131-132.
9. Hoogtanders K, van der Heijden J, Stolk LM, Neef C, Christiaans M, van Hooff J. Internal standard selection for the high-performance liquid chromatography tandem mass spectroscopy assay of everolimus in blood. Ther Drug Monit 2007;29:673-674.